Report Description

Forecast Period


Market Size (2022)

USD 4.20 billion

CAGR (2023-2028)


Fastest Growing Segment

Methyl Chloride

Largest Market

Asia Pacific

Market Overview

Global Chloromethane Market has valued at USD 4.20 billion in 2022 and is anticipated to project robust growth in the forecast period with a CAGR of 3.33% through 2028. Chloromethane is derived from methane and is an extremely flammable, toxic, and colorless gas with a faint sweet smell. Its production involves a chemical reaction between hydrogen chloride and methanol, and it is typically transported as a liquid under its vapor pressure. While it was previously utilized as a refrigerant, its use was discontinued due to its toxicity and flammability. Nowadays, chloromethane finds its main application in the production of active pharmaceutical ingredients and the silicone industry, along with other chemical uses. Although naturally occurring, chloromethane can also be prepared synthetically. The formation of chloromethane occurs through the action of sunlight on biomass and chlorine found in oceanic systems. Due to its poisonous nature, chloromethane is unsuitable for personal use. It encompasses various compounds such as methyl chloride, methylene chloride, carbon tetrachloride, and chloroform. The rising demand from the chemical industries is expected to drive the growth of the chloromethane market. Manufacturers are focusing on strategies to balance supply and demand, explore new applications in vertical industries, and comply with regulations across different regions. Chloromethane is used as a refrigerant, although its high toxicity levels restrict its use in consumer products. Currently, it serves as a chemical intermediate in the production of derivatives like methyl chloride, methylene chloride, carbon tetrachloride, and chloroform. It is also utilized in the production of silicone polymers and butyl rubber. Methylene chloride finds applications in metal cleaning within the pharmaceutical industry. Chloroform is used in agricultural products, pharmaceuticals, and as a chemical intermediate. Methyl chloride is employed in the manufacturing of hydro-fluoro olefins, which serve as replacements for hydrofluorocarbons. The increasing adoption of hydrofluorocarbon alternatives is expected to drive the demand for chloromethanes. However, the high toxicity levels and environmental concerns associated with chloromethane usage may hinder market growth. Substitutes like chlorofluorocarbons, hydrofluorocarbons, and natural refrigerants are expected to gain preference due to their lower environmental impact. The growth of the chloromethane market is further driven by its use in the drug manufacturing and medical industries, as well as the expanding application of silicones in the electronics and automobile industries. Additionally, the growth in per capita income, improving living standards, and increased healthcare expenditure in Asia-Pacific and other regions have contributed to the demand for products containing chloromethane. The growth of the chloromethane market can be attributed to increasing international trade, technological advancements, the need for refrigerated transport and storage of fresh food products, government support for cold chain infrastructure, and the rising demand for perishable foods. Methyl chloride, used in the production of hydro-fluoro olefins as a replacement for hydrofluorocarbons, plays a significant role in these trends.

 Key Market Drivers

Growing Demand of Chloromethane in Pharmaceutical Industry

The global pharmaceutical industry has undergone remarkable transformations in recent years, driven by technological advancements and innovative research. These advancements have paved the way for new treatment options and drug formulations. Within the pharmaceutical sector, chloromethane has gained significant attention. Also known as methyl chloride (CH3Cl), chloromethane is an essential chemical compound with diverse applications in various industries, including pharmaceuticals. The prevalence of chronic diseases such as diabetes, cardiovascular diseases, and cancer has surged globally, leading to an increased demand for drugs that rely on chloromethane. Chloromethane plays a crucial role in synthesizing anesthetic and analgesic drugs, which are vital for pain management during surgical procedures and medical treatments. Additionally, it is utilized in the synthesis of certain classes of antibiotics, contributing to the development of novel treatments against bacterial infections. Furthermore, chloromethane is involved in the production of cardiovascular medications that help manage heart-related conditions, including hypertension and arrhythmias. It is also utilized in the creation of antidepressant and anti-anxiety medications, which are essential for mental health treatment. Additionally, the compound is used in the synthesis of anti-inflammatory drugs that alleviate pain and inflammation caused by various medical conditions. As the pharmaceutical sector continues to evolve, collaboration between chemical manufacturers, pharmaceutical companies, and regulatory bodies will play a pivotal role in ensuring a sustainable supply of chloromethane while adhering to environmental and safety standards.

Growing Demand of Refrigerants

Traditionally, chlorofluorocarbons (CFCs) and hydrochlorofluorocarbons (HCFCs) were extensively utilized as refrigerants due to their favorable characteristics. However, these substances were found to have significant adverse impacts on the ozone layer and contribute to global warming. Consequently, international agreements like the Montreal Protocol were implemented to phase out their production and consumption. This shift in awareness has stimulated the development and adoption of more environmentally friendly refrigerants, such as hydrofluorocarbons (HFCs) and hydro fluoro olefins (HFOs). While HFCs are less harmful to the ozone layer, they are potent greenhouse gases. On the other hand, HFOs have lower global warming potential (GWP) and are increasingly being embraced as alternatives to HFCs. The chloromethane market is directly influenced by the growing demand for refrigerants, propelled by factors like urbanization, changing lifestyles, and rising global temperatures. As more energy-efficient and environmentally friendly refrigerants gain popularity, the production of chloromethane has become integral to the expansion of the refrigerant industry. Moreover, the emerging trend of circular economy practices is expected to impact the chloromethane market. Prioritizing the recycling and reusing of refrigerants will reduce the demand for raw materials like chloromethane, minimizing the overall environmental impact. As refrigerants with lower GWP values gain prominence, the chloromethane market's role as a vital component of the refrigerant supply chain becomes more significant. Striking a balance between cooling technology demands and sustainable production practices will be crucial in meeting the needs of a rapidly changing world while safeguarding our planet's future.

Download Free Sample Report

Key Market Challenges

Fluctuations in Prices of Raw Materials

Chloromethane is an odorless, flammable gas with a faintly sweet scent. Its primary production involves the reaction of methanol with hydrogen chloride in the presence of a catalyst. Methanol, a crucial feedstock for chloromethane production, is susceptible to price volatility due to various factors. Fluctuations in methanol prices can be attributed to changes in crude oil prices (as methanol is derived from natural gas and oil), geopolitical tensions affecting supply routes, and shifts in demand for other products that also employ methanol as a raw material. For instance, a sudden surge in demand for biofuels, often utilizing methanol as a feedstock, can lead to higher methanol prices. Similarly, disruptions in the supply chain, such as production outages or transportation bottlenecks, can drive methanol prices up. These price fluctuations directly impact the cost structure of chloromethane production. Hydrogen chloride is another critical raw material in chloromethane production. It is commonly obtained as a co-product from processes such as the manufacture of polyvinyl chloride (PVC) and other chemical reactions. However, the availability of hydrogen chloride can be influenced by market demand for these co-products. A decrease in demand for PVC or other hydrogen chloride-derived products can result in reduced availability and potentially higher prices for hydrogen chloride. Furthermore, factors like regulatory changes and environmental concerns regarding the emissions of hydrogen chloride during manufacturing processes can affect its availability and pricing. These factors underline the complexity of the raw material supply chain in the chloromethane market.

Growth in Environmental Concerns

Chloromethane is a volatile organic compound (VOC) and has been classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC). This classification highlights its potential to cause cancer in humans. Moreover, chloromethane has been identified as a significant contributor to ozone depletion when released into the atmosphere. Ozone-depleting substances have been subject to extensive regulation under the Montreal Protocol due to their detrimental impact on the Earth's protective ozone layer, shielding us from harmful ultraviolet (UV) radiation. In response to these environmental concerns, international regulatory bodies have implemented measures to mitigate the adverse effects associated with the production and use of chloromethane. The Montreal Protocol, established in 1987, aims to gradually phase out the production and consumption of ozone-depleting substances, including chloromethane. Consequently, numerous developed and developing nations have implemented stringent regulations and guidelines to reduce chloromethane emissions.

Key Market Trends

Rapid technological advancements

Rapid technological advancements are offering numerous opportunities for the market. These advancements focus on improving production processes, enhancing product quality, and increasing efficiency in chloromethane manufacturing. Technological innovations have led to the development of advanced catalysts and process optimization techniques, resulting in higher yields and improved productivity in chloromethane production. These advancements have increased the supply of chloromethane and reduced production costs, making it more economically viable for various industries. Moreover, advancements in purification and distillation technologies have enhanced the quality of chloromethane, meeting stringent industry and regulatory standards. This has further expanded the application areas of chloromethane, attracting a wider customer base. Furthermore, technological advancements in packaging and storage solutions have improved the safety and transportation of chloromethane, ensuring its availability and accessibility to end-users across different regions.

Segmental Insights

Product Type Insights

In 2022, the Chloromethane market was dominated by the Methyl Chloride and is predicted to continue expanding over the coming years.  Methyl chloride is extensively utilized as a refrigerant and in the production of silicone polymers. The growing refrigeration and construction sectors drive the demand for methyl chloride, as it is employed in the manufacturing of hydrochlorofluorocarbon (HCFC) refrigerants and silicone-based materials.

Application Insights

In 2022, the Chloromethane market was dominated by pharmaceutical segment and is predicted to continue expanding over the coming years. The pharmaceutical industry employs chloromethane as an intermediary for the synthesis of active pharmaceutical ingredients (APIs). The increasing demand for pharmaceuticals, driven by the growing healthcare sector, necessitates the utilization of chloromethane in this segment.

Download Free Sample Report

Regional Insights

The Asia Pacific region has established itself as the leader in the Global Chloromethane Market. Abundant availability of feedstock and significant shale gas reserves in China are expected to drive the manufacturing of the product in the region. These factors have also contributed to a significant growth in chemical production in the region. Additionally, major players are increasingly focusing on high-opportunity markets, such as China and India, due to the easy availability of raw materials and cost-effective skilled labor. One of the key end-use markets for chloromethane in the Asia Pacific region is the pharmaceutical industry. The emergence of new viruses, such as the recent corona threat, has prompted pharmaceutical companies to invest in research and development activities for the development of new drugs. These activities are anticipated to drive the demand for laboratory chemicals and drug additives, including chloromethane.

Recent Developments

  • In January 2023, Nouryon, a global leader in specialty chemicals, announced the acquisition of a Poland-based supplier specializing in chelated micronutrients, foliar, and other specialty agricultural solutions. This strategic move will enable the company to expand its service offerings and enhance its product portfolio for customers in the agricultural industry.
  • In May 2022, AGC Inc., a renowned manufacturer of glass and chemicals worldwide, successfully increased the production capacity of AGC's chlor-alkali business in the Indochina Peninsula. By investing USD 0.76 billion, AGC aims to augment the annual production capacity of caustic soda, polyvinyl chloride (PVC), and vinyl chloride monomer.
  • In April 2019, Nouryon, a prominent entrepreneur, announced the commencement of a construction project at their site in Frankfurt, Germany, scheduled to begin in May. This project aims to increase the capacity for chloromethanes, meeting the growing global customer demand. The expansion is anticipated to be completed by the year 2020.
  • In February 2021, Soliton Inc., a reputable medical device firm renowned for its proprietary and innovative aesthetic platform technology, initiated a new pre-clinical trial in animals.
  • GAIL (India) recently announced the signing of a Memorandum of Understanding (MoU) with Gujarat Alkalies & Chemicals to establish a bioethanol plant in Gujarat with a daily production capacity of 500 liters. This project, estimated at an investment of 1,000 crore rupees, signifies GAIL's commitment to sustainable and renewable energy solutions.

Key Market Players

  • Akzonobel N.V.
  • Shin-Etsu Chemical Co.
  • Gujarat Alkalies and Chemical Limited
  • Ineos Group Ltd.
  • Kem One SASU
  • Solvay SA
  • Occidental Petroleum Corporation
  • Gujarat Fluorochemicals Ltd.
  • SRF Limited
  • Tokuyama Corporation

 By Manufacturing Process

  By Product Type

  By Application

By Region

       Methanol Route

       Methane Route

       Methylene Chloride


       Carbon Tetrachloride

       Methyl Chloride



       Metal Cleaning


       Foam Blowing

       Chemical Intermediaries

       Asia Pacific

       North America


       Middle East & Africa

       South America

Report Scope:

In this report, the Global Chloromethane Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

  •          Chloromethane Market, By Manufacturing Process:

o   Methanol Route

o   Methane Route

  • Chloromethane Market, By Product Type:

o   Methylene Chloride

o   Chloroform

o   Carbon Tetrachloride

o   Methyl Chloride

  • Chloromethane Market, By Application:

o   Pharmaceutical

o   Medical

o   Metal Cleaning

o   Refrigerants

o   Foam Blowing

o   Chemical Intermediaries

  • Chloromethane Market, By Region:

o   Asia Pacific

o   North America

o   Europe

o   Middle East & Africa

o   South America 

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Chloromethane Market.

Available Customizations:

Global Chloromethane Market report with the given market data, Tech Sci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

·         Detailed analysis and profiling of additional market players (up to five).

Global Chloromethane Market is an upcoming report to be released soon. If you wish an early delivery of this report or want to confirm the date of release, please contact us at [email protected]               

Table of content

1.     Product Overview

1.1.   Market Definition

1.2.   Scope of the Market

1.2.1. Markets Covered

1.2.2. Years Considered for Study

1.2.3. Key Market Segmentations

2.     Research Methodology

2.1.   Objective of the Study

2.2.   Baseline Methodology

2.3.   Key Industry Partners

2.4.   Major Association and Secondary Sources

2.5.   Forecasting Methodology

2.6.   Data Triangulation & Validation

2.7.   Assumptions and Limitations

3.     Executive Summary

3.1.   Overview of the Market

3.2.   Overview of Key Market Segmentations

3.3.   Overview of Key Market Players

3.4.   Overview of Key Regions/Countries

3.5.   Overview of Market Drivers, Challenges, Trends

4.     Voice of Customer

5.     Global Chloromethane Market Outlook

5.1.   Market Size & Forecast

5.1.1. By Value

5.2.   Market Share & Forecast

5.2.1. By Manufacturing Process (Methanol Route, Methane Route)

5.2.2. By Product Type (Methylene Chloride, Chloroform, Carbon Tetrachloride, Methyl Chloride)

5.2.3. By Application (Pharmaceutical, Medical, metal Cleaning, Refrigerants, Foam Blowing and Chemical Intermediaries)

5.2.4. By Region

5.2.5. By Company (2022)

5.3.   Market Map