Global Oxygenators Market By Product Type (Bubble Oxygenator v/s Membrane Oxygenator), By Type (Adult Oxygenators v/s Pediatric Oxygenators), By Application (Respiratory, Cardiac, COVID-19, Others), By End User (Hospitals & Clinics, Ambulatory Care Centers, Others), By Region, Competition Forecast & Opportunities, 2021-2031F

Forecast Period	2027-2031
Market Size (2025)	USD 0.49 Billion
CAGR (2026-2031)	5.09%
Fastest Growing Segment	Membrane Oxygenator
Largest Market	Europe
Market Size (2031)	USD 0.66 Billion

Market Overview

The Global Oxygenators Market will grow from USD 0.49 Billion in 2025 to USD 0.66 Billion by 2031 at a 5.09% CAGR. Oxygenators are specialized medical devices utilized primarily during cardiopulmonary bypass surgeries and extracorporeal membrane oxygenation procedures to temporarily substitute the respiratory function of the lungs. These devices facilitate the essential exchange of gases by enriching venous blood with oxygen and removing carbon dioxide before returning it to the patient's arterial system. The market is fundamentally supported by the escalating global incidence of severe cardiovascular conditions and respiratory failures which necessitate invasive surgical interventions. According to the American Heart Association, in 2024, it was reported that cardiovascular disease accounted for approximately 19.91 million deaths globally, underscoring the critical and growing demand for effective cardiopulmonary support technologies.

Despite the strong demand, the sector faces a significant challenge regarding the stringent regulatory frameworks governing device approval and quality assurance. Manufacturers are required to navigate complex compliance standards and extensive clinical testing to ensure patient safety, which substantially prolongs product development cycles. These rigorous requirements increase operational costs and create high barriers to entry, potentially delaying the commercialization of new technologies and impeding the rapid expansion of the market.

Key Market Drivers

The Rising Prevalence of Cardiovascular and Respiratory Diseases serves as a primary engine for market growth, necessitating a higher frequency of invasive interventions such as coronary artery bypass grafting and heart valve repairs. As the burden of these chronic conditions intensifies, the volume of surgical procedures requiring temporary cardiopulmonary support has surged, directly increasing the utilization of oxygenators. This trend is substantiated by procedural data from major clinical registries; according to The Society of Thoracic Surgeons, in March 2025, the Adult Cardiac Surgery Database was reported to encompass more than 8.3 million cumulative procedures, highlighting the extensive scale of surgical demand. This sustained clinical activity translates into substantial financial performance for key manufacturers, verifying the market's upward trajectory. According to Terumo Corporation, in May 2025, the company reported an annual revenue of ¥1,036.2 billion for the fiscal year ended March 31, 2025, reflecting the robust commercial momentum driven by these essential cardiac and vascular therapies.

Concurrently, the Expanding Clinical Adoption of Extracorporeal Membrane Oxygenation (ECMO) significantly broadens the utilization of oxygenators beyond traditional theater settings into intensive care units. Advancements in device biocompatibility have allowed healthcare providers to deploy ECMO systems for longer durations in treating severe acute respiratory failure and cardiac arrest, thereby creating a distinct and rapidly growing revenue stream. The widening application of this life support modality is evidenced by recent global registry statistics. According to the Extracorporeal Life Support Organization, in April 2025, the registry had recorded a cumulative total of 245,291 extracorporeal life support runs, demonstrating the increasing integration of these advanced oxygenation technologies into standard critical care protocols for complex patient cases.

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Key Market Challenges

The Global Oxygenators Market is currently facing substantial headwinds due to the stringent regulatory frameworks governing device approval and quality assurance. While the clinical need for cardiopulmonary support is rising, the complex compliance standards required to bring these life-sustaining devices to market act as a significant bottleneck. Manufacturers must dedicate extensive resources to navigate these rigorous protocols, which significantly extends the timeline from product conception to commercial availability. This delay disrupts the supply chain and prevents advanced oxygenation technologies from reaching healthcare providers promptly.

The financial impact of these regulations creates a high barrier to entry that stifles broader market expansion. Companies are forced to absorb higher development costs for longer periods without generating revenue. According to MedTech Europe, in 2024, the average time to certification for medical devices under the current regulations was reported to be between 13 and 18 months. This prolonged cycle deters investment in new product development and disproportionately affects smaller innovators who lack the capital to sustain operations during such lengthy review periods, ultimately slowing the overall growth rate of the sector.

Key Market Trends

The Emergence of Smart Oxygenators with Integrated Sensor Monitoring is transforming the market by enhancing clinical decision-making during complex perfusion procedures. These systems incorporate real-time sensing capabilities directly into the device design, allowing for continuous feedback on critical parameters like oxygen saturation and line pressure without external probes. This integration streamlines perfusionist workflows and improves operational efficiency by reducing the equipment footprint in operating theaters. The commercial impact of such integrated systems is evident; according to LivaNova PLC, October 2024, in the 'Third-Quarter 2024 Results', Cardiopulmonary segment revenue increased by 15.6%, specifically driven by the sales of the Essenz Perfusion System and its associated consumables.

Simultaneously, the Adoption of Polymethyl Pentene (PMP) Hollow Fiber Technology is displacing traditional polypropylene membranes, particularly for extended life support. PMP fibers offer enhanced resistance to plasma leakage, enabling oxygenators to function effectively for days rather than hours, thereby supporting the growing need for long-duration extracorporeal membrane oxygenation (ECMO). This material advancement fuels demand for durable disposables even amidst broader supply chain fluctuations. According to Getinge, October 2024, in the 'Interim Report July-September 2024', the company observed particularly strong growth in consumables within the Cardiopulmonary business area, reflecting the sustained market reliance on these advanced oxygenation technologies for acute care therapies.

Segmental Insights

The Membrane Oxygenator segment currently represents the fastest-growing category within the global oxygenators market due to its superior safety profile compared to legacy bubble oxygenators. This growth is largely propelled by the technology's ability to minimize blood trauma and embolism risks during cardiopulmonary bypass surgeries. Additionally, the rising utilization of Extracorporeal Membrane Oxygenation for managing severe respiratory and cardiac failure has significantly amplified demand. Continued product clearances by the US Food and Drug Administration further validate the clinical preference for these devices, ensuring their sustained expansion across healthcare facilities worldwide.

Regional Insights

Based on insights from trusted market analysis, Europe stands as a leading region in the Global Oxygenators Market, driven by its sophisticated healthcare infrastructure and the high adoption rate of advanced life-support technologies. The region’s dominance is underpinned by a growing geriatric population and a rising prevalence of cardiovascular and respiratory diseases, which sustain a strong demand for cardiac surgeries and Extracorporeal Membrane Oxygenation (ECMO) procedures. Furthermore, Europe is home to major medical device manufacturers, ensuring a steady supply chain and continuous technological innovation. Strict adherence to safety frameworks, such as the European Medical Device Regulation, further solidifies the region’s market leadership by maintaining high product standards and fostering clinical confidence.

Recent Developments

• In August 2025, LivaNova initiated the commercial launch of its Essenz Perfusion System in China following approval from the National Medical Products Administration (NMPA). This launch marked a major expansion for the company into its second-largest global market for heart-lung machines. The Essenz system, which integrates a next-generation oxygenator and heart-lung machine with advanced data sensing capabilities, was designed to improve clinical workflows and patient safety during cardiopulmonary bypass procedures. The introduction of this technology into the Chinese market was a strategic move to address the region's rising volume of cardiac surgeries and the increasing need for sophisticated perfusion management tools.
• In February 2025, Getinge announced a significant strategic shift in its cardiovascular portfolio, deciding to phase out the production of its cardiopulmonary surgical perfusion products to concentrate resources on its Extracorporeal Membrane Oxygenation (ECMO) and Intra-Aortic Balloon Pump (IABP) segments. The company stated that this restructuring would allow for increased investment and research focus on high-growth areas within acute heart and lung support. By discontinuing legacy heart-lung machine production, Getinge aims to accelerate the development of innovative oxygenator technologies and strengthen its market position in advanced life-support solutions for critically ill patients.
• In October 2024, Xenios AG, a subsidiary of Fresenius Medical Care, introduced the Xenios 2.0, a next-generation extracorporeal life support (ECLS) console designed to meet the rigorous standards of the new European Medical Device Regulation (MDR). This advanced system was developed to provide comprehensive support for patients ranging from neonates to adults suffering from severe heart and lung failure. The launch highlighted significant improvements in device connectivity, user interface simplicity, and safety features, positioning the company to address the growing global demand for reliable and versatile ECMO therapies in critical care settings.
• In March 2024, Medtronic expanded its presence in the cardiac surgery landscape by acquiring MC3 Cardiopulmonary, a Michigan-based company specializing in the development of extracorporeal membrane oxygenation (ECMO) technologies. This strategic acquisition provided Medtronic with proprietary technology that had previously been distributed under its portfolio, specifically aiming to enhance its offerings in the extracorporeal life support market. The collaboration underscored Medtronic’s commitment to broadening its capabilities in treating severe cardiopulmonary conditions by integrating MC3's advanced manufacturing and research expertise directly into its operational structure, thereby securing a robust pipeline for future oxygenator and life-support system innovations.

Key Market Players

• Abbott Laboratories
• F. Hoffmann-La Roche Ltd.
• Thermo Fisher Scientific, Inc.
• Siemens Healthcare GmbH
• Bio-Rad Laboratories, Inc.
• Koninklijke Philips N.V.
• Toshiba Corporation
• Agilent Technologies, Inc.
• Illumina, Inc.
• Merck KGaADanaher Corporation

By Product Type	By Type	By Application	By End User	By Region
Bubble Oxygenator v/s Membrane Oxygenator	Adult Oxygenators v/s Pediatric Oxygenators	Respiratory Cardiac COVID-19 Others	Hospitals & Clinics Ambulatory Care Centers Others	North America Europe Asia Pacific South America Middle East & Africa

Report Scope:

In this report, the Global Oxygenators Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Oxygenators Market, By Product Type:

• Bubble Oxygenator v/s Membrane Oxygenator

• Oxygenators Market, By Type:

• Adult Oxygenators v/s Pediatric Oxygenators

• Oxygenators Market, By Application:

• Respiratory
• Cardiac
• COVID-19
• Others

• Oxygenators Market, By End User:

• Hospitals & Clinics
• Ambulatory Care Centers
• Others

• Oxygenators Market, By Region:

• North America
• United States
• Canada
• Mexico
• Europe
• France
• United Kingdom
• Italy
• Germany
• Spain
• Asia Pacific
• China
• India
• Japan
• Australia
• South Korea
• South America
• Brazil
• Argentina
• Colombia
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE