Vitamin B9 Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Sales Channel (Direct, Indirect), By End Use (Pharmaceutical, Food, Animal Feed ,Cosmetic & Personal Care, Others), By Region and Competition, 2020-2030F

Market Overview

Global Vitamin B9 Market was valued at USD 87.10 Million in 2024 and is expected to reach USD 106.91 Million by 2030 with a CAGR of 2.45%. Vitamin B9 plays a vital role in DNA synthesis, red blood cell formation, and fetal development, making it a crucial nutrient across all age groups, especially among pregnant women. One of the primary drivers of the market is the growing emphasis on preventive healthcare. Consumers are increasingly turning to vitamin supplements to manage deficiencies and support long-term well-being. As a result, the demand for Vitamin B9-enriched supplements has surged, particularly in developed regions such as North America and Europe. Additionally, the rising incidence of anemia and neural tube defects in newborns has prompted governments and healthcare providers to promote folic acid supplementation, further boosting market growth.

Despite promising growth, the market faces several challenges, including regulatory hurdles and the risk of excessive intake leading to potential side effects. Additionally, fluctuating raw material prices and the high cost of advanced delivery technologies may pose constraints for small and mid-sized players. Strategic collaborations, investment in R&D, and geographic expansion into underserved markets are likely to define the competitive landscape in the coming years.

Key Market Drivers

Growth in Pharmaceutical Industry

The rapid expansion of the pharmaceutical industry is a significant catalyst propelling the growth of the global Vitamin B9 (folic acid) market. The global pharmaceutical industry has witnessed substantial expansion over the past two decades, reaching approximately USD 1.6 trillion in revenue by 2023. This level of growth has positioned the industry’s market size on par with the gross domestic products (GDPs) of major economies such as Spain, Mexico, and Australia. As healthcare systems worldwide place increasing emphasis on disease prevention, prenatal care, and nutritional supplementation, the demand for Vitamin B9 in pharmaceutical formulations continues to rise. This trend is particularly pronounced in developing regions where access to fortified foods is limited, making pharmaceutical-grade supplements a critical source of essential micronutrients.

Vitamin B9 plays a pivotal role in cell division, DNA synthesis, and red blood cell formation, making it indispensable in various therapeutic areas. In 2021, Southern Health Foods Pvt Ltd., an Indian company, expanded into the women’s health beverage segment with the introduction of Manna iStrong. This iron-fortified multigrain instant drink mix is formulated with super grains and delivers 100% of the Recommended Dietary Allowance (RDA) for Vitamins B12, C, and B9. Its use is especially prevalent in prenatal supplements aimed at preventing neural tube defects in newborns, thereby fueling consistent demand across obstetric and gynecological applications. Furthermore, the rising incidence of anemia, cardiovascular conditions, and cognitive disorders has intensified the inclusion of folic acid in pharmaceutical products tailored for adults and elderly populations.

Growth in Food Industry

The global vitamin B9 market is experiencing a significant surge, largely propelled by the rapid expansion of the food industry. In 2025, the global food market is projected to generate revenue of USD 9.43 trillion. Among its various segments, meat represents the largest share, with an estimated market value of USD 1.55 trillion. As food manufacturers increasingly focus on nutritional fortification to meet evolving consumer preferences for health-enhancing products, demand for vitamin B9 (also known as folate or folic acid) has escalated across various food segments. This trend is particularly prominent in the fortified foods and functional beverages sector, where vitamin B9 is being incorporated to address nutritional deficiencies and support overall wellness.

The rising consumer awareness of the health benefits associated with folic acid—such as improved fetal development, cardiovascular health, and cognitive function—has led to an increased preference for vitamin-enriched food products. Governments and health organizations worldwide are also playing a pivotal role by mandating or encouraging folic acid fortification in staple foods such as flour, rice, and cereals to combat neural tube defects and other folate-related health issues. This regulatory push, in tandem with a growing emphasis on preventive healthcare, is contributing to sustained demand for vitamin B9 in the food industry.

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Key Market Challenges

Raw Material Supply Disruptions

One of the critical challenges facing the global Vitamin B9 (folate/folic acid) market is the disruption in the supply of key raw materials. The production of Vitamin B9 relies heavily on a range of chemical intermediates and specialty ingredients, many of which are sourced from a limited number of global suppliers. Any instability in the supply chain be it due to geopolitical tensions, trade restrictions, natural disasters, or pandemic-related lockdowns can severely impact production continuity and cost efficiency.

In recent years, global supply chain vulnerabilities have become more apparent, particularly due to the COVID-19 pandemic, which exposed the fragility of international logistics and manufacturing networks. The reliance on specific countries, especially China and India, for bulk intermediates and active pharmaceutical ingredients (APIs) has further amplified the risk. Any regulatory tightening, environmental compliance crackdowns, or export limitations in these key manufacturing hubs can lead to material shortages and production delays.

Key Market Trends

Increasing Demand for Dietary Supplements

The rising consumer inclination toward preventive healthcare and wellness has positioned dietary supplements as a key trend shaping the global Vitamin B9 (folic acid) market. With growing awareness of the importance of micronutrient intake, individuals across diverse age groups are turning to supplements to maintain overall health, bridge nutritional gaps, and mitigate the risk of chronic conditions. This shift in consumer behavior is driving robust demand for Vitamin B9 in the global nutraceutical sector.

Folic acid is recognized for its critical role in supporting cellular function, aiding red blood cell production, and facilitating healthy fetal development. As a result, it is a common component in multivitamin and prenatal supplement formulations. Merck has introduced a new dietary supplement, Arcofolin L-Methylfolate, aimed at combating folate deficiencies and reducing the risk of associated health conditions such as anemia, neural tube defects, and osteoporosis. This supplement features a biologically active form of vitamin B9, commonly referred to as folic acid, formulated for optimal bioavailability and efficient metabolism within the body. The widespread adoption of health-conscious lifestyles, particularly in North America, Europe, and emerging economies in Asia-Pacific, has contributed to a steady increase in the consumption of Vitamin B9-enriched dietary supplements.

Segmental Insights

Sales Channel Insights

Based on Sales Channel, Direct have emerged as the fastest growing segment in the Global Vitamin B9 Market in 2024. Direct application of Vitamin B9, such as in dietary supplements and pharmaceutical formulations, offers manufacturers precise control over dosage and formulation, which is highly valued in both clinical and consumer health settings. This direct incorporation enables targeted delivery of folic acid to address specific nutritional deficiencies and health conditions, driving strong demand from healthcare providers and end-users alike.

End Use Insights

Based on End Use, Cosmetic & Personal Care have emerged as the fastest growing segment in the Global Vitamin B9 Market during the forecast period. Increasing awareness about the importance of vitamins and nutrients in maintaining healthy skin has significantly boosted the adoption of Vitamin B9 in cosmetic formulations. Consumers are becoming more informed about the benefits of folate derivatives in promoting skin regeneration, reducing inflammation, and enhancing overall skin appearance, which has led to higher demand for products enriched with Vitamin B9. Vitamin B9, also known for its antioxidant and moisturizing properties, aligns well with consumer preferences for clean-label, nutrient-rich skincare products. This trend has encouraged manufacturers to innovate and introduce Vitamin B9-infused cosmetics, driving segment growth.

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Regional Insights

Based on Region, North America have emerged as the dominating region in the Global Vitamin B9 Market in 2024. The region benefits from well-established regulatory frameworks that mandate the fortification of staple foods with folic acid, effectively driving consistent demand across both consumer and industrial segments. Government initiatives aimed at preventing neural tube defects and promoting maternal health have further bolstered market growth by encouraging widespread adoption of Vitamin B9 supplements.

Recent Development

• In September 2024, German researchers introduced a two-stage bioreactor system designed to produce yeast enriched with protein and vitamin B9 (folate), a vital nutrient for cellular growth and metabolism. In the initial stage, the bacterium Thermoanaerobacter kivui converts hydrogen and carbon dioxide into acetate, a compound commonly found in vinegar. Subsequently, in the second stage, Saccharomyces cerevisiae (baker’s yeast) utilizes acetate and oxygen to synthesize protein and vitamin B9. The hydrogen and oxygen required for this process can be sustainably generated through water electrolysis powered by renewable energy sources such as wind turbines.
• In December 2024, the introduction of ACI Pure Fortified Rice marked a pivotal advancement in tackling the nutritional challenges prevalent in Bangladesh. By fortifying rice with vital nutrients, ACI Foods Limited – Rice Unit is making substantial progress in enhancing public health and fostering a healthier future for the nation. Fortified rice transcends being a basic staple; it represents a scientific breakthrough. Engineered to address micronutrient deficiencies, this product is enriched with essential vitamins and minerals. Notably, every 100 grams of ACI Pure Fortified Rice provides 130-190 mcg of Vitamin B9 (folic acid), which supports cell growth and helps reduce birth defects.
• In October 2024, BERLANDES, a leader in cellular regeneration and biotechnology, announced the launch of its latest innovation, the PCCIDINCT2 Ovarian Capsules. This groundbreaking product is designed to promote ovarian health and address prevalent reproductive concerns in women, drawing on decades of expertise in biological sciences. Distinct from competitors, the PCCIDINCT2 Core formula integrates the PCC1+OPC antioxidant complex to rejuvenate aging ovarian cells, a potent 40:1 inositol blend combined with vitamin B9 to regulate hormonal balance and alleviate PCOS symptoms, and the inclusion of Neumentix Spearmint extract to support emotional well-being. The formulation is thoughtfully developed to deliver a superior consumer experience.
• In April 2025, the Government of India launched the Anemia Mukt Bharat (AMB) strategy to reduce anemia among children and women, including pregnant and lactating mothers, using a life cycle approach. The program implements six interventions, including Prophylactic Iron and Folic Acid (IFA) supplementation: biweekly IFA syrup for children 6-59 months, pink tablets for children 5-9 years, and blue tablets for adolescents 10-19 years. The Department of Food and Public Distribution also supplies fortified rice enriched with iron, folic acid, and vitamin B12 through the Targeted Public Distribution System (TPDS), PM POSHAN, Integrated Child Development Services (ICDS), and other welfare schemes across all States and UTs to combat micronutrient deficiencies.

Key Market Players

• Anhui Xinhong Chemical Co., Ltd
• Changzhou Niutang Chemical Plant Co., Ltd.
• Zhejiang Shengda Bio-Pharm Co., Ltd.
• Xinfa Pharmaceutical Co., Ltd.
• Jiangxi Tianxin Pharmaceutical Co., Ltd.
• Hebei Jiheng (Group) Pharmaceutical Co., Ltd.

Report Scope

In this report, the Global Vitamin B9 Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Vitamin B9 Market, By Sales Channel:

o   Direct

o   Indirect

• Vitamin B9 Market, By End Use:

o   Pharmaceutical

o   Food

o   Animal Feed

o   Cosmetic & Personal Care

o   Others

• Vitamin B9 Market, By Region:

o   North America

§  United States

§  Canada

§  Mexico

o   Europe

§  France

§  United Kingdom

§  Italy

§  Germany

§  Spain

o   Asia Pacific

§  China

§  India

§  Japan

§  Australia

§  South Korea

o   South America

§  Brazil

§  Argentina

§  Colombia

o   Middle East & Africa

§  South Africa

§  Saudi Arabia

§  UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Vitamin B9 Market.

Available Customizations:

Global Vitamin B9 Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

• Detailed analysis and profiling of additional market players (up to five).

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