Nicotinamide Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Sales Channel (Direct, Indirect), By End Use (Pharmaceuticals, Cosmetics & Personal Care, Food & Beverages, Animal Feed, Chemicals), By Region and Competition, 2021-2031F

Forecast Period	2027-2031
Market Size (2025)	USD 717.21 Million
CAGR (2026-2031)	6.78%
Fastest Growing Segment	Pharmaceuticals
Largest Market	Asia Pacific
Market Size (2031)	USD 1063.13 Million

Market Overview

The Global Nicotinamide Market will grow from USD 717.21 Million in 2025 to USD 1063.13 Million by 2031 at a 6.78% CAGR. Nicotinamide is the amide form of Vitamin B3 and serves as a critical water soluble nutrient utilized extensively in pharmaceutical formulations, cosmetic applications, and animal nutrition. The market is fundamentally driven by the escalating prevalence of dermatological conditions which necessitates effective skin barrier treatments and the robust expansion of the global livestock sector requiring high performance feed additives for disease prevention. Additionally, a growing consumer focus on preventative healthcare significantly increases the industrial consumption of vitamin based dietary supplements.

However, the market confronts a substantial challenge regarding supply chain volatility and the geographic concentration of manufacturing. This heavy reliance on specific regions for raw material synthesis creates vulnerability to trade fluctuations and logistical bottlenecks which can impede consistent procurement. According to the European Feed Manufacturers' Federation, in 2025, the European Union depended on imports for more than 75% of its Vitamin B3 supply. This statistic underscores the significant risk associated with centralized global production hubs and the potential for disruption in downstream industries.

Key Market Drivers

The surging demand for cosmeceuticals and anti-aging skincare formulations is fundamentally reshaping the Global Nicotinamide Market, as the compound is increasingly valued for its ability to enhance skin barrier function and reduce hyperpigmentation. Cosmetic manufacturers are aggressively incorporating high-purity Vitamin B3 into serums and creams to cater to an educated consumer base seeking multifunctional active ingredients. This trend is quantified by high consumer interest; according to Foundation, November 2025, in the 'New data reveals top skincare ingredients of 2024' report, Niacinamide ranked as the fourth most searched skincare ingredient, underscoring its pivotal role in modern beauty regimens alongside established actives like retinol. This sustained popularity is compelling chemical suppliers to expand production capacities for cosmetic-grade nicotinamide to meet the specific purity requirements of the personal care sector.

Simultaneously, the market is propelled by the expansion of the animal feed industry driven by global livestock production, where nicotinamide remains an essential additive for metabolic health and disease prevention in poultry and swine. As meat consumption rises globally, the industrial requirement for feed-grade vitamins intensifies to ensure optimal herd performance and food security. According to Alltech, November 2025, in the '2025 Agri-Food Outlook', global feed production grew by 1.2% in 2024, reaching a total volume of 1.396 billion metric tons. This increase in feed tonnage directly correlates with higher procurement of Vitamin B3. Reflecting this sectoral strength, according to dsm-firmenich, February 2025, their Animal Nutrition & Health business unit delivered an organic sales growth of 5% in 2024, highlighting the robust commercial momentum within the livestock nutrition ecosystem.

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Key Market Challenges

The Global Nicotinamide Market faces a significant impediment to growth due to the intense geographic concentration of manufacturing capabilities. This heavy reliance on a limited number of regional production hubs creates a fragile supply chain architecture where singular localized events, such as regulatory shifts or logistical failures, can trigger widespread availability issues. Consequently, downstream industries are frequently exposed to severe price volatility and inconsistent raw material flow, which hampers their ability to execute long-term expansion strategies and undermines the stability required for consistent market development.

The extent of this structural vulnerability is evidenced by recent trade data that quantifies the market's dependence on specific export origins. According to the China Chamber of Commerce for Import & Export of Medicines & Health Products, in 2024, China's total vitamin exports were valued at approximately USD 3.45 billion, with the United States market absorbing USD 840 million of this volume. This statistic illustrates the critical bottleneck where global supply security is tethered to the operational output of one country, creating a risk profile that deters investment and creates friction in the global distribution network.

Key Market Trends

Manufacturers are increasingly transitioning from traditional chemical synthesis to green biomanufacturing processes, utilizing chemo-enzymatic and microbial fermentation methods to lower environmental impact and ensure regulatory compliance. This shift is fundamentally different from general supply chain adjustments, as it focuses on minimizing the carbon footprint of production to appeal to sustainability-conscious stakeholders. Major industry players are formalizing these commitments through rigorous validation frameworks to ensure their manufacturing advancements meet global climate standards. According to Lonza, April 2025, in the 'Sustainability Report 2024', the company had its near-term greenhouse gas reduction targets validated by the Science Based Targets Initiative in 2024, committing to reduce absolute Scope 1 and 2 emissions by 42% by 2030, a move that sets a new benchmark for eco-efficient nicotinamide production.

Simultaneously, the market is witnessing a distinct expansion into the male grooming sector, driven by a demographic shift where men are actively seeking functional skincare ingredients like Nicotinamide for its non-greasy, barrier-strengthening properties. Unlike the broad cosmeceutical demand characterized by general anti-aging formulations, this trend is specific to male consumers utilizing digital platforms to educate themselves on ingredient efficacy and product selection. This growing engagement is evident in social media search behaviors that quantify specific ingredient interest. According to Cosmetics Business, July 2025, in the 'Men's Trends Report', searches for niacinamide serum among male users on Pinterest increased by 35%, highlighting the ingredient's rising status as a staple in men's personal care routines.

Segmental Insights

The pharmaceuticals segment represents the fastest-growing category within the global nicotinamide market, driven by the increasing application of vitamin B3 in therapeutic treatments. This expansion is primarily fueled by the rising prevalence of dermatological disorders and severe vitamin deficiencies, specifically pellagra, which necessitates clinical-grade supplementation. Furthermore, ongoing research into the efficacy of nicotinamide for managing diabetes and oncological conditions is broadening its medicinal scope. Continued validation from regulatory entities, such as the United States Food and Drug Administration, regarding therapeutic usage supports its safety profile and accelerates adoption across the healthcare sector.

Regional Insights

Asia Pacific holds a dominant position in the Global Nicotinamide Market, driven by its dual role as a major manufacturing hub and a rapidly expanding consumption center. The region benefits from extensive production facilities in China and India, which provide a cost-effective supply of raw materials for global distribution. Market growth is further propelled by the robust personal care industry, particularly in South Korea and Japan, where nicotinamide is a staple ingredient in functional skincare formulations. Additionally, adherence to quality standards enforced by agencies like China’s National Medical Products Administration ensures product safety, reinforcing the region's industrial leadership.

Recent Developments

• In November 2025, Niagen Bioscience, Inc. (formerly ChromaDex Corp.) announced the results of a groundbreaking randomized controlled clinical trial evaluating the impact of its patented Nicotinamide Riboside (NR) ingredient, Niagen, on patients with Long COVID. The study, published in eClinicalMedicine, revealed that daily supplementation with this form of Vitamin B3 significantly increased NAD+ levels and led to improvements in executive functioning, fatigue, depression, and sleep quality compared to baseline assessments. This breakthrough research underscored the potential of NAD+ precursors in addressing complex post-viral conditions and expanded the therapeutic research landscape for Vitamin B3 derivatives beyond traditional nutritional applications.
• In March 2025, dsm-firmenich released the findings of a new in vivo study highlighting the efficacy of its Niacinamide PC ingredient in addressing skin concerns associated with menopause. The research demonstrated that the ingredient significantly improved the resilience and health of post-menopausal skin by strengthening the skin barrier and protecting against collagen degradation. Specifically, the study reported a 27% reduction in collagen degradation markers and a 30% increase in ceramide levels within one month of treatment. The company positioned this science-backed application of Vitamin B3 as a key solution for formulations targeting the specific needs of women during the menopausal transition, supporting skin structure and hydration.
• In January 2025, Jubilant Ingrevia Limited commissioned a new cGMP-compliant manufacturing facility in Bharuch, Gujarat, specifically designed to produce Niacinamide for the global market. The new plant, with a capacity of 5,000 metric tonnes, was established to manufacture nutraceutical and dietary-active ingredients for human consumption, expanding upon the company's existing USFDA-approved infrastructure. This strategic expansion aimed to cater to major international customers in the food, nutrition, and cosmetics sectors, and facilitated the company's entry into the global infant nutrition market with food-grade Niacin. The facility was also positioned to produce high-value, high-margin grades of Vitamin B3, thereby reducing the company's exposure to volatility in the feed-grade segment.
• In December 2024, Lonza announced a major strategic shift affecting its position in the nutrition ingredients sector, including the market for Vitamin B3. During its Investor Update, the company outlined its "One Lonza" strategy, which involved a decision to exit its Capsules & Health Ingredients (CHI) business to focus exclusively on its Contract Development and Manufacturing Organization (CDMO) operations. This divestment plan signaled a significant restructuring for the company, which has historically been a leading global producer of Niacinamide. The move was designed to streamline the organization's focus on high-growth biologic and technological modalities while separating its specialty ingredients portfolio.

Key Market Players

• Nebula Health Care
• Suchem Laboratory
• Western Drugs Limited
• Roopa industries limited
• S.V. Labs Pvt. Ltd.
• Veer Chemie & Aromatics pvt ltd.
• Optimus Drugs Pvt. Ltd
• NIGAM FINECHEM PVT. LTD
• Ishita Drugs & Industries Ltd
• Anhui Redpont Biotechnology Co., Ltd

By Sales Channel	By End Use	By Region
Direct Indirect	Pharmaceuticals Cosmetics & Personal Care Food & Beverages Animal Feed Chemicals	North America Europe Asia Pacific South America Middle East & Africa

Report Scope:

In this report, the Global Nicotinamide Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Nicotinamide Market, By Sales Channel:

• Direct
• Indirect

• Nicotinamide Market, By End Use:

• Pharmaceuticals
• Cosmetics & Personal Care
• Food & Beverages
• Animal Feed
• Chemicals

• Nicotinamide Market, By Region:

• North America
• United States
• Canada
• Mexico
• Europe
• France
• United Kingdom
• Italy
• Germany
• Spain
• Asia Pacific
• China
• India
• Japan
• Australia
• South Korea
• South America
• Brazil
• Argentina
• Colombia
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE