Press Release

Phenylketonuria Treatment Market to grow with a CAGR of 8.61% through 2031

Increasing healthcare infrastructure and a supportive regulatory environment are the major drivers for the Global Phenylketonuria Treatment Market in the forecast period, 2027-2031F

 

According to TechSci Research report, “Phenylketonuria Treatment Market - Global Industry Size, Share, Trends, Competition, Opportunity and Forecast, 2031F”, the Global Phenylketonuria Treatment Market will grow from USD 581.04 Million in 2025 to USD 953.73 Million by 2031 at an 8.61% CAGR.  This may be due to collaborations and partnerships among leading companies, which enable a diverse approach to integrating individual companies' expertise and strengthening their market positions.

Advancements in the treatment of Phenylketonuria (PKU) have been ongoing, with a focus on improving the management of this genetic disorder. PKU is characterized by the inability to metabolize phenylalanine, an amino acid found in protein-containing foods. The treatment aims to maintain safe blood phenylalanine levels while ensuring adequate nutrition. Glycomacropeptide (GMP)- based protein substitutes have been developed as alternatives to traditional amino acid-based medical foods.

GMP is a naturally low-phenylalanine protein derived from cheese whey. Advances in the formulation of protein substitutes have led to more palatable and more convenient products, thereby improving patient compliance. Companies have introduced low-protein food products specifically designed for patients with PKU, making it easier to adhere to dietary restrictions. PEGylated Phenylalanine Ammonia Lyase (PAL) has been developed to help break down excess phenylalanine in the blood. These therapies are administered by injection and can be effective in managing PKU.

An uncommon hereditary condition, phenylketonuria (PKU), is characterized by elevated blood levels of the amino acid phenylalanine. Proteins derived from food and nutrition include the amino acid phenylalanine. In the human body, phenylalanine hydroxylase catalyzes the conversion of phenylalanine to the amino acid tyrosine. Seizures, mental illnesses, and several other untreated disorders can be brought on by an excess of phenylalanine in the blood.

 

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Global Phenylketonuria Treatment Market segmentation is based on route of administration, product, distribution channel, region and company.

Based on Distribution Channel, The Global Phenylketonuria (PKU) Treatment Market is witnessing rapid growth, with the Online Pharmacies segment emerging as the fastest-growing during the forecast period. The increasing preference for convenience, privacy, and accessibility is driving patients and caregivers toward digital platforms for purchasing PKU medications and specialized low-protein medical foods. Online pharmacies offer a wider range of treatment options, facilitate easy price comparisons, and enable discreet transactions—all of which are highly valued in managing rare conditions such as PKU. As digital health adoption accelerates, this segment is experiencing significant momentum and expanding rapidly.

Based on Region, the Asia-Pacific region is expected to experience the fastest growth in the Global Phenylketonuria Treatment Market. Awareness of rare genetic disorders like PKU has been growing in the Asia-Pacific region. As awareness increases, more individuals may be diagnosed with PKU through newborn screening programs and genetic testing, driving demand for treatment. The Asia-Pacific region is home to a significant portion of the world's population. As the population grows, so does the number of individuals potentially affected by PKU, contributing to increased demand for PKU treatments. Many countries in the Asia-Pacific region are experiencing rapid economic growth, leading to increased healthcare infrastructure and resources. This growth can improve access to specialized care and PKU treatments


Some of the major companies operating in the Global Phenylketonuria Treatment Market include:

  • BioMarin Pharmaceutical Inc.
  • Synlogic, Inc.
  • Retrophin, Inc.
  • Daiichi Sankyo Company, Limited
  • Codexis, Inc.
  • SOM Innovation Biotech SL
  • Homology Medicines, Inc.


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“North America is expected to drive significant demand for phenylketonuria (PKU) treatment, fueled by increasing awareness, advanced healthcare infrastructure, and supportive government initiatives. The presence of well-established pharmaceutical companies committed to enhancing patient well-being further accelerates market growth. Ongoing research and development efforts, including innovative drug formulations and improved dietary management solutions, contribute to the expansion of treatment options. Rising newborn screening programs and early-diagnosis rates increase demand for effective PKU therapies. These factors, combined with a highly competitive market landscape, are expected to drive substantial growth in the global PKU treatment market during the forecast period," said Mr. Karan Chechi, Research Director of TechSci Research, a research-based Global management consulting firm.

"Phenylketonuria Treatment Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Route of Administration (Oral, Parenteral), By Product (Dietary Supplement, Drugs), By Distribution Channel (Hospital Pharmacies, Online Pharmacies, Pediatric Clinics), By Region & Competition, 2021-2031F", evaluated the future growth potential of Global Phenylketonuria Treatment Market and provides statistics & information on market size, structure, and future market growth. The report aims to provide innovative market intelligence and support decision-makers in making sound investment decisions. Additionally, the report identifies and analyzes emerging trends, as well as essential drivers, challenges, and opportunities, in the Global Phenylketonuria Treatment Market.

 

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