Humanized Mice Model Market to Grow with a CAGR of 9.80% through 2029
Rising demand for personalized medicine and growing
pipeline of pharmaceutical and biopharmaceutical companies is to drive the
Global Humanized Mice Model Market growth in the forecast period, 2025-2029.
According to
TechSci Research report, “Humanized Mice Model Market – Global Industry
Size, Share, Trends, Competition, Forecast & Opportunities, 2029”,
the Global Humanized Mice Model Market stood at USD 1.15 billion in 2023 and is
anticipated to grow with a CAGR of 9.80% in the forecast period, 2025-2029. Factors
such as the continuous advancements in mice models, the escalating demand for
personalized medicine, and the expanding pipeline of pharmaceutical and
biopharmaceutical companies are fueling the growth of the mice model market.
The utilization
of mice models for the identification of immunodeficiency disorders, cancers,
and other rare diseases, coupled with the increase in research and development
activities conducted by pharmaceutical and biotechnology companies, has
contributed to the growing demand for personalized mice models. The
continuous support and initiatives from governments and private sectors for
research on mice models, along with the adoption of modified medicines, have
further fueled this demand. Technological advancements, the rising prevalence
of cancer, ongoing research and development activities, and the increasing
adoption of personalized medicines are key factors projected to drive the
Global Humanized Mice and Rat Model Market. Notably, government investments
play a crucial role in stimulating this market.
Mice models are
considered to be among the most effective small animal models for studying
various infectious diseases, including hepatitis B virus (HBV), hepatitis C
virus (HCV), Zika virus, and cytomegalovirus (CMV), among others. Their use in
pre-clinical research has significantly contributed to our understanding of
viral infections and the development of potential treatments. In a recent
article titled "Novel App knock-in mice model shows key features of
amyloid pathology and reveals profound metabolic dysregulation of
microglia," published in June 2022, it was highlighted that the genetic
engineering of novel mice models using knock-in approaches has helped overcome
some of the limitations associated with genetic mutations. This approach opens
up new possibilities for studying disease mechanisms and developing targeted
therapies. The article also emphasized the importance of open-access mice
models as valuable resources for studying disease-relevant biology.
Mice possess several advantages over other model organisms. Their genome is
remarkably similar to the human genome, sharing about 99% of its genetic
sequence. This genetic similarity enables researchers to translate findings
from mice studies to human diseases more effectively. Mice offer
a robust genetic and molecular toolkit, allowing for sophisticated manipulation
and analysis of genes and proteins. Their small size makes them a
cost-effective model for large-scale, high-throughput research. In an article
titled "How Necessary are Animal Models for Modern Drug Discovery?"
published in September 2021, it was noted that advancements in human tissue
engraftment techniques and the development of humanized mice models have
significantly contributed to our understanding of human diseases. These
humanized mice models, with transplanted tissues that can perform close to
normal organ and tissue functions, offer a valuable platform for studying
disease mechanisms and evaluating potential therapeutic interventions.
Considering the numerous advantages and applications of mice models, their
demand is expected to continue growing, thereby driving the overall market
growth in the foreseeable future.
Humanized mice
models have been developed to overcome limitations of traditional mice models,
such as differences in immune systems. These models are crucial in preclinical
research, as they can replicate human pathological conditions and evaluate the
effectiveness of immunotherapy approaches. They are used in studies of
infectious diseases, transplantation, regenerative medicine, and cancer
biology. Humanized mice models have also played a significant role in the
development of vaccines and antibody-based therapies for COVID-19. Scientists
have created a triple immunodeficient humanized mice model that engrafts CD34+
cord blood and supports the production of human immune cells expressing ACE2,
the receptor used by the coronavirus to enter human cells. These models, along
with others developed since the COVID-19 outbreak, are expected to enhance our
understanding of SARS-CoV-2 infection, the efficacy of antiviral therapies, and
aid in the development of effective drugs for treatment and prevention of this
disease.
Rapid
technological advancements and genetic engineering of the mice genome have
contributed to significant revenue growth in this market. This trend is
expected to continue in the future.
Browse over XX market data Figures spread through XX Pages and an in-depth TOC on "Global Humanized Mice Model Market”
The Global Humanized
Mice Model Market is segmented into type, application, end user, regional
distribution, and company.
Based on its application,
the market is segmented into oncology, immunology & infectious diseases,
toxicology, and others. The Oncology segment is projected to hold a significant
market share throughout the forecast period. The application of mice models in
oncology is anticipated to experience substantial growth, driven by the
increasing burden of cancer and the adoption of mice models in drug and vaccine
development research. The use of mice models in oncology has gained momentum
for drug discovery and therapeutics development, with several advancements
expected to drive market growth. Notably, in February 2021, ExpreS2ion Biotech
Holding and the University of Bologna collaborated on a research agreement to
test the novel HER2-cVLP breast cancer vaccine program, including the lead
candidate ES2B-C001, using proprietary state-of-the-art breast cancer mice
models. Consequently, the application of mice models is poised to revolutionize
drug discovery research, particularly in developing and validating various
cancer therapies, including cancer immunotherapy, thereby fueling segment
growth during the forecast period.
Based on region,
North America segment is expected to grow during the forecast period. North
America is expected to experience growth throughout the forecast period and maintain
its dominance in the market. Among the countries in the region, the United
States is leading the market due to factors such as increased healthcare
expenditure, rising research and development activities, and a growing
prevalence of communicable and non-communicable diseases. The
primary driver for the mice model market in the United States is the increasing
geriatric population. Market players in the country are engaged in various
activities, including collaborations and agreements, which are expected to
drive market growth during the forecast period.
Major companies
operating in Global Humanized Mice Model Market are:
- Allentown LLC
- Charles River Laboratories
International, Inc.
- HBM Holdings
- Horizon Discovery Group plc
- Ingenious Targeting Laboratory
- Janvier Labs
- Trans Genic Inc.
- PolyGene AG
- Aragen Life Sciences Ltd.
- The Andersons, Inc.
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“The humanized
mice model market is expected to experience significant growth in the coming
years. This growth can be attributed to the rising demand for personalized
medicines that are developed using animal models, particularly mouse models. In
this approach, human tissues are transplanted into immunodeficiency models,
allowing researchers to observe disease manifestations. These models are then
treated with different drugs or gene therapies to identify the most suitable
treatment options. The ultimate goal is to provide patients with tailored and
customized drugs, thereby enhancing their overall healthcare outcomes. As a
result, these advancements are anticipated to have a considerable impact on the
global market, influencing various factors such as research and development,
pharmaceutical manufacturing, and patient care.,” said Mr. Karan Chechi,
Research Director, TechSci Research, a research-based management consulting
firm.
“Humanized Mice Model Market - Global Industry Size,
Share, Trends, Opportunity, and Forecast, Segmented By Type (Humanized Mice
Models, Humanized Rat Models), By Application (Oncology, Immunology &
Infectious Diseases, Toxicology, Others), By End User (Pharmaceutical &
Biotechnology Companies, Contract Research Organizations, Academic &
Research Institutions), By Region and Competition, 2019-2029F”, has evaluated
the future growth potential of Global Humanized Mice Model Market and provides
statistics & information on market size, structure and future market
growth. The report intends to provide cutting-edge market intelligence and help
decision makers take sound investment decisions. Besides, the report also
identifies and analyzes the emerging trends along with essential drivers,
challenges, and opportunities in Global Humanized Mice Model Market.
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