Chloroform Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Grade (Technical Grade, Alcohol Stabilized Grade, Fluorocarbon Grade), By End User (Construction, Agriculture, Transportation, Healthcare, Chemical, Industrial, Others), By Region & Competition, 2021-2031F

Forecast Period	2027-2031
Market Size (2025)	1048.62 Thousand Tonnes
CAGR (2026-2031)	2.77%
Fastest Growing Segment	Technical Grade
Largest Market	Asia Pacific
Market Size (2031)	1235.42 Thousand Tonnes

Market Overview

The Global Chloroform Market will grow from 1048.62 Thousand Tonnes in 2025 to 1235.42 Thousand Tonnes by 2031 at a 2.77% CAGR. Chloroform, chemically identified as trichloromethane, is a dense, colorless, and volatile liquid organic compound primarily utilized as a solvent and a vital precursor in the synthesis of refrigerants and fluoropolymers. The global market is fundamentally driven by the robust industrial demand for fluoropolymers such as polytetrafluoroethylene (PTFE), which are essential for high-performance applications in the automotive and electronics sectors. Furthermore, the sustained requirement for chloroform as a feedstock in the manufacturing of hydrochlorofluorocarbon-22 (HCFC-22), specifically for non-emissive feedstock use, continues to underpin production volumes.

According to Euro Chlor, in 2024, the total chlorine production by its members reached 8,041 kilotonnes, serving as the essential feedstock for the chloromethanes value chain that includes chloroform. Despite this stable upstream supply, the market encounters a significant impediment regarding stringent environmental regulations and health concerns related to the chemical's toxicity and potential carcinogenicity. These regulatory pressures, coupled with the global mandates of the Montreal Protocol to phase out ozone-depleting substances, present a substantial challenge that could constrain future market expansion.

Key Market Drivers

The primary driver propelling the Global Chloroform Market is the surging demand for fluoropolymers, particularly polytetrafluoroethylene (PTFE), which relies heavily on chloroform as a critical feedstock. Chloroform is converted into hydrochlorofluorocarbon-22 (HCFC-22), the essential monomer for producing high-performance fluoropolymers used extensively in the automotive, electronics, and construction industries for their superior chemical resistance and thermal stability. This demand is further amplified by the transition towards lower global warming potential (GWP) refrigerants and specialized blends where chloroform derivatives serve as key intermediates. Evidence of this upward trend is highlighted by The Chemours Company, February 2025, in the 'Fourth Quarter and Full Year 2024 Results', which reported that the Thermal & Specialized Solutions segment achieved a 7% increase in volume during the fourth quarter of 2024, driven significantly by stronger demand for refrigerant blends and performance solutions.

The expansion of the pharmaceutical manufacturing sector also significantly influences market growth, utilizing chloroform as a highly effective solvent for the extraction and purification of antibiotics, alkaloids, and vitamins. As drug production escalates to meet global healthcare needs, particularly in emerging economies like India and China, the consumption of high-purity solvent grades has intensified. According to the India Brand Equity Foundation (IBEF), July 2024, in the 'Indian Pharmaceutical Industry Analysis', the Indian pharmaceutical market registered a robust growth of 8.8% in June 2024, underscoring the rising industrial activity necessitating solvent inputs. This sectoral momentum is mirrored in the broader chlor-alkali value chain; according to Olin Corporation, in 2025, sales in their Chlor Alkali Products and Vinyls segment increased by 9% sequentially in the fourth quarter of 2024, reflecting a recovery in industrial demand for chlorine derivatives including chloroform.

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Key Market Challenges

The primary impediment hampering the Global Chloroform Market is the stringent regulatory framework governing environmental safety and toxicity. The classification of chloroform as a probable carcinogen has necessitated rigid exposure limits, while international mandates under the Montreal Protocol actively target the phase-out of ozone-depleting substances. These regulatory pressures directly constrain the market by enforcing quotas on the production of hydrochlorofluorocarbon-22 (HCFC-22), for which chloroform is a critical feedstock. Consequently, manufacturers face a landscape of shrinking permissible applications and elevated compliance costs, which systematically limits production scalability and deter investment in capacity expansion.

This restrictive operating environment is quantitatively reflected in recent industrial output performance. According to the American Chemistry Council, in 2024, production volumes for basic chemicals in the United States declined by 1.5%. This contraction illustrates the tangible impact of regulatory headwinds on the broader chlor-alkali and intermediates sector. As producers navigate these compounding environmental obligations, the industry witnesses a forced deceleration in output, effectively stalling the growth momentum of the chloroform value chain despite stable upstream material availability.

Key Market Trends

Global production capacities are structurally shifting and consolidating within the Asia-Pacific region, particularly in China and India, establishing these nations as the primary export hubs for technical-grade chloroform. This realignment is driven by the region's robust industrial base and the strategic expansion of local chlor-alkali facilities to meet global demand, effectively replacing legacy capacity in Western regions. A clear indicator of this supply chain transition is the surging operational output in the Indian sector. According to Gujarat Alkalies and Chemicals Limited, August 2024, in the 'Annual Report 2023-24', the company's total production volume across all products, including chlor-alkali derivatives, increased by 12.88% to reach 2,046,173 metric tonnes for the fiscal year. This significant escalation in output validates the trend of Asia-Pacific manufacturers capturing a larger share of the global market.

There is a growing trend toward the use of deuterated chloroform as a premium solvent in Nuclear Magnetic Resonance (NMR) spectroscopy, fueled by intensifying pharmaceutical and academic R&D activities. As structural analysis and quality control of complex organic molecules become paramount in drug discovery, the consumption of high-purity isotopic solvents is expanding. This momentum in laboratory-scale chemical research is quantitatively evidenced by the financial performance of major life science suppliers. According to Merck KGaA, November 2024, in the 'Quarterly Statement Q3 2024', sales in the Life Science business sector increased organically by 2.1% to reach €2,210 million, driven significantly by a recovery in Science & Lab Solutions. This commercial growth underscores the rising essentiality of advanced analytical reagents, including deuterated chloroform, in supporting the global research infrastructure.

Segmental Insights

The Technical Grade segment is currently the fastest growing category in the Global Chloroform Market, primarily driven by its critical role as an industrial feedstock. This grade is essential for synthesizing chlorodifluoromethane, which serves as a vital precursor for the production of fluoropolymers such as Polytetrafluoroethylene (PTFE). Consequently, the expanding automotive and electronics sectors, which rely on these high-performance materials, are fueling demand. Furthermore, while the Montreal Protocol restricts emissive uses of ozone-depleting substances, it permits their production as feedstocks, thereby sustaining the robust consumption of Technical Grade chloroform for fluorocarbon resin manufacturing.

Regional Insights

Asia Pacific commands the Global Chloroform Market, largely driven by the extensive chemical manufacturing capabilities within China and India. The region dominates global consumption due to the high demand for chloroform as a primary feedstock in the production of HCFC-22. While refrigerant usage is evolving, this intermediate remains essential for manufacturing fluoropolymers, specifically Polytetrafluoroethylene (PTFE), which supports the growing automotive and electronics sectors. Additionally, the rapid expansion of the pharmaceutical and agrochemical industries in these economies ensures a consistent requirement for chloroform as a solvent, reinforcing the region's market supremacy.

Recent Developments

• In November 2025, Olin Corporation announced a strategic long-term partnership with Braskem to supply ethylene dichloride and support vinyls production in South America. This collaboration leverages Olin's extensive chlor-alkali production network, which includes major capacities for chlorine and its derivatives such as chloroform and ethylene dichloride. The agreement aligns with Olin's strategy to optimize its global asset utilization and strengthen its structural position in the chlor-vinyls chain, directly influencing the dynamics of the broader chlorinated organics market.
• In December 2024, The Chemours Company entered into a strategic collaboration with the PCC Group to establish a new chlor-alkali production facility in DeLisle, Mississippi. Under this agreement, the PCC Group will construct and operate the plant on Chemours' existing titanium dioxide site, while Chemours secured a long-term supply agreement for chlorine, the primary raw material required for chloroform production. This partnership is designed to enhance supply reliability and operational efficiency for Chemours, ensuring a consistent availability of essential chlor-alkali feedstocks for its downstream chemical value chains.
• In September 2024, Grasim Industries Limited revealed plans to expand its chemical manufacturing operations at Balabadrapuram in the East Godavari district of Andhra Pradesh. The proposed project involves a significant capacity addition for chloromethanes, a group of chemicals that includes chloroform, with a planned increase of 150 tonnes per day (TPD). This development is part of a broader expansion of the company's chlor-alkali capabilities, which also includes increasing caustic soda and chlorine derivative production, thereby reinforcing Grasim's position as a leading player in the domestic and global chloroform market.
• In February 2024, the subsidiary of Gujarat Fluorochemicals Limited (GFL), GFCL EV Products, announced a substantial investment of ₹6,000 crore to expand its production capacity for electric vehicle battery materials over the next four to five years. This strategic initiative aims to cater to high-demand markets in the US, Europe, and India by supplying fluoropolymer-based solutions, including PVDF and PTFE binders, which utilize chloroform as a critical feedstock in their manufacturing value chain. The investment underscores the company's commitment to strengthening its integrated battery chemicals portfolio and capitalization on the global transition to clean energy.

Key Market Players

• Medical Isotopes, Inc.
• MP Biomedicals, LLC
• Oxford Lab Fine Chem LLP
• Alpha Chemika
• Arihant Chemical
• Solvay S.A.
• Tokuyama Corporation
• Shin-Etsu Chemical Co., Ltd.
• Occidental Petroleum Corporation
• Merck KGaA

By Grade	By End User	By Region
Technical Grade Alcohol Stabilized Grade Fluorocarbon Grade	Construction Agriculture Transportation Healthcare Chemical Industrial Others	North America Europe Asia Pacific South America Middle East & Africa

Report Scope:

In this report, the Global Chloroform Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

• Chloroform Market, By Grade:

• Technical Grade
• Alcohol Stabilized Grade
• Fluorocarbon Grade

• Chloroform Market, By End User:

• Construction
• Agriculture
• Transportation
• Healthcare
• Chemical
• Industrial
• Others

• Chloroform Market, By Region:

• North America
• United States
• Canada
• Mexico
• Europe
• France
• United Kingdom
• Italy
• Germany
• Spain
• Asia Pacific
• China
• India
• Japan
• Australia
• South Korea
• South America
• Brazil
• Argentina
• Colombia
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE