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Label-Free Array Systems Market To Be Dominated By The Drug Discovery Segment By 2028

Technological advancement for diagnostics is expected to drive Global Label-Free Array Systems Market in the forecast period, 2024-2028.

According to TechSci Research report, “Label-Free array systems market–Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028, the Global Label-Free Array Systems Market is anticipated to grow at a steady rate in the forecast period, 2024-2028. This can be attributed to the benefits associated with Label-free array systems such as reliability, rapid delivery, and accurate result production in comparison of other labelled techniques. Label-free array systems are biosensors that use various physical and chemical techniques to detect biomolecular interactions without the need for labels or tags. These systems have various applications in drug discovery, diagnostics, and fundamental biological research.

The key component of label-free array systems is the sensor surface, which is coated with a functional layer that interacts with the biomolecules of interest. The interaction between the biomolecules and the sensor surface results in a change in the physical or chemical properties of the sensor, such as refractive index, mass, or charge. These changes can be measured and analyzed to determine the concentration, affinity, kinetics, and specificity of the biomolecular interaction.

Techniques such as biochips or microarrays, mass spectroscopy, and other advanced techniques are utilized for detecting clinical micro-organisms. The manufacturers are creating specifically imaging biosensors which can be incorporated into microplates to detect the cell lines, molecules, and proteins. When a sample containing the target micro-organisms is added to the biochip, the probes on the surface bind to their complementary targets, resulting in a detectable signal. Biochips or microarrays can be used for the identification, quantification, and characterization of clinical micro-organisms, including bacteria, viruses, and fungi. For instance, microarrays can detect antibiotic-resistant genes in bacteria, viral RNA in blood samples, and fungal antigens in serum.

Also, several other advanced techniques have been developed and utilized for the detection of clinical micro-organisms using label-free array systems. These techniques such as  surface-enhanced Raman spectroscopy (SERS), electrochemical impedance spectroscopy (EIS), and colorimetry. SERS is a vibrational spectroscopy technique that can enhance the Raman signal of molecules on a metallic surface, allowing for the detection of trace amounts of micro-organisms. EIS is an electrochemical technique that measures the changes in the impedance of a sensor surface when micro-organisms bind to the functional layer, enabling their detection. Colorimetry is a simple and low-cost technique that uses changes in color to detect micro-organisms, such as bacterial colonies on agar plates. Thus, label-free array systems offer a promising platform for the rapid and accurate detection of clinical micro-organisms.

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Label-free array systems in disease diagnosis is the identification of disease-specific signatures. These signatures are patterns of biomolecules that are characteristic of a particular disease or condition. By analyzing the molecular content of a sample using label-free array systems, researchers can identify disease-specific signatures that can be used for diagnosis and monitoring. For example, a label-free array system could be used to identify a unique protein signature in the blood of patients with Alzheimer's disease, allowing for earlier detection and improved treatment outcomes.

Additionally, Label-free array systems can also be used to monitor disease progression in real-time. By analyzing biomolecules in a sample over time, researchers can track changes in disease activity and response to treatment. For instance, a label-free array system could be used to monitor changes in the levels of specific proteins in the blood of a patient with cancer, allowing clinicians to adjust treatment strategies as needed. Moreover, the utilization of techniques such as nanofluidic array, for label free detection of biomolecules is driving the market growth and is anticipated to fuel in the forecast period.

The key market players are expanding their portfolio and are thus driving through expanding the Label-Free array systems via mergers & acquisitions. For instance, In November 2018, Agilent technologies, Inc took over ACEA Biosciences (ACEA) and thereby expanded their portfolio segment by including Label-Free array systems.

Based on type, the market is segmented into surface plasmon resonance, bio-layer interferometry, cellular dielectric spectroscopy, and others. The surface plasmon resonance segment is dominating the market in 2022, and is expected to hold the highest market share in the forecast period. Surface plasmon resonance is an extensively used technique and is a substitute to single or dual color labelling techniques. SPR technique is highly utilized in antigen-antibody reaction in protein microarray, and kinetic analysis.

Based on the application, the market is segmented into drug discovery, protein interface analysis, antibody characterization, and others. The drug discovery application segment dominated in 2022 and is anticipated to do the same in the forecast period. This is on account of rising use of label-free array systems in drug discovery, increased Research and development and growing investment for new drug development in the pharmaceutical & biotechnological industries. Also, growing applications of label-free array systems in drug discovery is propelling the market growth.

Major companies operating in the Global Label-Free Array Systems Market are:

  • Illumina, Inc.
  • Thermo Fisher Scientific, Inc.
  • Agilent Technologies, Inc.
  • PerkinElmer, Inc.
  • Merck KGaA
  • Danaher Corporation
  • Bio-Rad Laboratories, Inc.
  • F. Hoffmann-La Roche AG
  • Becton, Dickinson and Company
  • Sartorius AG

Companies operating in the market are following strategies such as continuously innovating tools to improve image quality and creating specialized clinical tools to help the patients see more anatomical detail with greater certainty, enabling them to provide the best possible patient care, to stay competitive and have an edge over other players operating in the industry.

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North America region is dominating the Label-Free Array Systems Market in recent years, attributed to the increased research & development regarding drug discovery and disease diagnosis. Besides, large number of research centers, diagnostics, and pharmaceutical companies in the region, rising investment for drug discovery and development is adding to market growth.” said Mr. Karan Chechi, Research Director with TechSci Research, a research based global management consulting firm.

Label-Free Array Systems Market – “Global Industry Size, Share, Trends, Competition, Opportunity, and Forecast, 2018-2028, Segmented By Type (Surface Plasmon Resonance, Bio-layer Interferometry, Cellular Dielectric Spectroscopy, Others), By Application (Drug Discovery, Protein Interface Analysis, Antibody Characterization, Others), By End user (Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, Contract Research Organizations, Others), By Region and Competition”, has evaluated the future growth potential of Label-Free array systems market and provides statistics & information on market size, structure, and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in global Label-Free array systems market. 

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