Single Use Consumables Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product (Tubings, Connectors, Disconnector, Adapters, Valves, Disposable Capsule Filter, Single Use Sensors), By Application (Filtration, Cell culture & Mixing, Storage, Sampling, Other Application), By End User ( Biopharmaceutical & Pharmaceutical Companies, OEMS (Original Equipment Manufacturers), Contract Research Organizations & Contract Manufacturing Organizations, Academic & Research Institutes), By Region and Competition, 2021-2031F

Forecast Period	2027-2031
Market Size (2025)	USD 3.20 Billion
CAGR (2026-2031)	5.92%
Fastest Growing Segment	Biopharmaceutical & Pharmaceutical Companies
Largest Market	North America
Market Size (2031)	USD 4.52 Billion

Market Overview

The Global Single Use Consumables Market will grow from USD 3.20 Billion in 2025 to USD 4.52 Billion by 2031 at a 5.92% CAGR. The Global Single Use Consumables Market comprises disposable components such as bioreactor bags, filtration assemblies, tubing, and connectors employed primarily in biopharmaceutical manufacturing to replace traditional stainless-steel equipment. The market is propelled by fundamental drivers including the elimination of complex cleaning and sterilization validation requirements, which substantially lowers initial capital expenditures and reduces the risk of cross-contamination. Furthermore, these consumables offer critical manufacturing flexibility, allowing facilities to rapidly switch between product lines and accelerate commercialization timelines.

Despite these operational advantages, the sector faces a significant challenge regarding environmental sustainability and the management of solid plastic waste generated by disposable workflows. Stakeholders are increasingly pressured to balance the efficiency of single-use systems with corporate carbon footprint goals and waste disposal regulations. According to the Bio-Process Systems Alliance, in 2025, biopharmaceutical manufacturing-related plastic waste was estimated to represent less than 0.002% of global plastic waste, a statistic that underscores the nuance required when addressing industry disposal strategies.

Key Market Drivers

The reduction of upfront capital expenditure and operational costs is a primary force accelerating the adoption of single-use consumables. Biopharmaceutical manufacturers are increasingly prioritizing these disposable components over traditional stainless-steel infrastructure to eliminate the financial burden of complex cleaning and sterilization validation. By shifting from heavy initial investments in fixed equipment to an operational expense model based on consumables, facilities can significantly optimize their financial agility and resource allocation. This trend is evident in the divergence between equipment and consumable sales; while capital equipment investment has faced headwinds, the demand for disposable solutions remains robust. According to Sartorius Stedim Biotech, July 2025, in the 'Half-year results 2025' press release, the company’s sales revenue increased by 9.4% in constant currencies during the first half of the year, a growth trajectory explicitly driven by the high-margin recurring business with single-use consumables.

Simultaneously, the rapid expansion of the Contract Development and Manufacturing (CDMO) sector serves as a critical volume driver for the market. As CDMOs manage diverse client portfolios requiring distinct manufacturing processes, they rely heavily on single-use technologies to ensure rapid changeovers and mitigate cross-contamination risks without time-consuming sanitation cycles. This operational flexibility allows contract manufacturers to scale capacity quickly in response to surging global demand for biologics. According to Lonza, July 2025, in the 'Half-Year Report 2025', its CDMO business division delivered sales of CHF 3.1 billion for the first six months of the year, representing a 23.1% growth at constant exchange rates. This sector-wide expansion is further corroborated by broader industry sentiment regarding capacity scaling. According to Cytiva, in 2025, 56% of biopharma executives agreed that domestic manufacturing of biologics is set to increase dramatically over the next three years, underscoring the sustained requirement for disposable manufacturing components.

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Key Market Challenges

The environmental sustainability challenge regarding the management of solid plastic waste acts as a significant restraint on the expansion of the Global Single Use Consumables Market. As major biopharmaceutical companies aggressively pursue corporate net-zero targets and carbon neutrality, the reliance on disposable plastic components creates a direct conflict with these strategic environmental goals. This tension forces manufacturers to reconsider or delay the transition from stainless steel to single-use systems, as the latter inevitably results in substantial volumes of bio-contaminated waste that is difficult to recycle. Consequently, the misalignment between disposable workflows and strict corporate environmental governance slows market penetration and complicates procurement decisions.

The increasing volume of waste generated by these systems further intensifies this restraint by elevating disposal costs and compliance burdens. According to the International Society for Pharmaceutical Engineering, in 2024, it was reported that biopharmaceutical manufacturing-related plastic waste is projected to surge to 11,700 metric tons per year by 2028. This anticipated increase in waste tonnage presents a tangible liability for manufacturers, causing hesitation in the adoption of single-use consumables as stakeholders struggle to justify the long-term environmental footprint against operational gains.

Key Market Trends

The market is increasingly defined by the development of tailored solutions for cell and gene therapy (CGT) production, which demands specialized, closed-system consumables to maintain sterility. Unlike traditional biologics, CGT workflows require modular single-use assemblies capable of supporting patient-specific batches while mitigating cross-contamination. This shift necessitates the redesign of bioreactors and tubing kits to accommodate the unique volume and sensitivity requirements of viral vector and autologous cell manufacturing. The urgency for such dedicated infrastructure is reflected in recent regulatory milestones; according to the Alliance for Regenerative Medicine, January 2025, in the '2025 Cell & Gene State of the Industry Briefing', the sector achieved a record nine regulatory approvals for new cell and gene therapies in 2024, a surge that directly amplifies the demand for modality-specific disposable technologies.

Simultaneously, the integration of smart sensors and digital monitoring tools within single-use assemblies is fundamentally transforming process analytical technology (PAT). Manufacturers are actively embedding pre-calibrated, disposable sensors for critical parameters such as pH and dissolved oxygen directly into consumable bags and tubing, enabling real-time data acquisition without compromising system sterility. This digitalization facilitates tighter process control and supports the industry's transition toward automated, data-driven bioprocessing workflows. The commercial traction of these advanced monitoring solutions is robust; according to Repligen Corporation, February 2025, in the 'Fourth Quarter and Full Year 2024 Financial Results', the company reported that total orders outpaced sales by 6% during the quarter, a performance explicitly driven by the accelerated demand for its Analytics and Filtration franchises.

Segmental Insights

Biopharmaceutical and Pharmaceutical Companies represent the fastest-growing segment in the Global Single Use Consumables Market. This rapid expansion is primarily driven by the imperative to minimize cross-contamination risks and streamline manufacturing workflows. Unlike traditional stainless steel systems, single-use assemblies eliminate the need for extensive cleaning and sterilization validation, significantly reducing downtime. Regulatory bodies, such as the U.S. FDA, acknowledge the efficacy of these technologies in maintaining high sterility assurance and ensuring patient safety. Consequently, manufacturers are increasingly adopting these disposable solutions to improve operational flexibility and accelerate the commercialization of biologics and vaccines.

Regional Insights

North America maintains a dominant position in the Global Single Use Consumables Market, primarily driven by its robust biopharmaceutical infrastructure and substantial investments in research and development. The region benefits from the widespread adoption of single-use technologies by major pharmaceutical companies and contract manufacturing organizations seeking to enhance operational flexibility and minimize cross-contamination risks. Furthermore, stringent regulatory frameworks established by the U.S. Food and Drug Administration (FDA) actively encourage the implementation of disposable systems to ensure product sterility and manufacturing efficiency. This favorable environment, combined with the presence of key industry players, solidifies North America’s leadership in the global landscape.

Recent Developments

• In November 2025, Thermo Fisher Scientific inaugurated a new Bioprocess Design Center in Hyderabad, India, focused on advancing single-use bioprocessing capabilities. Established in collaboration with the local government, the facility was designed to support pharmaceutical companies in scaling up manufacturing for biologics and vaccines. The center featured state-of-the-art single-use bioreactors with capacities up to 500 liters, along with upstream and downstream processing systems. This development aimed to meet the growing demand for flexible and efficient bioproduction technologies in the region. The President of Asia Pacific for Thermo Fisher Scientific highlighted that the investment would foster innovation and skill development in the local life sciences ecosystem.
• In March 2025, ABEC introduced the Advanced Therapy Bioreactor, a breakthrough single-use platform specifically engineered for cell therapy manufacturing. This new system was designed to mimic the human circulatory system using proprietary hollow fiber membrane networks to ensure optimal nutrient delivery and waste removal. The platform provided a closed, automated environment that supported seamless scalability from benchtop to commercial production. By eliminating the need for mechanical agitation, the technology aimed to improve cell growth conditions for sensitive cell lines. The Chief Executive Officer of ABEC noted that this innovation would help overcome significant challenges in the production of advanced therapy medicinal products.
• In September 2024, Merck KGaA launched the first single-use reactor explicitly designed for the manufacturing of antibody-drug conjugates. The new device addressed the unique chemical compatibility and quality requirements of such complex therapeutics, which had previously limited the adoption of disposable technologies in this specific field. The reactor utilized a proprietary film technology to enhance durability and leak resistance while eliminating the cleaning steps associated with traditional stainless-steel vessels. The Head of Process Solutions at Merck KGaA explained that the innovation would enable biopharmaceutical companies to produce critical therapies more rapidly and safely by minimizing cross-contamination risks and improving turnaround times.
• In April 2024, Cytiva introduced a new single-use magnetic mixing system aimed at improving large-scale manufacturing for monoclonal antibodies and genomic medicines. Released at a major industry conference, the mixer was offered in capacities of up to 3000 liters and featured a hexagonal shape designed to enhance the mixing efficiency of floating powders. The system incorporated a novel biocontainer design intended to prevent leaks and ensure the integrity of high-value batches during processing. The President of Bioprocess at Cytiva emphasized that the technology was developed to solve flexibility and durability challenges faced by customers in buffer and cell culture media preparation.

Key Market Players

• DANAHER Corporation
• Repligen Corporation
• Thermo fisher scientific, Inc.
• Sartorius Stedim Biotech GmbH
• Compagnie de Saint-Gobain S.A
• Avantor, Inc.
• Sentinel Process Systems, Inc.
• Corning Incorporated
• Meissner Filtration Products, Inc.
• Parker-Hannifin Corporation

By Product	By Application	By End User	By Region
Tubings Connectors Disconnector Adapters Valves Disposable Capsule Filter Single Use Sensors	Filtration Cell culture & Mixing Storage Sampling Other Application	Biopharmaceutical & Pharmaceutical Companies OEMS (Original Equipment Manufacturers) Contract Research Organizations & Contract Manufacturing Organizations Academic & Research Institutes	North America Europe Asia Pacific South America Middle East & Africa

Report Scope:

In this report, the Global Single Use Consumables Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Single Use Consumables Market, By Product:

• Tubings
• Connectors
• Disconnector
• Adapters
• Valves
• Disposable Capsule Filter
• Single Use Sensors

• Single Use Consumables Market, By Application:

• Filtration
• Cell culture & Mixing
• Storage
• Sampling
• Other Application

• Single Use Consumables Market, By End User:

• Biopharmaceutical & Pharmaceutical Companies
• OEMS (Original Equipment Manufacturers)
• Contract Research Organizations & Contract Manufacturing Organizations
• Academic & Research Institutes

• Single Use Consumables Market, By Region:

• North America
• United States
• Canada
• Mexico
• Europe
• France
• United Kingdom
• Italy
• Germany
• Spain
• Asia Pacific
• China
• India
• Japan
• Australia
• South Korea
• South America
• Brazil
• Argentina
• Colombia
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE