Automated Sample Preparation Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Application (Research and Development, Diagnostics), By Product Type (Kits and Consumables, Instruments), By End-User (Biotechnology and Pharmaceutical Companies, Clinical and Diagnostic Laboratories, Academic and Research Institutions), By Region and Competition, 2021-2031F

Forecast Period	2027-2031
Market Size (2025)	USD 2.42 Billion
CAGR (2026-2031)	10.10%
Fastest Growing Segment	Instruments
Largest Market	North America
Market Size (2031)	USD 4.31 Billion

Market Overview

The Global Automated Sample Preparation Market will grow from USD 2.42 Billion in 2025 to USD 4.31 Billion by 2031 at a 10.10% CAGR. Automated sample preparation refers to the utilization of robotic systems and software to manage the extraction, purification, and handling of biological or chemical samples prior to analysis. The primary drivers fueling this market include the critical necessity for improved reproducibility and the reduction of manual errors that can compromise data integrity. Additionally, the increasing demand for rapid processing in drug discovery and clinical diagnostics necessitates systems capable of handling large volumes of samples with speed and precision to meet modern laboratory standards.

The integration of advanced technologies remains a pivotal factor in market progression as laboratories seek greater efficiency. According to the Pistoia Alliance, in 2024, 68% of surveyed life science experts reported currently using Artificial Intelligence and Machine Learning in their laboratory work. This statistic highlights a supportive environment for the adoption of intelligent automated systems that streamline complex workflows. However, a significant challenge impeding broader expansion is the difficulty of integrating these platforms into existing legacy infrastructures. The high initial capital required for such comprehensive systems also poses a barrier for smaller laboratories and potentially stalls universal adoption despite the clear operational benefits.

Key Market Drivers

Expanding R&D investments by pharmaceutical and biotechnology firms act as a primary catalyst for the Global Automated Sample Preparation Market. As drug discovery becomes increasingly complex, major industry players are channeling historic levels of capital into research to accelerate the identification of viable therapeutic candidates. This surge in funding necessitates the adoption of high-throughput systems capable of processing vast libraries of compounds with speed and precision, thereby driving the uptake of automated solutions. For instance, according to Johnson & Johnson, January 2024, in its 'Fourth-Quarter and Full Year 2023 Results', the company reported a record full-year research and development investment of $15.1 billion to drive its pipeline innovation. Such massive financial commitments underscore the critical reliance on automated workflows to maximize the return on investment by shortening development timelines and ensuring data robustness in early-stage screening.

Simultaneously, the rising focus on operational efficiency and labor cost reduction is fundamentally reshaping laboratory management strategies. Laboratories are increasingly turning to automation to mitigate the impact of skilled personnel shortages and to eliminate the variability associated with manual handling. According to Siemens Healthineers, July 2024, in a survey of U.S. laboratory professionals, 89% of respondents agreed that their laboratories require automation to effectively keep up with increasing testing demands. By delegating repetitive tasks to robotic systems, facilities can significantly enhance throughput while minimizing human error. Highlighting this operational impact, according to Dispendix, November 2024, the integration of Next-Generation Sequencing (NGS) automation has been shown to reduce the need for manual sample processing by up to 80%, allowing scientists to redirect their focus toward high-value analysis and result interpretation.

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Key Market Challenges

The high initial capital required for comprehensive automated sample preparation systems acts as a significant restraint on the Global Automated Sample Preparation Market. While these platforms offer reproducibility and speed, the substantial upfront investment prevents a large segment of potential users, particularly small-to-medium-sized enterprises (SMEs) and academic research institutions, from transitioning away from manual processes. This cost barrier extends beyond the purchase of hardware to include expenses for software integration, specialized personnel training, and ongoing maintenance, creating a complex budgetary hurdle that delays procurement decisions and limits market penetration.

Financial constraints remain a measurable impediment to the adoption of advanced laboratory technologies. According to the Pistoia Alliance, in 2024, 20% of surveyed life science professionals cited financial barriers as a primary obstacle to the adoption of new technologies, an increase from the previous year. This rising concern regarding affordability highlights that despite the operational advantages, budgetary restrictions are directly stalling the universal implementation of intelligent automated systems. Consequently, the market experiences slower growth rates in cost-sensitive sectors, restricting the technology's expansion to well-funded pharmaceutical giants and reducing the overall addressable market volume.

Key Market Trends

The Shift Toward Sustainable and Green Sample Preparation Methods is reshaping product development as laboratories strive to minimize their environmental footprint. This trend prioritizes the reduction of plastic waste generated by consumables and the lowering of energy consumption in automated instrumentation to meet strict corporate governance mandates. Manufacturers are aggressively engineering eco-friendly systems to align with these evolving priorities. This industry-wide commitment is measurable; according to My Green Lab, November 2024, in the '2024 Carbon Impact of Biotech & Pharma Report', 31% of analyzed companies have now set medium-term Scope 1 and 2 targets aligned with a 1.5°C pathway. Consequently, vendors are redesigning workflows to minimize reagent usage and implementing circular economy principles to satisfy this rising demand for sustainable operations.

Simultaneously, the Expansion of Automation in Genomic and Proteomic Workflows is driven by the necessity to process complex, low-input samples with extreme sensitivity. Modern platforms are evolving beyond basic liquid handling to manage the rigorous demands of Next-Generation Sequencing (NGS), where precision in low-volume dispensing is paramount to preserve sample integrity. This technical leap allows researchers to automate difficult protocols that were previously limited to manual execution. Highlighting this advancement in sensitivity, according to Beckman Coulter Life Sciences, April 2024, in an announcement regarding its partnership with Watchmaker Genomics, their co-developed automated RNA library preparation method successfully supports input amounts as low as 1 ng. This underscores the market's trajectory toward sophisticated automation that enables high-fidelity results from minimal biological material.

Segmental Insights

The Instruments segment currently represents the fastest-growing category within the Global Automated Sample Preparation Market. This expansion is primarily driven by the increasing demand for high-throughput screening and the critical need to minimize manual errors in laboratory workflows. Laboratories are extensively adopting automated liquid handling systems to ensure consistency and reproducibility in research results. Furthermore, strict compliance requirements from regulatory bodies like the US Food and Drug Administration regarding data integrity and process validation compel pharmaceutical companies to integrate automated instrumentation, thereby fueling substantial segmental growth.

Regional Insights

North America maintains a leading position in the global automated sample preparation market due to the strong presence of established pharmaceutical and biotechnology firms. This dominance is driven by significant investments in research and development that require efficient laboratory workflows to manage high sample volumes. Additionally, stringent regulatory standards enforced by the U.S. Food and Drug Administration compel laboratories to adopt automation for improved data accuracy and compliance. The necessity to reduce manual errors and ensure reproducibility in clinical and diagnostic testing further reinforces market expansion across this region.

Recent Developments

• In April 2025, Revvity, Inc. obtained approval from the U.S. Food and Drug Administration for its Auto-Pure 2400 liquid handling platform used in conjunction with the T-SPOT.TB test. This regulatory milestone allowed the company to deploy an automated solution for latent tuberculosis detection, significantly increasing testing throughput for clinical laboratories. The system combined automated liquid handling with magnetic cell isolation technology to streamline the sample preparation process. By reducing manual intervention, the platform was designed to enhance laboratory productivity and maintain high standards of clinical performance and accuracy in infectious disease diagnostics.
• In September 2024, Opentrons Labworks Inc. released the Flex Prep robot, a new automated liquid handling system intended to simplify laboratory workflows for bench scientists. The product featured an intuitive, no-code touchscreen interface that allowed users to program and execute pipetting tasks without requiring extensive automation experience or programming skills. By bridging the gap between manual pipetting and complex liquid handling workstations, the system offered a cost-effective solution for tasks such as sample reformatting, plate preparation, and serial dilutions. This innovation was developed to enhance accessibility to automation and improve efficiency in diverse research environments.
• In June 2024, Beckman Coulter Life Sciences introduced the Biomek Echo One System, a solution engineered to accelerate high-throughput genomic sample preparation. This platform integrated the precise miniaturized dispensing capabilities of the Echo 525 Acoustic Liquid Handler with the robust automation of the Biomek i7 Hybrid Workstation. The system was designed to execute end-to-end library preparation workflows, covering steps such as extraction, fragmentation, ligation, and normalization in a single automated method. This launch aimed to provide laboratories with the flexibility and speed necessary to adapt to evolving genomic applications while ensuring consistent and reliable results.
• In February 2024, SPT Labtech announced the launch of firefly+, an advanced expansion of its genomics liquid handling platform designed to streamline automated sample preparation. This new system integrated an on-deck thermocycler and enhanced labware capacity, enabling fully hands-free workflows for next-generation sequencing (NGS) library preparation. The platform combined multiple functionalities, including pipetting, non-contact dispensing, shaking, and incubating, into a single compact unit. By utilizing an internal robotic gripper to transfer materials between modules, the solution allowed researchers to maximize walk-away time and focus on critical data analysis rather than manual liquid handling tasks.

Key Market Players

• Agilent Technologies, Inc.
• Aurora Biomed Inc.
• Danaher Corporation
• F. Hoffmann-La Roche Ltd
• Metrohm AG
• Mettler-Toledo International Inc
• MGI Tech Co., Ltd.
• Promega Corporation
• QIAGEN N.V.
• Revvity, Inc.

By Application	By Product Type	By End-User	By Region
Research and Development Diagnostics	Kits and Consumables Instruments	Biotechnology and Pharmaceutical Companies Clinical and Diagnostic Laboratories Academic and Research Institutions	North America Europe Asia Pacific South America Middle East & Africa

Report Scope:

In this report, the Global Automated Sample Preparation Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Automated Sample Preparation Market, By Application:

• Research and Development
• Diagnostics

• Automated Sample Preparation Market, By Product Type:

• Kits and Consumables
• Instruments

• Automated Sample Preparation Market, By End-User:

• Biotechnology and Pharmaceutical Companies
• Clinical and Diagnostic Laboratories
• Academic and Research Institutions

• Automated Sample Preparation Market, By Region:

• North America
• United States
• Canada
• Mexico
• Europe
• France
• United Kingdom
• Italy
• Germany
• Spain
• Asia Pacific
• China
• India
• Japan
• Australia
• South Korea
• South America
• Brazil
• Argentina
• Colombia
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE