The Global Tangential Flow Filtration Market is anticipated to
witness impressive growth during the forecast period. This can be ascribed to rising advantages of
tangential flow filtration over the normal flow filtration along with
increasing adoption of single use technologies and growing research and
development in pharma and biotech companies. Also, growing usage of the TFF
technology in different downstream processes is expected to drive the growth of
the market during the forecast period. Additionally, the advantages of tangential flow filtration
(TFF) for using as a high performance and reproducible operations in the
biotechnology research and increasing investments for the development of novel
TFF products by major companies are driving the growth of the market during the forecast
period. In September 2021, ABEC, a
dominant player that delivers single-use integrated solutions & services
for biopharmaceutical manufacturing, announced the launch of their new TFF
system called Custom Single Run (CSR) Tangential Flow Filtration (TFF) system,
in order to appreciably expand downstream productivity for their bioprocess
customers. Brady Cole, the VP of Equipment Solutions at ABEC, mentioned in a
statement that traditional single-use TFF systems are cramped to a much lower
flow rate so as to avoid bursting. But their CSR TFF having flow rates of more
than 240 liters per minute, makes process times shorter to attain high product
concentrations.
Increasing
demand for biopharmaceuticals and biologics
Biopharmaceuticals
and biologics have a significant impact on the growth of the global tangential
flow filtration (TFF) market. Biopharmaceuticals and biologics require highly efficient and
reliable purification processes to ensure that they are safe and effective for
patients. TFF is one of the most commonly used methods for the purification of
biopharmaceuticals and biologics, which is driving the demand for TFF systems. The complexity of
biopharmaceuticals and biologics has driven innovation in TFF technology,
leading to the development of new and improved TFF systems. These systems are
designed to improve the efficiency, scalability, and reliability of the TFF
process, which is essential for the production of biopharmaceuticals and
biologics. The
biopharmaceutical industry is growing rapidly, driven by the increasing
prevalence of chronic diseases and the aging population. This growth is driving
the demand for TFF systems as biopharmaceutical manufacturers require efficient
and cost-effective purification processes. The development of new
biopharmaceuticals and biologics requires extensive research and development,
which drives the demand for TFF systems. TFF is essential for the purification of
small molecules, making it an essential technology for biopharmaceutical
research and development.
The
development and approval of several COVID-19 vaccines has been a major focus in
the biologics industry in the past few years. Multiple vaccines have been
developed using different platforms, including mRNA and viral vector
technologies, and have been authorized for emergency use in many countries. There have been several new
gene therapies approved in the past few years, including Zolgensma, a gene
therapy for spinal muscular atrophy, and Luxturna, a gene therapy for inherited
retinal dystrophy. Gene therapies use modified viruses to deliver a functional
copy of a defective gene to patients with genetic diseases. CAR-T cell therapies are a
type of immunotherapy that involves modifying a patient's own T-cells to target
and destroy cancer cells. Several CAR-T cell therapies have been approved in
recent years, including Kymriah and Yescarta, which are used to treat certain
types of leukemia and lymphoma.
Driving
innovation in TFF technology
The
complexity of biopharmaceuticals and biologics has driven innovation in TFF
technology, leading to the development of new and improved TFF systems. These
systems are designed to improve the efficiency, scalability, and reliability of
the TFF process, which is essential for the production of biopharmaceuticals
and biologics. Innovation
in TFF technology is the development of new materials and membranes that can
improve the efficiency and performance of TFF systems. For example, the use of
high-performance polymeric membranes with improved fouling resistance and
selectivity can lead to higher throughput and more efficient separation of
target molecules. These innovations can make TFF technology more attractive to
biopharmaceutical companies and other industries that require high-purity
separations. Innovation
in TFF technology is the development of new TFF systems that are more
automated, efficient, and cost-effective. For example, the use of microfluidic
devices, automated control systems, and integrated sensors can improve the
precision and reproducibility of TFF separations, while also reducing the time
and cost required to perform these separations. These innovations can make TFF
technology more accessible to a wider range of users, from small biotech
startups to large pharmaceutical companies.
Research
and development of new biopharmaceuticals and biologics
Research
activities play a significant role in the growth of the global tangential flow
filtration (TFF) market.
Research
activities are essential for identifying new applications for TFF. As
researchers better understand the capabilities and limitations of TFF, they can
develop new and innovative applications for the technology, leading to new
market opportunities.
Research
activities can help optimize TFF processes by identifying the best membrane
materials, geometries, and operating conditions for specific applications. This
leads to more efficient and effective TFF processes, reducing costs and
improving performance.
Research
activities drive innovation in TFF technology, leading to the development of
new and improved TFF systems. These systems are designed to be more efficient,
scalable, and reliable, leading to increased adoption and use of TFF in the
biopharmaceutical industry.
Research
activities can help researchers better understand the mechanisms behind TFF,
leading to improved process control and optimization. This leads to more
efficient and effective TFF processes, reducing costs and improving
performance. Research
activities often involve collaboration and knowledge sharing between academic
institutions, industry, and government. This collaboration can lead to the
development of new TFF applications and technologies, as well as improved
understanding of TFF mechanisms.
Government
support for the growth of life science industry
Government
support can play a significant role in the growth of the global tangential flow
filtration (TFF) market.
Governments
can provide funding for research and development of TFF technology. This can
lead to the development of new and improved TFF systems and applications,
driving innovation and growth in the market. Governments can establish regulations
and guidelines for TFF systems and applications, ensuring the safety and
efficacy of TFF processes. Clear and consistent regulations can also reduce
barriers to entry for new players in the market. Governments can provide support for the
commercialization of TFF technology, such as tax incentives or grants for
companies that invest in TFF research and development. This can incentivize
companies to invest in TFF technology, leading to increased adoption and use of
the technology in the biopharmaceutical industry. Governments can invest in infrastructure
to support the growth of the TFF market, such as funding for the construction
of TFF manufacturing facilities or upgrades to existing facilities. This can
increase the capacity for TFF production, reducing costs and increasing
efficiency. Governments
can negotiate international trade agreements that reduce barriers to the export
and import of TFF technology and products. This can increase the market reach
of TFF companies, leading to increased adoption and use of the technology
globally.
Download Free Sample Report
Recent Developments
·
In
February 2022, Pall Corporation launched its new range of Cadence single-pass
TFF systems, which are designed for the continuous processing of
biopharmaceuticals and other high-value products.
·
In
January 2022, Sartorius AG announced a collaboration with the French biotech
company, TreeFrog Therapeutics, to develop scalable cell culture systems for
the production of induced pluripotent stem cells (iPSCs).
·
Allegro
STR 1000 Single-Use Stirred Tank Bioreactor System (2019) – Pall Corporation
launched the Allegro STR 1000 Single-Use Stirred Tank Bioreactor System, which
incorporates TFF technology for continuous cell retention and clarification
during bioprocessing.
·
Mustang
XT Acrodisc Unit (2019) - Merck KGaA launched the Mustang XT Acrodisc Unit, a
single-use TFF device that enables efficient clarification and concentration of
biopharmaceuticals.
·
SoloHill
Engineering SoloStep Disposable TFF Capsules (2019) - SoloHill Engineering
launched the SoloStep Disposable TFF Capsules, a line of single-use TFF
capsules that are designed to be easy to use and cost-effective for small-scale
bioprocessing applications.
·
XCell
ATF 2.5 Automation System (2020) - Repligen Corporation launched the XCell ATF
2.5 Automation System, an automated TFF system that utilizes alternating
tangential flow (ATF) technology to enable continuous cell culture perfusion.
Market
Segmentation
Global Tangential
Flow Filtration market can be segmented by product, membrane material,
technique, application, end user, by region and competitive landscape. Based on
the product, the market can be segmented into
Single Use Systems, Reusable Systems, Membrane Filters, Filtration Accessories.
Based on membrane material, the market can be segmented into PES, Polyvinylidene Difluoride, Nylon, PTFE,
Mixed cellulose ester & cellulose acetate, PCTE, Regenerated Cellulose, and
Other membrane materials. Based on the technique, the market can be
differentiated into Microfiltration, Ultrafiltration, Nanofiltration, and Other
Techniques. Based on application, the market can be segmented into Final
product processing, Raw material filtration, Cell separation, Water
purification, Air purification. Based on end user, the market can be
differentiated into Pharmaceutical & Biotechnology companies, Contract
research organization, Academic & Research institutes. Regionally, North America dominates the market
among Asia Pacific, Europe, Middle East & Africa, and South America. Among
the different countries, the United States dominates the Global Tangential Flow
Filtration Market on account of the growing well-developed laboratories in the country.
Market Players
Merck KGAA., Danaher Corporation, Sartorius AG, Parker Hannifin Corporation,
Repligen Corporation, Alfa
Laval Corporate AB., Andritz, Meissner Filtration Products Inc., Cole Parmer Instrument Company Inc., Sterlitech
Corporation are
some of the leading players operating in the Global Tangential Flow Filtration Market.
|
Attribute
|
Details
|
|
Base
Year
|
2022
|
|
Historic
Data
|
2018 – 2021
|
|
Estimated
Year
|
2023
|
|
Forecast
Period
|
2024 – 2028
|
|
Quantitative
Units
|
Revenue in USD Million, and CAGR for 2018-2022 and 2023-2028
|
|
Report
Coverage
|
Revenue
forecast, company share, competitive landscape, growth factors, and trends
|
|
Segments Covered
|
By Product
By Membrane Material
By Technique
By Application
By End User
By Region
|
|
Regional
scope
|
North
America; Europe; Asia Pacific; South America; Middle East & Africa
|
|
Country
scope
|
United States; Canada; Mexico; France; Germany; United
Kingdom; Italy; Spain; China; India; Japan; South Korea; Australia; Brazil; Argentina;
Colombia; South Africa; Saudi Arabia; UAE
|
|
Key
companies profiled
|
Merck
KGAA., Danaher Corporation., Sartorius AG., Parker Hannifin Corporation.,
Repligen Corporation., Alfa Laval Corporate AB., Andritz., Meissner
Filtration Products Inc., Cole Parmer Instrument Company Inc., Sterlitech
Corporation.
|
|
Customization
scope
|
10% free report customization with purchase. Addition or
alteration to country, regional & segment scope.
|
|
Pricing
and purchase options
|
Avail
customized purchase options to meet your exact research needs. Explore purchase options
|
|
Delivery
Format
|
PDF and Excel through
Email (We can also provide the editable version of the report in PPT/Word
format on special request)
|
Report Scope:
In this report, Global Tangential
Flow Filtration Market has been segmented into the following categories, in
addition to the industry trends which have also been detailed below:
- Tangential Flow Filtration Market,
By Product:
o
Single use systems
o
Reusable Systems
o
Membrane Filters
o
Filtration Accessories
- Tangential Flow Filtration Market,
By Membrane Material:
o
PES
o
Polyvinylidene Difluoride
o
Nylon
o
PTFE
o
Mixed Cellulose Ester & Cellulose Acetate
o
PCTE
o
Regenerated Cellulose
o
Other Membrane Materials
- Tangential Flow Filtration Market,
By Technique:
o Microfiltration
o Ultrafiltration
o Nanofiltration
o Other
Techniques
- Tangential Flow Filtration Market, By Application:
o Final Product Processing
o Raw Material Filtration
o Cell Separation
o Water Purification
o Air Purification
- Tangential Flow Filtration Market, By End User:
o Pharmaceutical & Biotechnology Companies
o Contract Research Organization
o Academic & Research Institutes
- Tangential Flow Filtration Market,
By Region:
o
North
America
§
United States
§
Canada
§
Mexico
o Europe
§ France
§ Germany
§ United Kingdom
§ Italy
§ Spain
o
Asia
Pacific
§
China
§
India
§
Japan
§
South
Korea
§
Australia
o
South
America
§
Brazil
§
Argentina
§
Colombia
o
Middle
East & Africa
§
South
Africa
§
Saudi
Arabia
§
UAE
Competitive Landscape
Company
Profiles: Detailed
analysis of the major companies present in the Global Tangential Flow
Filtration Market.
Available Customizations:
With the given market data, TechSci
Research offers customizations according to a company’s specific needs. The following
customization options are available for the report:
Company Information
- Detailed analysis and profiling of additional market
players (up to five).
Global Tangential Flow
Filtration Market is an upcoming report to be released soon. If you wish an early
delivery of this report or want to confirm the date of release, please contact
us at [email protected]