Proteomics Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product (Reagents & Assays, Instruments, Software & Services), By Technology (Spectroscopy, Microarray instruments, Chromatography, X-ray crystallography, Protein Microarrays, Electrophoresis), By Application (Clinical Diagnostic, Drug Discovery, Diagnostic Biomarker Discovery, Others), By Type (Expression, Functional, Structural, Computational), By End User (Pharmaceutical and Biotechnology Companies, Research Institutes, CROs), By Region and Competition, 2020-2030F

Market Overview

Global Proteomics Market was valued at USD 24.11 Billion in 2024 and is expected to reach USD 45.87 Billion by 2030 with a CAGR of 11.32% during the forecast period. Proteomics, the study of proteomes on a large scale, is a crucial field. Proteomics is a powerful technique utilized for the identification of disease-associated proteins and the investigation of their production, function, and structure. It plays a crucial role in the discovery of prognostic markers and the diagnosis of various diseases, including cancer, infectious illnesses, malaria, and tuberculosis. Moreover, in the pharmaceutical sector, proteomics is extensively employed to elucidate the mechanisms of drug action and toxicity. Additionally, it is commonly applied in the identification and validation of biomarkers. The proteome is partially influenced by the underlying transcriptome, which encompasses all messenger RNA molecules in an organism. However, protein activity is influenced by various factors beyond gene expression levels. Proteomics has a wide range of applications. The rising prevalence of chronic and infectious diseases drives proteomics industry growth. WHO predicts that there will be over 35 million new cancer cases by 2050, a 77% surge from the approximately 20 million cases estimated in 2022. Moreover, the prevalence of disease increases the demand for pathogenesis research and advanced diagnostics and therapeutics. For instance, according to research published in Nature Communications in July 2024, scientists used a proteomics-based approach to identify effectors secreted by Rickettsia spp, thereby understanding the host-pathogen interface. 

In addition to elucidating protein-protein interactions and their involvement in metabolic pathways, proteomics enables the investigation of protein expression patterns, production and degradation rates, and steady-state abundance. It also allows the study of post-translational modifications, such as phosphorylation, which can alter protein function. Moreover, proteomics provides insights into the types of proteins present in specific cellular compartments, such as the mitochondrion, and the proteins involved in biological processes like the circadian rhythm, which regulates the sleep-wake cycle and repeats approximately every 24 hours.

Key Market Drivers

Increase In the Number of Patients Suffering from Cancer

The increasing incidence of cancer and other disorders is another crucial factor contributing to the growth of the global proteomics market. With the rising number of cancer cases worldwide, there is a pressing need for effective treatment options. This has resulted in extensive research and development in the field of life sciences, leading to significant advancements and discoveries.

One major breakthrough in this field is the characterization of human proteins, which has revolutionized the field of biomedicine. By studying gene expression at the proteome level, researchers can gain deeper insights into the intricate mechanisms underlying diseases like cancer. This constant research and development in the field of proteomics are anticipated to fuel the market's growth to a great extent. Through the application of proteomics techniques, researchers are able to extract highly significant biological information that greatly enhances our understanding of cancer biology. This knowledge can ultimately benefit patients by improving diagnosis, treatment, and overall patient care.

The continuous advancements in proteomics research not only help in identifying how proteins respond in dynamic environments, such as cancer patients, but also pave the way for the development of personalized medicine. By tailoring treatment plans based on an individual's unique proteomic profile, healthcare providers can maximize the effectiveness of therapies and minimize side effects. The increasing prevalence of cancer, along with the constant progress in proteomics research, holds immense potential for the global proteomics market. The ability to extract valuable insights from the proteome level opens up new opportunities for advancements in diagnosis, treatment, and personalized medicine, ultimately benefiting patients worldwide.

Increased Investments In R&D In Proteomics

The National Institutes of Health (NIH), a renowned institution in the United States, generously contributed a staggering amount of US$ 37 billion towards groundbreaking biomedical research. This substantial grant was specifically allocated to support life sciences research, aiming to deepen our understanding of the fundamental mechanisms underlying the occurrence of diseases. By investing in cutting-edge technologies and state-of-the-art facilities, the NIH is empowering scientists and researchers to explore novel approaches in disease prevention, diagnosis, and treatment. For instance, in January 2024, Standard BioTools merged with SomaLogic, thereby strengthening the innovation in multi-omics technology.

The NIH's commitment to advancing the frontiers of medical knowledge extends beyond the identification of crucial biomarkers and unraveling the complex interplay of genes and proteins. It encompasses a multidisciplinary approach that integrates genomics, proteomics, metabolomics, and other emerging fields to gain comprehensive insights into disease mechanisms. Through collaborative initiatives and partnerships with leading academic institutions and industry experts, the NIH fosters a vibrant ecosystem of discovery and innovation. This remarkable investment not only fuels breakthroughs in basic research but also supports the translation of scientific findings into tangible improvements in patient care. With its unwavering dedication to scientific excellence, the NIH is paving the way for advancements in the field of healthcare. By catalyzing transformative discoveries and nurturing the next generation of scientists, the NIH plays a pivotal role in shaping the future of medicine and improving human health and well-being on a global scale.

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Key Market Challenges

Expensive Instruments

The need for a longer period of time in laboratories increases the cost of treatment. This is primarily due to the expensive instruments and reagents used in the process, which limits the use of this technology in developing nations. One of the most commonly used methods in proteomics is X-ray crystallography. This method involves protein expression, gene cloning, protein crystallization, and purification. However, these procedures are time-consuming, resulting in higher costs. As a result, the adoption of these procedures in developing nations is limited. This presents a significant challenge to the growth of the market and will continue to hinder its progress in the long run.

To overcome this obstacle and promote market growth in developing nations, it is crucial to expand the accessibility and affordability of these technologies. By doing so, more laboratories and research institutions in these regions will be able to utilize these advanced techniques to study proteins and contribute to scientific advancements. This, in turn, can lead to improved healthcare solutions, better understanding of diseases, and the development of targeted therapies.

Furthermore, addressing the cost issue can also encourage collaborations between developed and developing nations in the field of proteomics. By sharing resources, knowledge, and expertise, it becomes possible to overcome the financial limitations and accelerate the progress of research and innovation. This collaborative approach can create a more inclusive and globally connected scientific community, where breakthroughs in proteomics are not limited by economic constraints.

The longer time required and higher costs associated with proteomic research in laboratories pose challenges to its widespread adoption in developing nations. However, by expanding the accessibility, affordability, and fostering international collaborations, we can overcome these obstacles and promote market growth in these regions. This will not only advance scientific knowledge but also contribute to improving healthcare outcomes for people around the world.

Experimental Challenges in Protein Structure Determination

One of the major challenges hindering the growth of the global proteomics market is the experimental difficulties associated with determining protein structures. Protein structure determination is a complex and intricate process that often requires the utilization of multiple techniques and expertise. Current methods, such as X-ray crystallography and NMR spectroscopy, although widely used, have their limitations and may not always yield successful results. The determination of protein structures becomes even more challenging when dealing with large, multi-domain proteins, membrane proteins, and proteins with flexible regions.

In addition to these challenges, the detection of post-translational modifications (PTMs) and the significant cost and time required for protein structure determination pose significant obstacles to the advancement of the field. The identification and characterization of PTMs play a crucial role in understanding protein function and regulation, but their detection can be technically demanding and time-consuming.

To overcome these challenges and foster the growth of the proteomics market, it is imperative to develop new techniques, improve existing methods, and encourage interdisciplinary collaboration. The inherent instability and flexibility of proteins present challenges that extend across various aspects of proteomics, impeding the market's progress in the forecast period. By addressing these experimental challenges and advancing our understanding of protein structures and functions, we can unlock new opportunities for innovation and drive the future development of the proteomics field.

Key Market Trends

Emergence Of Label-Free Quantification Techniques

The emergence of label-free quantification techniques is a major trend in the market. The global proteomics market has witnessed notable trends, including the rise of label-free quantification techniques. Label-free quantification, a revolutionary approach in proteomics, utilizes mass spectrometry-based methods to accurately measure proteins without the need for chemical or isotopic labels. By eliminating the use of labels, this technique offers enhanced accuracy, reproducibility, and cost-effectiveness, making it an attractive option for researchers. Moreover, label-free quantification enables the analysis of larger sample sizes, allowing for more comprehensive proteomic studies. Additionally, this approach avoids potential artifacts that may arise from labeling interference, ensuring the integrity of the protein quantification results. As the demand for high-throughput, reliable, and cost-effective proteomic analysis continues to grow, the adoption of label-free quantification techniques is expected to increase rapidly in the coming years, revolutionizing the field of proteomics and advancing our understanding of complex biological systems.

Integration of Artificial Intelligence

Artificial intelligence in proteomics is a well-known and rapidly growing trend in the field. The use of artificial intelligence in proteomics applications is already making significant advancements in the field of drug development. By considering how and why specific proteins interact, researchers can better understand the complexities of cell biology and determine the potential therapeutic or harmful effects of new medications.

In addition to the impact of artificial intelligence, there are several other market trends that are driving the expansion of the proteome market. The rise in drug discovery efforts, fueled by advancements in technology, is leading to the development of innovative proteomic technologies and techniques. Nano proteomics, in particular, is gaining increasing significance as it allows for the analysis of proteins at the nanoscale, providing valuable insights into their structure and function.

Furthermore, the advancement of proteomic technology is enabling new applications in various fields, including diagnostics, personalized medicine, and biomarker discovery. These advancements are expected to further accelerate the growth of the proteome market over the forecast period, opening up new opportunities for research and development in the field of proteomics.

Segmental Insights

Product Insights

Based on Product, the reagents & assays segment accounted for the highest share in the global revenue. This segment is expected to experience the fastest growth rate during the projected period. The significant growth can be attributed to the extensive use of reagents & consumables, kits, chemicals, and strips for the examination of various biological samples. These resources are widely utilized in academic institutions, research labs, and other establishments, thereby driving the demand for reagents & consumables and fueling the growth of this segment. Moreover, the market growth is further supported by the technological advancements in advanced instruments, such as 2-D electrophoresis protein analyzers. These innovative instruments enhance the speed, efficiency, and throughput of biological research, providing researchers with valuable tools to conduct their experiments and investigations. With such advancements, the market is expected to witness a positive growth trajectory in the coming years.

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Regional Insights

Based on Region, North America emerged as the dominant region, generating substantial revenue throughout the projected period. The growth of omics research, the need for reliable data reproducibility tools, and the focus on personalized treatments all contribute to this trend. Additionally, the market's expansion is facilitated by strategic alliances and collaborations among key regional enterprises. A notable example is the partnership between Symphogen and Thermo Fisher Scientific Inc., aimed at developing standardized platform methods for the efficient characterization and quality monitoring of complex therapeutic proteins.

Recent Developments

• In July 2024, Thermo Fisher Scientific Inc. acquired Olink Holding AB for USD 3.1 billion. This acquisition helped Thermo Fisher to expand its next-generation proteomics product portfolio.
• In May 2024, Bruker Corporation inaugurated its new production facility in Bremen, Germany. This inauguration is likely to enhance innovation, sustainability, and collaboration in mass spectrometry.  
• In August 2023, Danaher Corporation acquired a life science firm Abcam, thereby leveraging its product portfolio, including tools and reagents for proteomics.  
• Bruker Corporation launched the nanoElute 2 nano-LC in August 2022, along with MetaboScape and TASQ 2023 software to support fluxomics. They also introduced the latest advancements in PaSER intelligent acquisition, aiming to enhance research in protein-protein interactions (PPIs) and metaproteomics applications.
• In February 2021, Agilent Technologies Inc. unveiled the Agilent Dako SARS-CoV-2 IgG Enzyme-Linked Immunosorbent Assay (ELISA) kit. This kit is designed for the qualitative detection of immunoglobulin G (IgG) antibodies to SARS-CoV-2 in human serum or plasma.
• In December 2020, Thermo Fisher Scientific acquired Phitonex, Inc. This acquisition allows Thermo Fisher to expand its flow cytometry and imaging multiplexing capabilities, meeting the evolving needs of customers in protein and cell analysis research.

Key Market Players

• Illumina, Inc.
• Thermo Fisher Scientific Inc.
• Bruker Corporation
• Promega Corporation
• Agilent Technologies Inc.
• Merck KGaA
• Bio-Rad Laboratories, Inc.
• Danaher Corporation
• F Hoffmann-La Roche Ltd.
• Luminex Corporation

Report Scope:

In this report, the Global Proteomics Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Proteomics Market, By Product:

o   Reagents & Assays

o   Instruments

o   Software & Services

• Proteomics Market, By Technology:

o   Spectroscopy

o   Microarray instruments

o   Chromatography

o   X-ray crystallography

o   Protein Microarrays

o   Electrophoresis

• Proteomics Market, By Application:

o   Clinical Diagnostic

o   Drug Discovery

o   Diagnostic Biomarker Discovery

o   Others

• Proteomics Market, By Type:

o   Expression

o   Functional

o   Structural

o   Computational

• Proteomics Market, By End User:

o   Pharmaceutical and Biotechnology Companies

o   Research Institutes

o   CROs

• Proteomics Market, By Region:

o   North America

§  United States

§  Canada

§  Mexico

o   Europe

§  France

§  United Kingdom

§  Italy

§  Germany

§  Spain

o   Asia-Pacific

§  China

§  India

§  Japan

§  Australia

§  South Korea

o   South America

§  Brazil

§  Argentina

§  Colombia

o   Middle East & Africa

§  South Africa

§  Saudi Arabia

§  UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Proteomics Market.

Available Customizations:

Global Proteomics market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

• Detailed analysis and profiling of additional market players (up to five).