United States Oncology Information Systems Market By Products & Services (Software, Professional Services), By Application (Medical Oncology, Radiation Oncology, Surgical Oncology), By End Use (Hospitals & Diagnostic Imaging Centers, Ablation Care Centers and Cancer Care Centers, Government Institutions, Research Facilities), By Region and Competition, Forecast & Opportunities, 2020-2030F

Market Overview

The United States Oncology Information Systems Market was valued at USD 912.11 Million in 2024 and is expected to reach USD 1404.16 Million by 2030 with a CAGR of 7.43%. The United States Oncology Information Systems (OIS) Market is witnessing significant transformation driven by the rising complexity of cancer care and the growing emphasis on streamlining clinical workflows. Oncology information systems play a crucial role in managing patient data, treatment planning, and care coordination, enabling healthcare providers to deliver accurate and timely interventions. These systems integrate medical imaging, chemotherapy planning, radiation therapy, and electronic health records (EHRs) into a unified platform, helping oncologists make informed decisions. As cancer continues to be a leading cause of mortality in the country, healthcare institutions are increasingly investing in advanced IT systems to support multidisciplinary treatment approaches and improve patient outcomes.

One of the primary growth drivers for the market is the rising incidence of various cancer types, necessitating advanced tools for diagnosis, treatment planning, and follow-up care. The increasing demand for precision oncology and personalized treatment regimens has accelerated the adoption of data-driven solutions like OIS. Integration of artificial intelligence (AI), machine learning, and predictive analytics in these systems is enabling clinicians to identify patterns and tailor treatments to individual patient profiles. Moreover, the shift toward value-based care models and regulatory pressure to digitize healthcare systems are encouraging hospitals and cancer centers to deploy robust oncology information platforms. These systems not only improve clinical accuracy but also support administrative functions such as billing, scheduling, and compliance management.

Despite strong growth prospects, the market faces several challenges. High implementation and maintenance costs of oncology information systems can be a barrier for smaller practices and rural healthcare centers. Integration of OIS with legacy hospital information systems remains complex, often requiring significant time and technical expertise. Concerns related to data privacy, system interoperability, and cybersecurity continue to impact adoption rates. Limited technical training and resistance to transitioning from traditional paper-based workflows to digital platforms may also hinder effective system utilization. As cancer treatment evolves and patient expectations rise, overcoming these challenges will be essential to unlocking the full potential of oncology information systems in the U.S. healthcare landscape.

Key Market Drivers

Increasing Cancer Incidence and Rising Patient Load

The increasing incidence of cancer in the United States significantly drives the demand for Oncology Information Systems (OIS), which are essential for managing the complexities of cancer care. In 2024, approximately 2,001,140 new cancer cases were projected, encompassing major types such as prostate, breast, lung, and colorectal cancers. This surge in cases necessitates advanced digital solutions to handle the growing volume of patient data and treatment information efficiently.

OIS platforms are pivotal in streamlining workflows, enhancing clinical decision-making, and ensuring accurate documentation across various stages of cancer treatment. They facilitate real-time access to patient records, support multidisciplinary collaboration, and integrate with other healthcare systems, thereby improving overall care coordination and patient outcomes. The complexity of modern cancer therapies, including personalized medicine and immunotherapy, further underscores the need for sophisticated information systems that can manage diverse treatment modalities and track patient responses effectively.

As the cancer burden continues to rise, healthcare providers are increasingly adopting OIS to optimize resource utilization, reduce treatment delays, and maintain high standards of care. These systems not only support clinicians in delivering precise and timely treatments but also assist in meeting regulatory requirements and participating in value-based care initiatives. The escalating incidence of cancer, coupled with the need for efficient and coordinated care, positions OIS as a critical component in the evolving landscape of oncology healthcare delivery.

Advancements in Digital Health and Healthcare IT Infrastructure

Advancements in digital health and healthcare IT infrastructure are crucial drivers of growth in the United States Oncology Information Systems (OIS) Market. According to the National Cancer Institute (NCI), as of 2023, nearly 1.9 million new cancer cases are expected to be diagnosed annually in the U.S., highlighting the urgent need for efficient oncology management tools to handle this patient volume. The complexity of cancer care requires seamless data integration and real-time communication across multidisciplinary teams, which modern OIS platforms are designed to provide.

The adoption of cloud computing and interoperable electronic health records (EHRs) has significantly enhanced data sharing capabilities within oncology care. The Office of the National Coordinator for Health Information Technology (ONC) reports that in 2023, approximately 90% of hospitals had adopted certified EHR technology, a critical foundation for deploying advanced oncology information systems. These integrated systems support personalized treatment planning by consolidating clinical data, imaging, and laboratory results, enabling clinicians to make data-driven decisions quickly and accurately.

Government initiatives such as the 21st Century Cures Act promote interoperability and patient access to electronic health data, further accelerating OIS adoption. The U.S. Department of Health and Human Services (HHS) continues to invest in cybersecurity and infrastructure modernization to protect sensitive patient information, addressing regulatory compliance challenges. Additionally, AI-driven analytics within OIS platforms are helping predict patient responses and optimize treatment regimens, reducing errors and improving outcomes. The ongoing digital transformation in healthcare IT is thus a fundamental factor driving the widespread implementation of oncology information systems across the country.

Rising Regulatory and Quality Reporting Requirements

The United States Oncology Information Systems (OIS) Market is significantly driven by increasing regulatory and quality reporting requirements. In July 2023, the Centers for Medicare & Medicaid Services (CMS) launched the Enhancing Oncology Model (EOM), a five-year voluntary payment model aimed at improving care coordination and reducing costs for Medicare beneficiaries undergoing systemic chemotherapy. As of June 2023, 67 oncology physician group practices, representing over 600 sites across 37 states, participated in the EOM, with plans to expand in July 2025. This model emphasizes the use of certified electronic health record technology, evidence-based guidelines, and electronic patient-reported outcomes, all of which require robust OIS platforms to ensure compliance and facilitate data reporting.

Simultaneously, the Merit-based Incentive Payment System (MIPS) under the Quality Payment Program (QPP) continues to mandate quality reporting for clinicians. In 2024, CMS adopted 198 quality measures for MIPS, with 16 MIPS Value Pathways (MVPs) introduced to streamline reporting by grouping measures relevant to specific specialties, including oncology. These developments necessitate advanced OIS solutions capable of aggregating and reporting data efficiently to meet performance benchmarks and secure reimbursement.

Collectively, these regulatory initiatives underscore the critical role of OIS in enabling healthcare providers to navigate complex reporting requirements, enhance care delivery, and maintain financial viability in an increasingly value-based healthcare landscape.

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Key Market Challenges

High Implementation and Maintenance Costs

High implementation and maintenance costs present significant challenges for the United States Oncology Information Systems (OIS) Market. Deploying sophisticated oncology information systems requires substantial upfront investment in software licenses, hardware infrastructure, and integration with existing healthcare IT systems. For many healthcare providers, especially smaller hospitals and outpatient centers, these initial expenses can be prohibitive. The cost of customizing OIS to meet the specific needs of oncology departments, including compliance with regulatory standards and interoperability requirements, further escalates the financial burden. This often leads to delayed adoption or reliance on outdated legacy systems that lack advanced functionalities.

Once implemented, ongoing maintenance and support costs continue to strain budgets. Regular software updates, system upgrades, and cybersecurity measures demand continuous financial and technical resources. Ensuring system reliability and minimizing downtime is critical in oncology care, where timely access to patient data can directly impact treatment outcomes. Healthcare organizations must invest in skilled IT personnel or outsource these services, which adds to operational expenses. The complexity of maintaining data security and patient privacy in oncology information systems necessitates robust security protocols, further increasing maintenance costs.

The financial burden associated with OIS implementation and upkeep can also affect return on investment (ROI) timelines. Many providers face challenges in quantifying the immediate benefits of OIS, such as improved workflow efficiencies and patient outcomes, making it difficult to justify large expenditures. Budget constraints and competing priorities within healthcare organizations limit funds available for technology upgrades, slowing the overall market growth. These cost-related challenges underscore the need for more cost-effective, scalable OIS solutions and financial models that support wider adoption, especially among smaller and mid-sized healthcare providers. Without addressing these financial barriers, the United States Oncology Information Systems Market may experience uneven growth and limited penetration across all care settings.

Integration Issues with Legacy Systems

Integration issues with legacy systems pose significant challenges for the United States Oncology Information Systems (OIS) Market. Many healthcare providers operate with a variety of outdated or disparate IT infrastructures that were not originally designed to support the complex needs of oncology information management. These legacy systems often lack compatibility with modern OIS platforms, creating barriers to seamless data exchange and communication across departments. The inability to integrate oncology software with existing electronic health records (EHR), laboratory information systems, and radiology systems can result in fragmented workflows and data silos. This fragmentation limits the ability to obtain a comprehensive view of a patient’s treatment journey, which is critical for making informed clinical decisions.

Healthcare providers face technical hurdles when attempting to connect new OIS solutions with legacy applications, as differences in data formats, communication protocols, and software architectures require extensive customization and resource investment. This process can be time-consuming and costly, straining IT budgets and delaying the benefits that OIS platforms are meant to deliver. Poor integration also increases the risk of data errors, duplication, or loss, which can compromise patient safety and treatment effectiveness. Staff training becomes more complicated when multiple, non-interoperable systems must be navigated simultaneously, potentially leading to workflow inefficiencies and increased administrative burden.

The challenge extends beyond technology to organizational readiness, as some healthcare facilities may lack the expertise or strategic vision to execute successful integration projects. Resistance to change from clinical and administrative staff accustomed to legacy systems can further slow adoption and optimal use of new oncology information technologies. Regulatory compliance requirements for data security and patient privacy add another layer of complexity to integration efforts, requiring thorough validation and testing to meet healthcare standards.

Key Market Trends

Growing Adoption of Cloud-Based Oncology Information Systems

​The growing adoption of cloud-based oncology information systems (OIS) is a significant trend transforming the United States Oncology Information Systems Market. Cloud technology offers healthcare providers scalable, flexible, and cost-effective solutions for managing complex oncology data, enabling seamless access to patient information from multiple locations. Cancer care often involves multidisciplinary teams working across different facilities, making centralized data storage and real-time access critical for effective coordination. Cloud-based OIS platforms facilitate this by allowing oncologists, radiologists, pharmacists, and other healthcare professionals to collaborate efficiently, improving decision-making and treatment planning.

Cloud deployment reduces the need for substantial upfront investment in physical IT infrastructure and ongoing maintenance costs, making these systems particularly attractive to smaller clinics and cancer centers that might lack extensive IT resources. The pay-as-you-go model typical of cloud services helps healthcare providers better manage budgets while benefiting from the latest software updates and security protocols without additional expenses. Cloud platforms also enhance data security and compliance with regulatory standards, as leading providers invest heavily in robust cybersecurity measures, disaster recovery, and encryption technologies to protect sensitive patient data.

Interoperability is another advantage of cloud-based oncology systems, as these platforms can easily integrate with existing electronic health records (EHRs), imaging systems, and laboratory information systems, creating a unified view of patient data. This integration supports value-based care initiatives by enabling detailed tracking of patient outcomes and treatment effectiveness. The scalability of cloud solutions allows healthcare organizations to adapt quickly to changing patient volumes and treatment complexities.

Patient engagement tools integrated into cloud OIS platforms further enhance communication by offering portals and mobile access to treatment plans, appointment scheduling, and educational resources. These capabilities improve patient satisfaction and adherence to therapy protocols. The growing focus on digital transformation within healthcare, combined with the operational and clinical benefits of cloud-based oncology information systems, is driving their rapid adoption across the U.S. market, shaping the future of cancer care delivery.

Increasing Role of OIS in Clinical Trials and Research

​The role of Oncology Information Systems (OIS) in clinical trials and research is becoming increasingly significant in the United States, reflecting a major trend shaping the market. Clinical trials in oncology are complex and require precise management of vast amounts of patient data, treatment protocols, and regulatory documentation. OIS platforms are evolving to support these requirements by integrating clinical trial management functionalities within their core systems. This integration allows for seamless identification and enrollment of eligible patients based on real-time clinical data, accelerating recruitment processes and improving trial efficiency.

Oncology information systems also facilitate comprehensive data collection and monitoring throughout the trial period, ensuring adherence to study protocols and enhancing data accuracy. The ability to link clinical trial data with routine patient care records creates opportunities for real-world evidence generation, which is increasingly valued by regulators and pharmaceutical companies for drug approval and post-market surveillance. Researchers benefit from the streamlined access to consolidated patient data, enabling more robust analysis and faster insights into treatment efficacy and safety.

The adoption of OIS in clinical research helps reduce administrative burdens and minimize errors, allowing healthcare providers to focus more on patient care and innovation. Integration with electronic health records and laboratory information systems supports comprehensive tracking of patient outcomes and adverse events. The use of these systems also promotes transparency and compliance with regulatory standards, which are critical for successful trial execution.

Incorporating research capabilities within oncology information systems fosters collaboration between clinical care teams and research organizations, driving advances in cancer treatment. This trend is further supported by growing investments in precision medicine and immunotherapy trials, which require highly detailed patient data management. The expanding role of OIS in clinical trials and research is transforming oncology care by bridging the gap between experimental therapies and routine clinical practice, positioning these systems as essential tools for innovation and improved patient outcomes.

Segmental Insights

Products & Services Insights

Based on the Products & Services, Software emerged as the dominant segment in the United States Oncology Information Systems Market in 2024. This is driven by the increasing demand for advanced digital solutions that streamline cancer care management. Oncology software plays a critical role in consolidating patient data, treatment planning, and clinical documentation, enabling healthcare providers to deliver more coordinated and precise care. The shift from manual and paper-based processes to electronic systems has accelerated the adoption of specialized oncology software, which offers features such as treatment protocol management, radiation therapy planning, chemotherapy scheduling, and integration with electronic health records (EHRs). Healthcare providers are prioritizing software solutions that facilitate real-time data access and enhance communication among multidisciplinary teams, including oncologists, radiologists, surgeons, and pharmacists. Software platforms equipped with clinical decision support tools and analytics capabilities are helping clinicians personalize treatment plans and improve patient outcomes.

Application Insights

Based on the Application, Medical Oncology emerged as the dominant segment in the United States Oncology Information Systems Market in 2024, reflecting the critical role these systems play in managing complex cancer treatments. Medical oncology primarily focuses on the diagnosis, treatment, and management of cancer using chemotherapy, targeted therapy, immunotherapy, and hormonal therapy. The increasing incidence of cancer and the growing demand for personalized treatment regimens have driven healthcare providers to adopt specialized information systems designed to support medical oncologists in delivering precise and effective care. OIS platforms tailored for medical oncology facilitate comprehensive management of patient records, treatment protocols, and medication schedules, enabling oncologists to monitor therapy responses and adjust treatments accordingly. These systems also assist in managing adverse effects and ensuring patient safety by integrating clinical decision support tools that flag potential drug interactions or contraindications. Real-time access to patient data improves coordination among multidisciplinary teams, which is essential for the complex nature of cancer care.

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Regional Insights

The Mid-West region emerged as the dominant region in the United States Oncology Information Systems Market in 2024. This is driven by several key factors unique to this geographic area. The region is home to a substantial number of large healthcare providers, cancer treatment centers, and research institutions that have invested heavily in digital health technologies to enhance oncology care. Many hospitals and clinics in the Mid-West have prioritized upgrading their healthcare IT infrastructure, adopting advanced OIS platforms to streamline cancer patient management and improve treatment outcomes. The demographic profile of the Mid-West, which includes a significant population with higher cancer incidence rates compared to national averages, has increased the demand for sophisticated oncology information systems. This demand is further supported by strong regional healthcare funding and government initiatives aimed at promoting health IT adoption and improving cancer care delivery. The presence of prominent technology vendors and collaborations between healthcare providers and software developers has accelerated the deployment of integrated OIS solutions across the region.

Recent Developments

• In November 2024, Ontada, a McKesson business specializing in community oncology real-world data, announced a strategic partnership with health data platform Datavant. The collaboration will integrate Ontada’s extensive real-world oncology data covering over 2.4 million patients and 80 tumor types from The US Oncology Network into Datavant’s health ecosystem. This partnership aims to accelerate life science companies’ access to critical insights, driving innovation in oncology and improving patient outcomes.
• In October 2024, GE HealthCare announced CareIntellect for Oncology, a cloud-based application that integrates multi-modal patient data into a single platform using generative AI to summarize clinical notes and reports. Designed to assist care teams in tracking disease progression and identifying treatment deviations, the tool supports prostate and breast cancer management. Scheduled for U.S. release next year, it consolidates structured and unstructured data, aids treatment response evaluation, clinical trial eligibility, and protocol adherence.
• In September 2024, Oracle launched CancerMPact Treatment Architecture Trends, a new cloud-based service that helps pharmaceutical companies analyze global cancer treatment patterns and assess the impact of market events like new drug approvals. This module, part of the broader CancerMPact platform, supports market sizing, strategic planning, and commercial opportunity identification across the U.S., Europe, Japan, and China. Oracle Health and Life Sciences emphasizes that CancerMPact enables critical insights for developing cancer therapies, continuing its two-decade partnership with leading pharmaceutical firms.
• In May 2024, Novartis announced the acquisition of Mariana Oncology for USD 1 billion upfront, with up to USD 750 million in potential milestone payments. Mariana Oncology, a biotechnology company specializing in innovative peptide-based radiopharmaceuticals for solid tumors, brings a strong pipeline and manufacturing capabilities. Its lead asset, MC-339, is a novel radioligand therapy targeting small cell lung cancer. The acquisition aims to combine Mariana’s radiopharmaceutical expertise with Novartis’ clinical development and commercialization strengths.
• In January 2024, Varian, a Siemens Healthineers company, and Nova Scotia Health announced a 10-year, CAD 175 million multi-disciplinary oncology partnership. The collaboration aims to enhance the cancer care pathway in Nova Scotia, a region with above-average cancer incidence, by accelerating patient progression from screening to survivorship. Leveraging Siemens Healthineers’ and Varian’s combined expertise, the partnership focuses on optimizing workflows, improving treatment precision, and increasing overall care efficiency across the healthcare system.

Key Market Players

• Elekta AB
• Accuray Incorporated
• RaySearch Laboratories
• Cerner Corporation
• BrainLab
• Philips Healthcare
• Prowess, Inc.
• DOSIsoft S.A.
• ViewRay Inc.
• MIM Software

Report Scope:

In this report, the United States Oncology Information Systems Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• United States Oncology Information Systems Market, By Products & Services:

o   Software

o   Professional Services

• United States Oncology Information Systems Market, By Application:

o   Medical Oncology

o   Radiation Oncology

o   Surgical Oncology

• United States Oncology Information Systems Market, By End Use:

o   Hospitals & Diagnostic Imaging Centers

o   Ablation Care Centers and Cancer Care Centers

o   Government Institutions

o   Research Facilities

• United States Oncology Information Systems Market, By Region:

o   North-East

o   Mid-West

o   West

o   South

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the United States Oncology Information Systems Market.

Available Customizations:

United States Oncology Information Systems Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

• Detailed analysis and profiling of additional market players (up to five).

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