Organ Transplant Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product (Tissue Products, Organ Preservation Products, Transplant Diagnostics, Immunosuppressant Drugs, Others), By Application (Organ Transplantation, Tissue Transplantation), By Type of Transplant (Autograft, Allograft, Others), By End User (Hospitals, Transplant Centers, Others), By Region and Competition, 2020-2030F

Market Overview

Global Organ Transplant Market was valued at USD 14.56 Billion in 2024 and is anticipated to project impressive growth in the forecast period with a CAGR of 8.93% through 2030F. The organ transplantation market primarily deals with the procedure of transplanting organs. Organ transplantation is a medical intervention wherein an organ is extracted from one body and implanted into another to address organ failure, fill a void, or replace a damaged or missing organ. This procedure is commonly employed to treat organ failure in vital organs such as the lungs, kidneys, liver, and others. Candidates most commonly considered for organ transplantation are individuals with brain death yet possessing healthy organs that can potentially save another person's life. Prior to undertaking this intricate procedure, obtaining the consent of the patient or their family is of utmost importance, as organ harvesting without consent is deemed an illegal and reprehensible act. For instace, as of February 2024, the Health Resources & Services Administration reported approximately 103,223 individuals including men, women, and children on the U.S. national organ transplant waiting list. This high demand for transplant procedures in major countries is expected to significantly drive market growth during the forecast period. 

Key Market Drivers

Growing Organ Failures and Organ Donations Procedure

The demand for organ transplantation has been on the rise globally in the past decade. This can be attributed to the increased prevalence of vital organ failure, higher success rates of transplantation, and improved post-transplant outcomes. The incidence of organ failure has also increased due to factors such as alcohol consumption, substance abuse, and unhealthy diets leading to chronic diseases affecting vital organs like lungs, kidneys, and liver. Organ transplantations have become a life-saving measure for patients, which is driving the growth of the transplantation market. The technological advancements in transplantation methods are contributing to the overall market revenue growth.  The increasing prevalence of chronic diseases leading to organ failures is a significant driver for market growth. The global rise in organ donation has also influenced people to opt for organ transplantation, thereby accelerating market expansion. The the excessive consumption of alcohol and unhealthy dietary habits among the population contribute to organ failure, further augmenting market growth. The proliferation of personal insurance, coupled with lifestyle factors contributing to the burden of illness, is projected to bolster market growth. The procurement and preservation of organs and tissues are expected to provide further impetus to market expansion. In March 2023, the Pan American Health Organization (PAHO) and Spain’s Ministry of Health signed an agreement aimed at strengthening the organ donation and transplantation sector in the United States. This collaboration seeks to enhance healthcare systems, share best practices, and promote policies that increase organ availability, ultimately addressing the growing demand for transplants across the country. This strategic partnership highlights the importance of international cooperation in overcoming organ shortages and improving transplant outcomes.

Increase In the Demand for Organs for Transplant

The global surge in demand for transplant organs can be attributed to the rising incidence of acute diseases, leading to an increase in organ failures. For instance, end-stage renal disease, primarily caused by diabetes and high blood pressure, necessitates kidney transplants or dialysis as the sole treatment options to sustain patient life. For instance, According to data from the U.S. Health Resources & Services Administration and Organ Donation Statistics, over 46,000 organ transplant procedures were successfully performed in the United States in 2023. This milestone reflects ongoing advancements in medical technology and growing awareness about organ donation, underscoring the country’s commitment to addressing transplant needs and improving the quality of life for patients with organ failure. As per the U.S. Department of Health & Human Services, approximately 121,678 patients were awaiting organ transplants in the U.S. in 2019. Consequently, there is a substantial demand for advanced transplantation products to address organ failure. To address this challenge, the U.S. government's Health Resources and Services Administration (HRSA) launched an initiative in March 2023 aimed at modernizing the transplantation network and organ procurement. This effort emphasizes the dissemination of new organ donor and transplant data.

Increasing Number of Tissue Banks

Tissue banks have been known to store biomedical tissues under cryogenic conditions. As the demand for tissue transplantation increases, so does the demand for tissue banks that offer a wide range of services including donor assessment, processing, recovery, storage, labeling, and delivery of tissues. These banks primarily rely on low temperature storage to maintain tissues at optimal conditions. The rise in burn injuries has led to a significant demand for tissue banks that specialize in the retrieval and aseptic storage of skin for donation. The technological advancements such as centrifuges and cryopreservation systems have greatly improved the efficiency of tissue preservation. The computerized support systems equipped with advanced hardware and software have made it easier to maintain and manage tissues with high efficiency. These developments have made the storage and retrieval of organs relatively more convenient, thereby driving the growth of the market.

Technological Advancements in Organ Transplant Methods

Technological advancements in the field of 3D bioprinting are playing a significant role in driving the adoption of organ transplantation. The continuous developments in PCR technique, including enhancements in system design and advanced assays, have greatly improved the precision and effectiveness of tissue typing. The pioneering technique known as desensitization, developed by John Hopkins University School of Medicine, has revolutionized kidney transplantation by enabling the use of organs from any donor. The therapeutic hypothermia, utilizing targeted temperature management, has emerged as a critical factor in organ transplantation, safeguarding neurological functions in patients with cardiac arrest, asphyxia, and stroke. The introduction of these advanced techniques has contributed to the growth of the global transplantation market, leading to an increase in the number of organ transplant procedures worldwide

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Key Market Challenges

Transplant Rejection

Transplant rejection is a complex process whereby the recipient's immune system mounts an attack against the transplanted organ or tissue, recognizing it as foreign. Three types of rejections are commonly observed: hyper-acute rejection, acute rejection, and chronic rejection. Despite meticulous donor matching, tissue typing, and the use of immunosuppressive medications, instances of transplant rejection still occur, leading to organ failure. Non-compliance with immunosuppressive drugs remains a significant contributing factor to rejection. Complications that may arise from transplant rejection include certain types of cancers, infections, impaired function of the transplanted tissue or organ, and adverse effects due to incorrect medication dosages. According to the Organ Procurement and Transplantation Network, approximately 4% of deceased donor kidney transplants experience failure within one year, while living donor kidney transplant recipients face a 14% failure rate at five years post-transplant. Consequently, these factors pose challenges to the growth of the market.

Shortage of Organ Donors

According to the Living Kidney Donors Network, the global number of kidney transplant recipients exceeded 90,000 in 2017, and this figure is projected to rise in the near future. Traditionally, organs are procured from deceased patients who have experienced brain injury or stroke. However, the prevalence of smoking, alcohol consumption, and drug abuse has led to a decline in the pool of healthy individuals suitable for organ donation. Consequently, there is an escalating number of patients on transplant waiting lists, as the availability of suitable organs for transplantation remains limited. The lack of awareness surrounding organ donation has emerged as a significant factor impeding market growth. The ethical and cultural considerations pose substantial challenges in the transplantation market. Developing and underdeveloped nations often exhibit a lack of awareness regarding organ donation, contributing to hesitance among potential organ donors. Cultural and social stigmas, as well as religious and customary beliefs, frequently discourage organ donation among families. These factors collectively hinder the market's growth prospects.

Key Market Trends

Advances In the Technology and Development

Advances in technology and development have the potential to significantly boost the demand for organ transplants in the future by addressing some of the challenges and limitations currently faced by the field. Progress in technology and advancements in the medical field have facilitated the transplantation of vital organs like the heart, kidney, liver, lungs, and various other organs. Key technical achievements encompass the development of vascular anastomosis techniques, effective management of the immune response through chemical immunosuppressants, and the formulation of preservation solutions. For instance, in June 2023, 3D BioFibR introduced μCollaFibR, a bio-ink additive, and CollaFibR 3D scaffold, an advanced collagen fiber product designed for bioprinting tissue and organ models. These innovations aim to enhance the precision and functionality of bioprinted structures, supporting the development of next-generation solutions in regenerative medicine and transplantation. 

These advancements can improve organ availability, enhance transplant success rates, and expand the possibilities for transplantation. Technology has the potential to improve organ preservation and transportation methods, enabling organs to remain viable for longer periods before transplantation. This can lead to more efficient organ allocation, reduced wastage, and broader access to viable organs. Advances in bioprinting and tissue engineering are enabling the creation of bioengineered organs and tissues in the laboratory. This technology has the potential to address organ shortages by producing organs on demand, reducing the dependency on donor organs. Developments in immunosuppressive medications can lead to more targeted and effective treatments that minimize the risk of organ rejection. Improved immunosuppressive protocols can increase the success rate of transplant surgeries and reduce the need for high doses of medication. Research into xenotransplantation, the transplantation of organs from animals to humans, holds the potential to overcome the shortage of human donor organs. Advances in genetic editing and immunomodulation are making xenotransplantation more feasible and safer.

Advancements in Regenerative Medicine

Regenerative therapies and tissue engineering are likely to revolutionize organ transplantation by providing alternatives to traditional donor organs. The development of bioengineered tissues, organoids, and lab-grown organs could increase the availability of transplantable tissues.  Scientists are working on creating functional tissues in the laboratory using a combination of cells, scaffolds, and growth factors. These bioengineered tissues could be used to repair damaged organs, restore function, or provide temporary support while waiting for a suitable donor organ. Organoids are miniature, simplified versions of organs grown in the lab from stem cells. They closely mimic the structure and function of actual organs, making them valuable for studying diseases, testing drug responses, and potentially serving as transplantable tissues in the future. Bioengineered tissues and organs can potentially be created using a patient's own cells, reducing the risk of rejection and the need for immunosuppressive medications.

Segmental Insights

Application Insights

The organ transplant segment recorded the highest revenue share in 2024. This can be attributed to the increasing demand for organ transplantation worldwide, driven by a rise in cases of organ failure resulting from heavy alcohol consumption and an unhealthy lifestyle. The continuous technological advancements by key players and healthcare professionals have improved the success rate and post-transplant prognosis, thereby fuelling the revenue growth of this segment. On the other hand, the tissue transplant segment is expected to exhibit a steady growth rate during the forecast period. There is a significant demand for transplants of cornea, bones, skin, nerves, tendons, veins, and heart valves, especially for individuals affected by burns and accidents.

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Regional Insights

Based on regional analysis, North America accounted for the largest share of revenue in 2024. The market's growth in this region is driven by continuous development of innovative transplantation products, a well-developed healthcare system, and increased personal health expenditure by the population. The strong presence of various large-scale biotechnology and medical device companies is expected to further drive revenue growth in North America. The supportive government policies in Canada and the US contribute to the market's growth in this region. The market in the Asia Pacific region is projected to experience a faster revenue growth rate during the forecast period. The increasing prevalence of chronic diseases and the rise in road accidents leading to permanent organ damage are major factors driving revenue growth in this region. The continuous advancements in transplantation technology by major players in countries within this region contribute to the revenue growth of the Asia Pacific transplantation market. Meanwhile, the European market is expected to maintain a steady high revenue growth rate during the forecast period. The increasing consumption of drugs and alcohol resulting in organ damage, combined with the strong presence of major market players and availability of skilled doctors, are driving the revenue growth of the market in the region.

Recent Developments

• In April 2023, surgeons in Spain successfully performed the world’s first robotic lung transplant using a surgical robot known as Da Vinci. This groundbreaking procedure marked a significant advancement in transplant surgery, offering greater precision and minimally invasive techniques. The innovative approach is expected to reduce patient recovery time and surgical risks, potentially transforming how lung transplants are conducted in the future and setting a new standard in thoracic surgery.
• In September 2023, United Therapeutics Corporation announced the successful xenotransplantation of a UHeart xenoheart into a living patient and initiated a study on the UThymoKidney xenokidney. This innovative program aims to tackle the critical shortage of transplantable organs for individuals suffering from end-stage chronic diseases, offering hope through advanced biotechnology and paving the way for future developments in xenotransplantation.
• In February 2022, Amnio Technology introduced two new membrane products: the PalinGen Dual-Layer Membrane and the Dual Layer PalinGen X-Membrane. These novel allografts, like the entire PalinGen membrane product line, undergo minimal manipulation, are intended for homologous use, and are chorion-free.
• In February 2022, Orthofix Medical unveiled Opus BA, a synthetic bioactive bone graft solution designed for cervical and lumbar spine fusion procedures. Opus BA can effectively fill bone voids or gaps within the skeletal system.
• In September 2021, Kidney Transplant Collaborative (KTC) was established as a national nonprofit organization headquartered in Washington, DC. KTC is dedicated to enhancing kidney transplants while addressing financial barriers and other challenges faced by recipients and donors throughout the transplant process.

Key Market Players

• Abbvie, Inc.
• Arthrex, Inc.
• Zimmer Biomet
• Medtronic plc
• Novartis AG
• Stryker Corporation
• 21st Century Medicine
• BiolifeSolutions, Inc.
• Teva Pharmaceuticals Industries Ltd.
• Veloxis Pharmaceutical Inc.

Report Scope:

In this report, the Global Organ Transplant Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

            ·         Organ Transplant Market, By Product:

o   Tissue Products

o   Organ Preservation Products

o   Transplant Diagnostics

o   Immunosuppressant Drugs

o   Others

•          Organ Transplant Market, By Application:

o   Organ Transplantation

o   Tissue Transplantation

            ·         Organ Transplant Market, By Type of Transplant:

o   Autograft

o   Allograft

o   Others

            ·         Organ Transplant Market, By End User:

o   Hospitals

o   Transplant Centers

o   Others

            ·         Organ Transplant Market, By Region:

o   North America

§  United States

§  Canada

§  Mexico

o   Europe

§  France

§  United Kingdom

§  Italy

§  Germany

§  Spain

o   Asia-Pacific

§  China

§  India

§  Japan

§  Australia

§  South Korea

o   South America

§  Brazil

§  Argentina

§  Colombia

o   Middle East & Africa

§  South Africa

§  Saudi Arabia

§  UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Organ Transplant Market.

Available Customizations:

Global Organ Transplant market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

• Detailed analysis and profiling of additional market players (up to five).

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