Dermatology Excimer Laser Market – Global Industry Size, Share, Trends, Opportunity & Forecast, Segmented by Product (Tabletop Excimer Lasers, Hand-held Excimer Lasers, Trolley Mounted Excimer Lasers), By Application (Psoriasis, Vitiligo, Atopic Dermatitis, Allergic Rhinitis, Alopecia Areata, Others), End User (Hospitals, Dermatology Clinics, Plastic Surgery Centers), By Region & Competition, 2021-2031F

Forecast Period	2027-2031
Market Size (2025)	USD 0.65 Billion
CAGR (2026-2031)	9.98%
Fastest Growing Segment	Trolley Mounted Excimer Lasers
Largest Market	North America
Market Size (2031)	USD 1.15 Billion

Market Overview

The Global Dermatology Excimer Laser Market will grow from USD 0.65 Billion in 2025 to USD 1.15 Billion by 2031 at a 9.98% CAGR. Dermatology excimer lasers are specialized medical devices that utilize noble gas mixtures to emit a concentrated beam of ultraviolet B radiation at a specific wavelength of 308 nanometers to treat autoimmune skin conditions such as psoriasis and vitiligo. The primary drivers supporting market growth include the rising global incidence of these chronic dermatological disorders and a growing preference for targeted phototherapy that minimizes exposure to healthy surrounding tissue. According to the National Psoriasis Foundation, in 2024, an estimated 7.5 million adults in the United States were reported to be affected by psoriasis, a figure that underscores the substantial patient pool necessitating effective long-term management solutions like targeted laser therapy.

Despite these strong growth factors, the market faces a significant impediment due to the intense competition from rapidly advancing systemic pharmaceutical therapies. The increasing availability and adoption of high-efficacy biologic drugs and Janus kinase inhibitors offer patients convenient oral or injectable alternatives that address systemic inflammation rather than just localized symptoms. This shift toward pharmaceutical interventions effectively diverts a portion of the eligible patient population away from phototherapy treatments, potentially limiting the adoption rates of excimer laser hardware in dermatology clinics particularly for cases involving extensive body surface area coverage.

Key Market Drivers

The rising global prevalence of psoriasis and vitiligo serves as a primary catalyst for the expansion of the dermatology excimer laser market, directly expanding the pool of patients seeking targeted phototherapy. As autoimmune skin conditions become more widespread, the demand for non-systemic treatments that can effectively manage localized plaques and depigmentation increases. This growing patient burden is not merely clinical but has significant economic implications that drive the search for efficient management solutions. According to the National Psoriasis Foundation, in 2024, individuals with psoriasis miss an average of 7.71 nonrecreational workdays annually, a statistic that highlights the productivity loss necessitating effective interventions like excimer laser therapy. Furthermore, the market opportunity is bolstered by updated epidemiological data regarding pigmentary disorders. According to HCPLive, August 2024, in the 'Study Highlights Global Prevalence of Vitiligo, Regional Trends', a systematic review determined the global prevalence of vitiligo to be 0.40%, with West Asia exhibiting a notably higher regional prevalence rate of 0.77%.

Simultaneously, the increasing adoption of targeted phototherapy modalities and the expansion of specialized hardware in clinics are solidifying the market's trajectory. Medical device manufacturers are aggressively expanding their installed base to ensure these advanced systems are accessible in dermatology practices, thereby facilitating higher procedure volumes. This expanded accessibility allows clinicians to offer precise 308 nm UVB treatments as a viable alternative to pharmaceuticals for eligible patients. Evidence of this growing clinical footprint is reflected in corporate operational data. According to STRATA Skin Sciences, March 2024, in the 'Fourth Quarter and Full Year 2023 Financial Results', the company reported a domestic installed base of 923 XTRAC devices, demonstrating the sustained integration of excimer laser technology into the healthcare infrastructure despite competitive pressures.

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Key Market Challenges

The Global Dermatology Excimer Laser Market faces a substantial impediment arising from the intense competition posed by rapidly advancing systemic pharmaceutical therapies. While excimer lasers offer effective localized treatment, the increasing availability of high-efficacy biologics and Janus kinase inhibitors provides patients with systemic relief that targets the root cause of inflammation rather than merely addressing surface symptoms. This distinction is particularly critical for patients with comorbidities or extensive disease coverage, as systemic drugs offer a more comprehensive management solution compared to the targeted approach of phototherapy. Consequently, the convenience and holistic efficacy of these pharmaceutical alternatives effectively divert a significant portion of the eligible patient population away from laser-based treatments.

This trend directly hampers the adoption rates of excimer laser hardware by shrinking the addressable market for device manufacturers. According to the National Psoriasis Foundation, in 2024, it was reported that up to 33 percent of people with psoriasis develop psoriatic arthritis. This statistic underscores that a large segment of the patient base requires systemic medication to manage joint deterioration, a function excimer lasers cannot perform. As clinical guidelines increasingly favor these pharmaceutical interventions for such cases to ensure comprehensive care, the demand for localized phototherapy equipment in dermatology clinics experiences a corresponding decline.

Key Market Trends

The adoption of combination regimens with topical agents and adjunctive therapies is fundamentally reshaping clinical protocols within the dermatology excimer laser market. Clinicians are increasingly moving away from monotherapy, instead pairing 308 nm excimer laser treatment with biological agents, Janus kinase inhibitors, or regenerative techniques to enhance repigmentation in refractory cases. This synergistic approach addresses the limitations of standalone phototherapy, particularly for resistant anatomical sites, thereby sustaining device utility in a competitive landscape. According to the Journal of Cutaneous and Aesthetic Surgery, October 2024, in the study 'Triple combination of fractional carbon dioxide laser, 308-nm excimer lamp, and platelet-rich plasma in refractory vitiligo', the patient group treated with the combination protocol demonstrated a significantly superior efficacy rate of 56.1 percent compared to 26.8 percent in the control group managed with standard topical regimens.

Simultaneously, the market is experiencing accelerated penetration across the Asia-Pacific region, driven by expanding healthcare infrastructure and rising procedural volumes in key economies such as China and India. Manufacturers are strategically shifting their focus toward these high-growth markets by establishing direct operational footprints and securing local regulatory approvals for their energy-based portfolios. This geographic diversification allows companies to offset saturation in Western regions by capitalizing on the burgeoning demand for advanced dermatological hardware in Asia. According to Sisram Medical Ltd, September 2024, in the 'Interim Report 2024', the company's revenue derived from the Asia-Pacific region increased by 15.5 percent year-over-year to reach US$56.0 million, a growth trajectory attributed largely to the robust performance of its energy-based device segment in the Chinese market.

Segmental Insights

The Trolley Mounted Excimer Lasers segment represents the fastest growing category in the Global Dermatology Excimer Laser Market, driven by the operational requirements of modern medical facilities. Healthcare providers increasingly prioritize these units because they combine high power output with the flexibility to move equipment between treatment rooms, thereby optimizing patient workflow and facility utilization. This mobility allows hospitals and specialized clinics to manage higher patient volumes efficiently while treating chronic skin conditions like psoriasis and vitiligo. Consequently, the balance of stability and portability positions these systems as the preferred choice for institutions seeking durable and practical phototherapy solutions.

Regional Insights

North America maintains a leading position in the global dermatology excimer laser market, driven by the rising prevalence of autoimmune skin conditions such as psoriasis and vitiligo. The region benefits from an established healthcare infrastructure and favorable reimbursement policies that support patient access to targeted phototherapy. Additionally, the U.S. Food and Drug Administration facilitates market growth through the consistent approval of safe medical devices. This regulatory support, combined with increasing clinical adoption by dermatologists, ensures that North America remains the primary hub for these therapeutic solutions.

Recent Developments

• In October 2025, STRATA Skin Sciences announced the publication of a groundbreaking clinical case study in Case Reports in Oncology, documenting the successful use of its 308nm excimer laser to treat a rare form of cutaneous T-cell lymphoma known as poikilodermatous mycosis fungoides. The study, conducted by researchers at Tohoku University, reported that the patient experienced near-complete resolution of lesions after a limited number of treatment sessions. This research represented a significant milestone as the first English-language report validating the safety and efficacy of excimer laser therapy for this specific and difficult-to-treat dermatological condition.
• In September 2025, STRATA Skin Sciences highlighted the results of a peer-reviewed randomized controlled trial published in the International Journal of Dermatology, which detailed the efficacy of its 308nm excimer laser in combination with an oral Janus kinase (JAK) inhibitor. The study demonstrated that the combination therapy provided superior repigmentation rates and a faster response for vitiligo patients compared to monotherapy or conventional treatments. The company noted that these findings supported its ongoing efforts to expand reimbursement coverage for vitiligo treatments and further validated the device's role in personalized medicine approaches for autoimmune skin diseases.
• In October 2024, STRATA Skin Sciences reported that its longstanding strategic partner in Japan, JMEC Co., Ltd., sponsored a seminar at the 75th Annual Meeting of the Chubu Branch of the Japanese Dermatological Association. The event featured lectures by prominent dermatologists who presented clinical data on the successful treatment of vitiligo and alopecia areata using the company’s excimer laser technology. This collaboration underscored the continued adoption and clinical validation of the device in the Japanese market, where the company has placed over 100 units since launching the product in the region.
• In April 2024, STRATA Skin Sciences announced the renewal of exclusive distribution agreements with its partners in China and Japan, solidifying its presence in the dermatology excimer laser market in Asia. These three-year agreements involved minimum unit placements and purchase requirements for the company’s XTRAC and VTRAC devices, which are widely used for treating psoriasis, vitiligo, and other skin conditions. The President and CEO of the company highlighted that these renewals, alongside a similar agreement in South Korea, would improve visibility for the international business segment, which accounted for nearly a third of total revenue in the previous year.

Key Market Players

• Lumenis
• Hologic
• Sciton
• Asclepion Laser Technologies
• Eagle Photonics
• ConBio
• Reliant Technologies
• Fotona
• Cutera
• Eveo

By Application	By Region
Psoriasis Vitiligo Atopic Dermatitis Allergic Rhinitis Alopecia Areata Others	North America Europe Asia Pacific South America Middle East & Africa

Report Scope:

In this report, the Global Dermatology Excimer Laser Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Dermatology Excimer Laser Market, By Application:

• Psoriasis
• Vitiligo
• Atopic Dermatitis
• Allergic Rhinitis
• Alopecia Areata
• Others

• Dermatology Excimer Laser Market, By Region:

• North America
• United States
• Canada
• Mexico
• Europe
• France
• United Kingdom
• Italy
• Germany
• Spain
• Asia Pacific
• China
• India
• Japan
• Australia
• South Korea
• South America
• Brazil
• Argentina
• Colombia
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE