Press Release

United States Hereditary Angioedema Therapeutics Market to Grow with a CAGR of 4.28% through 2031

Rising awareness and improved diagnosis is expected to drive the United States Hereditary Angioedema Therapeutics Market in the forecast period.


According to TechSci Research report, “United States Hereditary Angioedema Therapeutics Market By Treatment, By Route of Administration, By End-use, Region and Competition, Forecast and Opportunities, 2021-2031F”, the United States Hereditary Angioedema Therapeutics Market will grow from USD 883.56 Million in 2025 to USD 1136.17 Million by 2031 at a 4.28% CAGR. Recent years have seen significant advances in the treatment of Hereditary Angioedema (HAE), a rare genetic disorder characterized by recurrent, severe swelling in various body parts. In the United States, heightened awareness of HAE among healthcare professionals and the public has led to improved diagnosis and to an expanded patient population requiring treatment. Traditional therapies such as C1 inhibitor replacement and bradykinin receptor antagonists, while effective, have limitations. However, recent drug developments, including subcutaneous and oral options, offer enhanced convenience, fewer side effects, and improved patient experiences. The US FDA's proactive evaluation and approval of breakthrough therapies, such as lanadelumab (Takhzyro), have revolutionized HAE management. These medications provide long-term prevention of attacks, reducing the frequency of administration and improving disease control, leading to fewer hospitalizations and better patient outcomes. 


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The HAE therapeutics market has shifted towards a more patient-centric approach, acknowledging the specific requirements of individuals with HAE and customizing treatments to enhance their quality of life. This strategy extends beyond the development of more convenient therapies to encompass patient support initiatives, educational materials, and advocacy campaigns that empower patients and their families. Ensuring that patients are educated and involved in managing their condition is crucial for achieving sustainable long-term outcomes.

The United States Hereditary Angioedema Therapeutics Market is segmented into treatment, route of administration, end-use, regional distribution, and company. 

Based on the end use, Prophylaxis segment emerged as the dominant segment in the United States market for United States Hereditary Angioedema Therapeutics Market in 2023. This is primarily due to the increasing recognition of the importance of preventive measures in managing HAE. Prophylactic treatments aim to minimize the frequency and severity of attacks, thus improving patients' overall quality of life and reducing the need for emergency interventions. Advancements in therapeutic options, such as long-acting monoclonal antibodies, have made prophylactic regimens more attractive and feasible for patients, thereby further strengthening this segment's dominance in the market.

By region, the Midwest segment emerged as the dominant segment in the United States Hereditary Angioedema Therapeutics Market in 2023. This is because the region hosts a substantial patient population, including those requiring specialized HAE care, resulting in increased demand for therapeutics. The presence of renowned treatment centers and experts in the Midwest attracts patients seeking advanced care. Several pharmaceutical companies focused on rare diseases, including HAE, are headquartered in or have a significant presence in the Midwest. This concentration fosters research, development, and commercialization, thereby driving market growth in the region.

Major companies operating in United States Hereditary Angioedema Therapeutics Market are:

  • BioCryst Pharmaceuticals, Inc.
  • Ionis Pharmaceuticals, Inc.
  • Seqirus Pty Ltd. (CSL Limited)
  • Attune Pharmaceuticals, Inc.
  • Adverum Biotechnologies, Inc.
  • KalVista Pharmaceuticals, Inc.
  • Takeda Pharmaceutical Company Limited
  • Pharming Healthcare N.V.
  • Sanofi AG
  • Cipla Ltd. 


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“The United States Hereditary Angioedema Therapeutics (HAE) market is primed for notable expansion in the foreseeable future. Sustained research and development efforts continually yield novel therapies with enhanced efficacy and patient-friendliness. From advanced monoclonal antibodies to oral medications and prophylactic treatments, HAE patients now have a diverse range of options for managing their condition. The heightened awareness, early diagnosis, and genetic testing are refining the detection of HAE cases, facilitating prompt intervention and tailored treatment strategies. Embracing a patient-centered approach is increasingly prevalent, nurturing a climate of empowerment and self-care among individuals grappling with HAE” said Mr. Karan Chechi, Research Director with TechSci Research, a research-based management consulting firm.

United States Hereditary Angioedema Therapeutics Market By Treatment, By Route of Administration, By End-use, Region and Competition, Forecast and Opportunities, 2021-2031F”, has evaluated the future growth potential of United States Hereditary Angioedema Therapeutics Market and provides statistics & information on market size, structure and future market growth. The report aims to provide cutting-edge market intelligence and help decision-makers make sound investment decisions. Additionally, the report identifies and analyzes emerging trends, essential drivers, challenges, and opportunities in the United States Hereditary Angioedema Therapeutics Market.



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