Extracorporeal Membrane Oxygenation Machine Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Component Type (Pumps, Oxygenator, Controllers, Cannula, Accessories), By Modality (Veno-Arterial, Veno-Venous, Arterio-Venous), By Patient Type (Neonates, Pediatric, Adult), By Application (Respiratory, Cardiac, ECPR), By Region and Competition, 2021-2031F

Forecast Period	2027-2031
Market Size (2025)	USD 441.63 Million
CAGR (2026-2031)	5.15%
Fastest Growing Segment	Pumps
Largest Market	North America
Market Size (2031)	USD 596.92 Million

Market Overview

The Global Extracorporeal Membrane Oxygenation Machine Market will grow from USD 441.63 Million in 2025 to USD 596.92 Million by 2031 at a 5.15% CAGR. An Extracorporeal Membrane Oxygenation (ECMO) machine is a specialized life-support device that provides prolonged cardiac and respiratory assistance to patients whose heart and lungs are unable to function adequately. The growth of this market is primarily supported by the rising global prevalence of severe cardiovascular and respiratory diseases, such as acute respiratory distress syndrome, alongside an aging population that increasingly requires advanced critical care interventions. According to the Extracorporeal Life Support Organization, in 2024, it was reported that the registry had cumulatively enrolled over 200,000 patients, underscoring the expanding utilization of this therapy for life-threatening conditions.

Despite the strong demand, the market faces a significant challenge regarding the high costs and clinical risks associated with ECMO procedures, such as bleeding and infection. These factors, combined with the necessity for highly specialized training and infrastructure, create substantial barriers to adoption, particularly in healthcare settings with limited financial resources or technical expertise.

Key Market Drivers

The rising prevalence of cardiovascular and respiratory diseases serves as the primary catalyst for the expansion of the Global Extracorporeal Membrane Oxygenation Machine Market. As the incidence of conditions such as heart failure and acute respiratory distress syndrome intensifies, the clinical necessity for mechanical circulatory support systems becomes increasingly critical. This burden is substantial; according to the American Heart Association, January 2024, in the 'Heart Disease and Stroke Statistics—2024 Update', nearly half of all adults in the United States, approximately 48.6%, have some form of cardiovascular disease. Consequently, healthcare providers are compelled to integrate advanced life-support technologies to manage this growing patient population, directly fueling the demand for ECMO interventions as a bridge to recovery or transplantation.

Simultaneously, the market is being propelled by the rising adoption of extracorporeal cardiopulmonary resuscitation and the expansion of specialized critical care infrastructure. This trend is evident in the financial performance of major industry players, reflecting a broader surge in device utilization. For instance, according to LivaNova, May 2024, in the 'First Quarter 2024 Results', revenue for the Cardiopulmonary segment increased by 14.8% compared to the previous year, highlighting the accelerated uptake of these therapies. This growth is further substantiated by the scale of operations within the broader sector; according to Terumo Corporation, May 2024, in the 'Consolidated Financial Results for the Fiscal Year Ended March 31, 2024', the company reported a total revenue increase of 12.4% year-on-year, underscoring the significant commercial magnitude and sustained investment in these critical care technologies.

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Key Market Challenges

The high costs and substantial clinical risks associated with Extracorporeal Membrane Oxygenation procedures constitute a significant restraint on the growth of the global market. Hospitals face considerable financial burdens not only from the initial capital expenditure for these complex machines but also from the ongoing expenses related to specialized infrastructure and the requirement for highly trained multidisciplinary teams. These economic barriers prevent smaller or resource-limited healthcare facilities from adopting the technology, thereby restricting the market's total addressable customer base to major medical centers.

Furthermore, the prevalence of severe complications limits the therapy's application to a last-resort intervention rather than a standard treatment protocol. This clinical volatility is evidenced by recent industry data highlighting the difficulty of achieving positive outcomes in high-risk groups. According to the Extracorporeal Life Support Organization's Registry International Report published in 2024, the survival rate to hospital discharge for adult patients receiving extracorporeal cardiopulmonary resuscitation was recorded at only 29.5 percent. Such low survival figures reinforce the perception of the procedure as a high-risk gamble, causing clinicians to exercise extreme caution in patient selection and ultimately hampering the volume of procedures performed globally.

Key Market Trends

The emergence of compact and lightweight transportable ECMO systems is fundamentally reshaping the market by decoupling advanced life support from static, tertiary care settings. These miniaturized devices facilitate the safe inter-hospital transfer of critically ill patients, effectively operationalizing the "hub-and-spoke" care model where smaller facilities can stabilize patients before transport to specialized centers. This shift towards mobility addresses the logistical bottlenecks of traditional, cumbersome consoles, thereby expanding the technology's geographical reach and application in field settings. According to the American College of Surgeons, September 2025, in the 'ECMO Expands from Rare Rescue to Real Option' article, a survey of US programs estimated that 63 out of 274 adult ECMO centers now offer mobile ECMO services, highlighting the rapid infrastructural investment in transport capabilities to improve patient access.

Simultaneously, the integration of artificial intelligence for real-time predictive analytics is revolutionizing patient management by enhancing clinical decision-making accuracy. Manufacturers are increasingly embedding machine learning algorithms into ECMO consoles to analyze complex physiological data streams, enabling early detection of complications such as clot formation or oxygenator failure before they become critical. This technological leap moves the therapy from a reactive maintenance model to a proactive precision medicine approach, directly mitigating the high mortality risks associated with the procedure. Highlighting this potential, according to Integration Health, April 2025, in the 'AI and ECMO: The Future of Mortality Prediction in Critical Care' report, a newly validated AI-driven model demonstrated over 93% predictive accuracy for 28-day mortality risk in Veno-Arterial ECMO patients, offering clinicians a powerful new tool for optimizing patient selection and care planning.

Segmental Insights

The Pumps segment identifies as the fastest-growing category in the Global Extracorporeal Membrane Oxygenation Machine Market due to substantial improvements in centrifugal pump mechanics. These devices now utilize technologies such as magnetic levitation to prevent friction, which notably decreases blood damage and clotting during long-term use. This technological progression addresses critical safety concerns in treating acute respiratory and cardiac failure. Furthermore, continuous product authorizations by regulatory entities such as the US Food and Drug Administration have encouraged healthcare institutions to upgrade their equipment, thereby fueling the accelerated demand for these essential system components globally.

Regional Insights

North America holds a dominant position in the global Extracorporeal Membrane Oxygenation machine market, primarily driven by the rising incidence of severe cardiopulmonary conditions requiring critical care. The region benefits from a well-established healthcare infrastructure and significant expenditure on advanced medical technologies. Market growth is further sustained by favorable regulatory frameworks, including streamlined product approvals from the U.S. Food and Drug Administration, which encourages innovation and accessibility. Additionally, the widespread availability of specialized training programs and supportive reimbursement policies for life support procedures continues to drive device adoption across the region.

Recent Developments

• In March 2025, Terumo Corporation initiated the commercial release of the Capiox Centrifugal Pump Controller SP-300, a sophisticated drive unit integral to its extracorporeal circulation systems. This new device was developed to serve as a core component for extracorporeal membrane oxygenation setups, which are vital for providing emergency support to patients with severe respiratory or cardiac, conditions. The launch introduced advanced data monitoring capabilities and improved interoperability with the company's existing blood circuit kits, aiming to simplify complex procedures for clinical teams. This product evolution reflects the company's ongoing commitment to delivering durable and precise technologies that support long-term care in intensive care units globally.
• In February 2025, Getinge announced a strategic restructuring plan to discontinue its cardiopulmonary surgical perfusion product line, allowing the company to redirect capital and resources toward its growing Extracorporeal Life Support business. This major operational shift was designed to strengthen the company's position in the extracorporeal membrane oxygenation market, a sector identified for its high growth potential and strategic importance. By phasing out legacy hardware such as heart-lung machines, the organization intends to accelerate innovation and production within its ECMO and transplant portfolios. Management emphasized that this focused investment strategy would enhance the development of next-generation therapies for treating acute cardiac and pulmonary failure.
• In November 2024, Fresenius Medical Care entered into a significant group purchasing agreement with Premier, Inc. for its Novalung System, a key technology in the extracorporeal membrane oxygenation market. This strategic collaboration grants the company access to a vast network of member hospitals and health systems across the United States, allowing for streamlined procurement of its heart and lung support therapies. The agreement is intended to accelerate the commercial adoption of the console, which provides long-term respiratory and cardiopulmonary support for critically ill patients. By securing this partnership, the manufacturer aims to expand its footprint in the intensive care sector and ensure broader availability of its life-saving mechanical circulatory support solutions.
• In September 2024, Inspira Technologies formally launched its INSPIRA ART100 system at the Annual Extracorporeal Life Support Organization Conference, a premier event for the global critical care community. The newly introduced system, which had previously received regulatory clearance for cardiopulmonary bypass and certification for extracorporeal membrane oxygenation in specific regions, was showcased to highlight its potential in advanced life support. This launch represented a significant milestone in the company's strategy to deploy its augmented respiration technology, designed to function as a highly efficient extracorporeal perfusion circuit. The event allowed the company to demonstrate the device's capabilities in stabilizing patient oxygen levels to industry experts and potential hospital partners.

Key Market Players

• India Medtronic Private Limited
• Terumo Cardiovascular Systems Corporation
• MAQUET Holding B.V. & Co. KG
• Medos Medizintechnik AG
• Nipro Medical Corporation
• MicroPort Scientific Corporation
• XENIOS AG
• LivaNova PLC
• EUROSETS S.r.l.

By Component Type	By Modality	By Patient Type	By Application	By Region
Pumps Oxygenator Controllers Cannula Accessories	Veno-Arterial Veno-Venous Arterio-Venous	Neonates Pediatric Adult	Respiratory Cardiac ECPR	North America Europe Asia Pacific South America Middle East & Africa

Report Scope:

In this report, the Global Extracorporeal Membrane Oxygenation Machine Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Extracorporeal Membrane Oxygenation Machine Market, By Component Type:

• Pumps
• Oxygenator
• Controllers
• Cannula
• Accessories

• Extracorporeal Membrane Oxygenation Machine Market, By Modality:

• Veno-Arterial
• Veno-Venous
• Arterio-Venous

• Extracorporeal Membrane Oxygenation Machine Market, By Patient Type:

• Neonates
• Pediatric
• Adult

• Extracorporeal Membrane Oxygenation Machine Market, By Application:

• Respiratory
• Cardiac
• ECPR

• Extracorporeal Membrane Oxygenation Machine Market, By Region:

• North America
• United States
• Canada
• Mexico
• Europe
• France
• United Kingdom
• Italy
• Germany
• Spain
• Asia Pacific
• China
• India
• Japan
• Australia
• South Korea
• South America
• Brazil
• Argentina
• Colombia
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE