Cold Chain Products Market for Plasma Fractionation - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Type (Ultra-low temperature freezer, Plasma freezer, Temperature monitoring devices, Plasma contact shock freezer, Blood transport boxes, Ice-lined refrigerator, Others), By End User (Blood collection centers and blood component providers, Hospitals and transfusion centers, Clinical research laboratories, Others), By Region, and By Competition, 2021-2031F

Forecast Period	2027-2031
Market Size (2025)	USD 308.44 Billion
CAGR (2026-2031)	12.87%
Fastest Growing Segment	Dairy & Frozen Desserts
Largest Market	North America
Market Size (2031)	USD 637.74 Billion

Market Overview

The Global Cold Chain Products Market will grow from USD 308.44 Billion in 2025 to USD 637.74 Billion by 2031 at a 12.87% CAGR. The Global Cold Chain Products Market comprises the integrated infrastructure, specialized transport, and thermal packaging solutions designed to maintain specific temperature conditions for perishable goods such as food, beverages, and pharmaceuticals. The primary drivers supporting market growth include the expanding volume of international trade in perishables and the fundamental rise in consumer demand for fresh, high-quality produce across diverse geographies. According to the Global Cold Chain Alliance, in 2025, member companies collectively operated 8.16 billion cubic feet of temperature-controlled capacity, representing an increase of more than 10 percent from the previous year. This expansion underscores the critical necessity for robust logistics networks to support the movement of temperature-sensitive commodities.

Despite this positive trajectory, a significant challenge impeding broader market expansion is the high operational expenditure associated with maintaining energy-intensive cold storage and transport systems. The volatility of energy prices and the substantial capital required for infrastructure development can severely strain profit margins, particularly in developing regions where power grids are unreliable. This financial burden often limits the ability of smaller logistics providers to upgrade their facilities, thereby creating bottlenecks in the global supply chain.

Key Market Drivers

The Rapid Expansion of Biopharmaceutical and Vaccine Logistics is a primary catalyst for market development, driven by the increasing complexity of biologic drugs and the necessity for precise thermal management. As pharmaceutical companies shift towards high-value, temperature-sensitive therapies such as cell and gene treatments, logistics providers are heavily investing in specialized infrastructure to ensure product integrity across global supply chains. This trend is evidenced by the resilience of the sector despite broader economic fluctuations. According to Cargo Airports & Airline Services, June 2025, in the 'Pharma air cargo tonnages rose by 2% in 2024' article, the worldwide transport of temperature-controlled pharmaceutical products returned to growth with a 2% increase in chargeable weight for the full year of 2024. This uptick highlights the sustained reliance on air freight for time-critical medical shipments, necessitating advanced active and passive packaging solutions to mitigate temperature excursions during transit.

Concurrently, the Increasing Globalization of Perishable Food Trade and Supply Chains significantly propels the industry, as developing nations modernize their food supply networks to reduce post-harvest losses and support export activities. This globalization demands robust storage and transport capabilities to handle longer transit times for fresh produce. A notable example of capital injection supporting this trade is seen in recent strategic developments in Africa. According to Ecofin Agency, October 2025, in the 'Maersk Expands Cold Storage in South Africa With $100M Investment' article, Maersk opened a new cold storage warehouse as part of a $100 million investment to modernize the country's cold-chain logistics network. Furthermore, the sheer scale of financial commitment in the sector is reflected in the performance of major market players. According to Lineage, Inc., February 2025, the company reported full-year 2024 revenue of $5.3 billion, underscoring the substantial monetary value generated by temperature-controlled warehousing services.

Download Free Sample Report

Key Market Challenges

The high operational expenditure required to maintain energy-intensive cold storage and transport systems presents a substantial barrier to broader market development. Maintaining precise temperature controls demands continuous energy consumption, exposing logistics providers to volatile utility prices. When these operational expenses rise, they disproportionately impact smaller regional providers who lack the financial reserves to absorb such costs or invest in modern, energy-efficient technologies. This financial disparity creates a polarized market where growth is concentrated among a few dominant entities, leaving gaps in service for underserved regions.

This consolidation limits the flexibility of the global supply chain and stifles competition. According to the Global Cold Chain Alliance, in April 2025, the top 25 global operators controlled 7.3 billion cubic feet of temperature-controlled capacity, highlighting a significant imbalance compared to the fragmented resources available to smaller competitors. Such market concentration indicates that high capital barriers are effectively preventing smaller players from scaling their operations. Consequently, this hampers the establishment of robust, capillary logistics networks needed to ensure consistent food security and pharmaceutical access in developing markets.

Key Market Trends

The Deployment of automated storage and retrieval systems (ASRS) in cold warehouses is a transformative trend reshaping inventory management by maximizing storage density and reducing reliance on manual labor in sub-zero environments. This automation addresses the critical industry shortage of skilled workforce while ensuring consistent product handling and reduced thermal fluctuations during retrieval processes, which is essential for maintaining the quality of sensitive perishables. According to WorldCargo News, November 2025, in the 'Maersk opens Shanghai centre, one of its largest warehousing investments globally' article, Maersk inaugurated a flagship facility featuring advanced ASRS and stacker cranes as part of a US$140 million investment to support customers in the Asia-Pacific region.

Concurrently, the transition towards biodegradable and reusable sustainable thermal packaging solutions is gaining momentum as logistics providers strive to minimize the environmental footprint of single-use plastics and expanded polystyrene (EPS). This shift is driven by stringent regulatory frameworks and corporate sustainability goals, pushing companies to adopt circular economy models for their temperature-controlled containers without compromising thermal performance. According to DCAT Value Chain Insights, April 2025, in the 'DHL Investing $2.2 Bn To Expand Healthcare & Life Sciences Logistics' article, DHL Group allocated a portion of its EUR 2 billion strategic investment plan specifically to enhancing both passive and active packaging capabilities for sustainability across its global network.

Segmental Insights

The Dairy & Frozen Desserts sector currently represents the fastest-growing segment in the Global Cold Chain Products Market. This rapid expansion is primarily driven by evolving consumer lifestyles and increasing urbanization, which have created a surge in global demand for convenience foods and ready-to-eat frozen treats. To support this growth, supply chains are heavily investing in infrastructure to maintain the strict temperature standards required by regulatory bodies such as the Food and Drug Administration. These mandates ensure product safety and extend shelf life, necessitating robust cold chain logistics to preserve quality throughout distribution.

Regional Insights

North America maintains a leading position in the Global Cold Chain Products Market, driven by established infrastructure for refrigerated storage and transportation. The region experiences consistent demand for temperature-controlled logistics from the pharmaceutical and processed food sectors. This dominance is reinforced by stringent regulatory requirements regarding product safety and quality, such as those enforced by the U.S. Food and Drug Administration (FDA). Consequently, businesses prioritize reliable cold chain solutions to ensure compliance and maintain product integrity, further solidifying the region's market authority.

Recent Developments

• In August 2025, A.P. Moller - Maersk announced new strategic investments in cold chain infrastructure and technology to support agricultural exporters in the Asia-Pacific region. The logistics company unveiled several service updates, including the "Durian Express," a specialized multimodal solution combining ocean, rail, and truck transport to accelerate the delivery of fresh produce from Thailand to China. Furthermore, the company integrated advanced remote container management tools that allow for real-time temperature monitoring and adjustments. These developments were designed to navigate fragmented infrastructure challenges and reduce spoilage for sensitive cargo, ensuring better transparency and control throughout the supply chain.
• In October 2024, Copeland introduced its latest ZB refrigeration scroll compressor technology at the Refcold event in India. This new product line was designed to offer enhanced reliability for medium and high-temperature applications, delivering an average efficiency improvement of up to 8% compared to existing models. The company also showcased its scroll inverter solutions intended to support solar and renewable-powered cold rooms, addressing the needs of remote farms with limited grid access. These innovations were presented as part of Copeland's strategy to improve energy efficiency and reduce operational costs for customers in the dairy, seafood, and food retail sectors operating in tropical climates.
• In September 2024, Carrier Transicold commercially launched a new version of its Vector HE 19 refrigeration unit during the IAA Transportation exhibition in Hanover, Germany. This advanced system for semi-trailers was engineered to utilize a refrigerant with low global warming potential and is fully compatible with hydrogenated vegetable oil and B100 biofuels. The product launch aimed to significantly reduce carbon dioxide emissions in the cold chain logistics sector while maintaining high performance standards. The company highlighted that this development would support the transport sector's decarbonization goals by providing a sustainable, energy-efficient alternative to traditional diesel-powered refrigeration units for international trucking fleets.
• In April 2024, CSafe expanded its portfolio of active and passive temperature-controlled shipping solutions by launching three new technologies at a major logistics event in Lyon, France. The company introduced its Multi-Use Dewars, part of the CGT Cryo Series, which were designed to serve the cell and gene therapy market by maintaining extremely low temperatures of -150°C or colder. Additionally, CSafe released the Connect Control Tower, a white-glove monitoring service that provides real-time visibility into critical shipping data such as GPS location and cargo temperature. The third innovation, Silverpod MAX RE, was debuted as a reusable shipping solution aimed at helping pharmaceutical clients meet their sustainability targets.

Key Market Players

• Thai Max Cold Storage Co. Ltd
• Nichirei Corporation
• Americold Reality Trust Inc.
• Nippon Express Co. Ltd
• John Swire & Sons (H.K.) Ltd
• Interstate Cold Storage Inc.
• Agility Holdings Inc.
• Snowman Logistics Ltd.
• JWD InfoLogistics Public Company Limited
• Burris Logistics

By Type	By End User	By Region
Ultra-low temperature freezer Plasma freezer Temperature monitoring devices Plasma contact shock freezer Blood transport boxes Ice-lined refrigerator Others	Blood collection centers and blood component providers Hospitals and transfusion centers Clinical research laboratories Others	North America Europe Asia Pacific South America Middle East & Africa

Report Scope:

In this report, the Global Cold Chain Products Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Cold Chain Products Market, By Type:

• Ultra-low temperature freezer
• Plasma freezer
• Temperature monitoring devices
• Plasma contact shock freezer
• Blood transport boxes
• Ice-lined refrigerator
• Others

• Cold Chain Products Market, By End User:

• Blood collection centers and blood component providers
• Hospitals and transfusion centers
• Clinical research laboratories
• Others

• Cold Chain Products Market, By Region:

• North America
• United States
• Canada
• Mexico
• Europe
• France
• United Kingdom
• Italy
• Germany
• Spain
• Asia Pacific
• China
• India
• Japan
• Australia
• South Korea
• South America
• Brazil
• Argentina
• Colombia
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE