Press Release

Organ-on-Chip Market to Grow with a CAGR of 25.61% through 2028

Increasing demand for electronic chip miniaturization and accelerating healthcare expenditure in developed countries is expected to drive the Global Organ-on-Chip Market growth in the forecast period, 2024-2028.

 

According to TechSci Research report, “Organ-on-Chip Market – Global Industry Size, Share, Trends, Competition Forecast & Opportunities, 2028”, the Global Organ-on-Chip Market stood at USD 388.20 million in 2022 and is anticipated to grow with a CAGR of 25.61% in the forecast period, 2024-2028. The organ-on-chip market is experiencing significant growth due to several key factors. These include a notable increase in research funding dedicated to the development of this technology, growing partnerships and collaborations between pharmaceutical companies and product manufacturers, and a rising demand for early drug detection.

Organs-on-chips technology offers numerous advantages, such as its cost-effective production, ability to test a wide range of drug concentrations, and its three-dimensional nature compared to traditional petri dishes. These factors contribute to its expanding application across various fields, further driving the development of market revenue.

 

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Organs-on-chips technology offers several advantages, such as cost-effective production, the ability to test a wide range of drug concentrations, and the three-dimensional aspect compared to traditional petri dishes. These attributes have led to its increased application in various fields, driving market revenue growth. Additionally, by replicating the micro-environment of human cells, including temperature, oxygen levels, and pH, organ-on-chip technology maintains a realistic physiological setting. The use of microfluidics makes these devices a unique research solution, as they are portable, user-friendly, and can be mass-produced, further contributing to market demand and revenue growth.

Several factors contribute to the market's revenue growth, including the growing emphasis on developing alternatives to animal testing, increased research funding for organ-on-chip technology, and collaborations between organ-on-chip producers and pharmaceutical companies. The expanding applications of organ-on-chip devices in the healthcare sector, particularly in drug screening, and the rising demand for lung- and kidney-based organ culture are expected to drive market revenue growth in the future. However, the market faces challenges such as the increasing costs associated with organ-on-chip devices, limitations of certain materials used in production, and the need for improved substrate materials.

Microchips are gaining prominence due to technological advancements in medical equipment, enabling miniaturization and reducing material requirements. Microfluidic chips play a crucial role in organ-on-a-chip systems, facilitating the growth of miniature tissues that closely resemble natural tissues. The concept behind organ-on-chip technology is to create a micron-sized in vitro environment that mimics the behavior and composition of an actual organ.

The aging population and the rise in chronic diseases are expected to drive the demand for organ-on-chip technology. Additionally, increasing healthcare costs worldwide contribute to market growth. According to a World Health Organization (WHO) report, healthcare spending is rapidly increasing, especially in low- and middle-income countries. The rising prevalence of cardiovascular diseases has also led to increased demand for organ-on-chip devices, which accurately simulate the human cardiovascular system and offer valuable insights for personalized cardiovascular medication and improved patient care. Ongoing research, drug application, and efficacy testing will be key drivers for the organ-on-chip market in the forecast period.

Organ-on-chip technology has the potential to provide early evaluation of human-specific data on drug efficacy and toxicity, offering significant possibilities for faster and easier detection. The technology is evolving rapidly as market participants explore newer models. With the ability to grow human cells in micro-controlled environments, organ-on-chip devices can simulate multiple organs on a single chip, providing detailed insights into the functioning of the human body. These factors are expected to drive the growth of the organ-on-chip market in the coming years.

 

The Global Organ-on-Chip Market is segmented into type, offering, material type, application, end user, regional distribution, and company.

Based on type, the lung-related application is expected to demonstrate substantial growth throughout the forecast period. The lung-on-chip technology, a sophisticated three-dimensional model of a functioning human lung on a microchip, consists of human lung and blood vessel cells. It has the ability to anticipate the absorption of airborne nanoparticles and replicate the inflammatory response caused by microbial pathogens. Additionally, it can evaluate the impact of environmental toxins, assess the absorption of aerosolized therapeutics, and assess the safety and efficacy of novel drugs. By integrating microfabrication techniques with contemporary tissue engineering, the lung-on-chip approach presents a novel in-vitro method for drug screening, closely mimicking the complex mechanical and biochemical behavior of the human lung.

Furthermore, the development of innovative solutions to address pulmonary diseases assumes paramount importance, given their high prevalence worldwide. According to the World Health Organization's Global Tuberculosis Report 2022, an estimated 10.6 million individuals contracted tuberculosis (TB) globally in 2021, equivalent to 134 cases per 100,000 population. The incidence rate of TB is projected to have increased by 3.6% between 2020 and 2021. Consequently, the escalating incidence of pulmonary diseases, such as tuberculosis, fuels the demand for organ-on-chip technology in disease management, thereby driving market growth during the study period. Therefore, despite its proven efficacy, the lung-on-chip technology may benefit from further engineering, potentially involving muscle cells, to facilitate the evaluation of treatment effects on the lungs. This could potentially contribute to further expansion of the market.

Based on region, North America segment is expected to grow during the forecast period. North America is projected to demonstrate the largest market share throughout the forecast period. The United States holds the highest market share in the North American region, primarily due to increased investment in research and development for drug discovery and biotechnology. It asserts dominance in the organ-on-chip market, attributed to factors such as a wide range of services offered by major players, including customized chip design with specific organ arrangements, as well as increased toxicological testing of chemicals on various types of organ cells. Significant investments from public and private institutions are being made to support research endeavors.

For instance, according to the National Institutes of Health (NIH), estimated research funding for biotechnology in the United States is projected to reach USD 7,847 million in 2021 and USD 8,142 million in 2022. This gradual increase in research funding for biotechnology contributes to the advancement of organ-on-chip research and drives market growth over the forecast period. Additionally, several initiatives in North America, such as the provision of organ-on-chip services, approvals, and product launches, contribute to market expansion. For example, in May 2022, Nikon Instruments Inc. announced the initiation of organ-on-a-chip imaging and analysis contract services in the United States, specifically targeted towards research and development for drug discovery. Similarly, in March 2021, AIM Biotech introduced a contract research service utilizing their organ-on-a-chip technology to expedite and enhance drug discovery and development. These services further broaden the scope of organ-on-a-chip imaging, thus fostering market growth. Therefore, the aforementioned factors are expected to significantly impact the growth of this market segment.

 

Major companies operating in Global Organ-on-Chip Market are:

  • Altis Biosystems
  • AxoSim Inc.
  • BiomimX SRL
  • Emulate Inc.
  • Hesperos
  • Allevi Inc.
  • InSphero AG
  • MIMETAS BV
  • Nortis Inc.
  • Hesperos, Inc.


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“There is currently a rise in the demand for organ-on-chips in drug screening, driven by several key factors. Firstly, the use of organ-on-chips helps reduce employee healthcare costs, improve morale, productivity, and performance, and decrease absenteeism, accidents, downtime, turnover, and theft. Additionally, there is a growing demand for lung and kidney-based organ culture devices. Moreover, the availability of laboratory-engineered functional organs worldwide is increasing. This, coupled with the escalating demand for alternatives to animal testing through research activities on organ-on-chip devices for new drug development, is propelling market growth. Furthermore, advancements in cell biology, microfabrication, and microfluidics have led to the rising adoption of organ-on-chips technology, offering lucrative growth opportunities for industry investors. The healthcare industry also benefits from the application of organ-on-chips devices, enabling real-time imaging and in vitro analysis of biochemical, genetic, and metabolic activities of living cells in functional tissues. Lastly, key market players are heavily investing in research and development (R&D) activities to develop new solutions for treating pulmonary diseases, further catalyzing the demand for organ-on-chips technology.,” said Mr. Karan Chechi, Research Director with TechSci Research, a research-based management consulting firm.

Organ-on-Chip Market Segmented By Type (Liver, Heart, Lung, Kidney, Others), By Offering (Products v/s Services), By Material Type (Polymer, PDMS, Glass, Silicon, Others), By Application (Physiological Model Development, Drug Discovery, Toxicological Research, Molecular Biology, Others), By End User (Pharmaceutical & Biotechnology Companies, Academic & Research Institutes, Others), By Region and Competition, Forecast & Opportunities, 2018-2028F”, has evaluated the future growth potential of Global Organ-on-Chip Market and provides statistics & information on market size, structure and future market growth. The report intends to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges, and opportunities in Global Organ-on-Chip Market.

 

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