Total Knee Replacement Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Cause (Osteoarthritis, Rheumatoid arthritis, Post-traumatic arthritis), By Material (Metal-plastic, Ceramic-ceramic, Ceramic-plastic, Metal-metal), By Implant Fixation (Cemented, Cement less, Hybrid), By End-User (Hospitals, Orthopedic Centers, Other), By Region and Competition, 2020-2030F

Market Overview

Global Total Knee Replacement Market was valued at USD 8.99 billion in 2024 and is expected to reach USD 11.25 billion by 2030 with a CAGR of 3.85% during the forecast period. The global market for Total Knee Replacement is experiencing significant growth, driven by the rising prevalence of osteoarthritis coupled with rise in the geriatric population, which is anticipated to bolster the growth of the market in the upcoming years. The rising awareness among the population about the new innovations and designs of knee implants and advanced technologies such as robot-assisted knee surgeries are surging the demand for knee replacement medical procedures across the world. This contributes to the growth of this market. For instance, in 2021, Zimmer Biomet Holdings, Inc. and Canary Medical declared that U.S. Food and Drug Administration (FDA) has granted De Novo classification and authorization to market the tibial extension for Persona IQ, the world's first and only smart knee cleared by the FDA for total knee replacement surgery.

Key Market Drivers

Rising Obesity and Osteoarthritis Epidemic

A key driver boosting the global TKR market is the escalating prevalence of obesity, a primary risk factor for osteoarthritis, particularly of the knee. Government-backed health data demonstrates the impact of weight on surgical demand. In Australia, researchers analyzed nearly 192,000 TKR cases and found that 35% of total knee replacements in 2018 were attributable to overweight or obesity, accounting for over 14,000 procedures nationally. This means that even modest weight loss could significantly reduce demand: Australian estimates suggest that moving just one BMI category lower could avoid approximately 20% of knee replacement surgeries, translating into thousands fewer procedures each year. As obesity rates rise globally—including in the U.S., Europe, and Asia—the corresponding surge in osteoarthritis is fueling expanded demand for knee replacement surgeries. Many nations’ health ministry’s now include weight management and preventive joint health in public initiatives, indirectly promoting TKR volume through population-level risk factor reduction programs.

Aging Populations and Growing Surgical Capacity

Increasing life expectancy and aging demographics worldwide are pushing more patients into the 60–80-year age bracket, where total knee replacements are most performed. For example, data from the UK’s National Joint Registry (NJR) revealed that in 2023, there were approximately 116,845 primary knee replacement procedures, with a mean patient age of 69.3 years—and 55% of those surgeries were in women. Similarly, English NHS statistics show that nearly 100,000 knee replacements were performed annually, particularly in elderly cohorts aged 75–79, with incidence rates exceeding 600 per 100,000 population. These official figures reflect governments’ support for elective orthopaedic expansion, including funding for hospitals, training of orthopedic specialists, and national registry tracking. In countries like the UK, Australia, and Canada, surgical capacity has expanded through both public and private channels—resulting in significant growth in total knee replacement throughput.

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Key Market Challenges

Surgical Backlogs and Long Wait Times

One major challenge facing the TKR market is persistent surgical backlog and wait time pressures in public healthcare systems. In England, there are now over 7.6 million patients waiting for elective procedures, with many waiting far beyond 18 weeks—especially for hip and knee replacements. As of late 2024, population-wide waiting lists in England stood at around 6.3 million people, many enduring delays of several months or longer. These backlogs have two consequences: First, patients often defer surgery until mobility and overall physical health deteriorate, increasing complexity and cost. Second, long NHS waits have driven many to seek private-sector options, affecting demand forecasts and public–private capacity dynamics. Governments are responding with policy reforms, increased funding, and public–private partnerships to tackle the elective surgery backlog—but resource constraints remain a critical bottleneck for scaling TKR delivery efficiently.

Health Inequality and Access Disparities

Healthcare access disparities present another challenge for global knee replacement growth. Population-based studies from England and Australia show that TKR provision varies significantly by socioeconomic status, geography, and ethnicity. For instance, the UK National Joint Registry recorded overall knee replacement rates increasing from 33 to 46 per 10,000 person-years between 2007 and 2017—but those in the least affluent areas received fewer joint replacements relative to need, compared to those in more advantaged areas. Similarly in Australia’s public health data, individuals living in remote Indigenous communities or lower‑income regions often face lower access to elective knee surgeries, despite high osteoarthritis burden. These inequities challenge equitable TKR market growth, particularly where public systems under-invest in rural or disadvantaged populations. Government strategies now increasingly target outreach and subsidized surgery for underserved groups—but disparities persist.

Key Market Trends

Growth in Private Sector & Independent Hospital Procedures

One notable trend is the shift of TKR procedures into private hospitals and independent sector providers, supported by government funding mechanisms. UK NHS data indicates that while the total number of primary knee replacements has risen to 116,845 in 2023, public NHS hospitals have yet to reach 2019 volumes. Growth has primarily come from independent providers, as NHS capacity remains constrained. This public‑private outsourcing model is mirrored across other countries, where government health plans reimburse surgeries performed in accredited private facilities to reduce waiting times. This trend signifies evolving health policy priorities: governments leverage private infrastructure to meet increasing elective surgery demand—especially for high-volume, routine procedures like TKR. As private-sector share grows, the overall knee replacement market continues expanding beyond constraints of public system capacity.

Preventive Health Policies Targeting Obesity to Reduce TKR Demand

Governments worldwide are adopting preventive strategies focused on obesity reduction to curb future osteoarthritis and TKR demand. In Australia, projections from official health agencies indicate that without intervention, TKR incidence could rise by up to 276% by 2030, driven largely by escalating obesity rates. Conversely, government modeling shows that reducing overweight and obesity populations by even 1‑5% could prevent up to 8,062 knee replacement surgeries, saving AUSD 170 million in healthcare expenses. These public health policies—incorporating exercise promotion, diet education, and early intervention clinics—seek to mitigate future surgical demand. Such preventive initiatives not only help reduce TKR volume but also influence the surgical market by delaying the need for replacements. As national health ministry’s increasingly emphasize obesity control, TKR projections may shift from purely increase to moderated growth—reflecting policy efficacy.

Segmental Insights

Cause Insights

Based on Cause, Osteoarthritis holds the largest market share in the Global Total Knee Replacement Market. Osteoarthritis is the leading cause of total knee replacement procedures globally, and it holds the largest market share among all causative categories such as rheumatoid arthritis and post-traumatic arthritis. Osteoarthritis is a degenerative joint disease that results from the breakdown of cartilage and underlying bone in the knee, causing pain, stiffness, and reduced mobility. As this condition primarily affects older adults, its prevalence increases with the aging global population. According to the World Health Organization (WHO), approximately 528 million people worldwide were living with osteoarthritis in 2019, with the knee being one of the most affected joints. The Centers for Disease Control and Prevention (CDC) further notes that knee osteoarthritis accounts for nearly 80% of the total osteoarthritis burden in the U.S. These statistics underline the scale and impact of this condition on public health and healthcare systems, reinforcing why it dominates the total knee replacement market.

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Regional Insights

Based on the region, North America holds the largest market share in the Global Total Knee Replacement Market. North America continues to dominate the global total knee replacement market due to a combination of advanced healthcare infrastructure, high healthcare expenditure, and a well-established reimbursement system. The region benefits from early adoption of innovative medical technologies and surgical techniques, which contributes to improved patient outcomes and a higher volume of knee replacement procedures. Additionally, the availability of skilled orthopedic surgeons and widespread access to state-of-the-art hospitals and outpatient surgery centers reinforces North America’s leadership position. A key factor contributing to North America’s market share is the rising incidence of osteoarthritis, which is a leading cause of disability among the elderly. According to the Centers for Disease Control and Prevention (CDC), nearly 32.5 million adults in the United States suffer from osteoarthritis, significantly driving demand for knee replacement surgeries. Furthermore, the aging population in the region is growing rapidly. The U.S. Census Bureau projects that by 2034, older adults will outnumber children for the first time in U.S. history, further increasing the need for joint replacement procedures.

Recent Developments

• In June 2024, DePuy Synthes received 510(k) FDA clearance for the clinical application of the VELYS Robotic-Assisted Solution in Unicompartmental Knee Arthroplasty (UKA). This approval is expected to increase the company’s reputation and its competitiveness in the market.
• In June 2024, Zimmer Biomet entered into a distribution agreement with THINK Surgical, Inc. to offer TMINI Miniature Robotic System for total knee arthroplasty.
• In June 2024, DePuy Synthes, a group of Johnson & Johnson, obtained 510(k) clearance from the U.S. FDA for the VELYS Robotic-Assisted Solution in Unicompartmental Knee Arthroplasty (UKA).
• In March 2023, Stryker announced the launch of Mako Total Knee 2.0, the next chapter in Mako SmartRobotics. Mako Total Knee 2.0 was designed to deliver trusted outcomes and provide great user experience. This launch increased the company’s product range and enabled them with increased customer base.

Key Market Players

• SurgTech Inc.
• Zimmer Biomet Holdings, Inc.
• Think Surgical Inc.
• Corin Group
• Smith & Nephew plc
• Stryker Corporation
• Aesculap, Inc.
• Medacta International SA
• Johnson & Johnson Services, Inc.
• Exactech, Inc.

Report Scope:

In this report, the Global Total Knee Replacement Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Total Knee Replacement Market, By Cause:

o   Osteoarthritis

o   Rheumatoid arthritis

o   Post-traumatic arthritis

• Total Knee Replacement Market, By Material:

o   Metal-plastic

o   Ceramic-ceramic

o   Ceramic-plastic

o   Metal-metal

• Total Knee Replacement Market, By Implant Fixation:

o   Cemented

o   Cement less

o   Hybrid

• Total Knee Replacement Market, By End User:

o   Hospitals

o   Orthopedic Centers

o   Other

• Total Knee Replacement Market, By Region:

o   North America

§  United States

§  Mexico

§  Canada

o   Europe

§  France

§  Germany

§  United Kingdom

§  Italy

§  Spain

o   Asia-Pacific

§  China

§  India

§  South Korea

§  Japan

§  Australia

o   South America

§  Brazil

§  Argentina

§  Colombia

o   Middle East and Africa

§  South Africa

§  Saudi Arabia

§  UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies presents in the Global Total Knee Replacement Market.

Available Customizations:

Global Total Knee Replacement Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

• Detailed analysis and profiling of additional market players (up to five).

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