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Product Review: Bausch+Lomb LuxGood and LuxSmart Intraocular Lens

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Healthcare | May, 2021

Cataract affects over 50 million people globally, causing 33% of total visual impairment and 51% of total blindness. Thanks to intraocular lens (IOL) technology, blindness from cataract can be reversed with presbyopia correction. Rapid innovation in intraocular lens technology has led to a significant enhancement in refractive outcomes. The popular desire for spectacle independence post-cataract surgery is an increasingly prevalent aspect of premium cataract surgery practice, which has now evolved into a lens-based refractive surgery. Recently, Bausch+Lomb launched the company’s first Extended Depth of Focus intraocular lens, LuxSmartTM, and a new and improved monofocal IOL, LuxGoodTM featuring pre-loaded delivery systems. Incorporating Pure Refractive Optics (PRO) technology, the IOL lenses ensure no diffraction areas to prevent the occurrence of dysphotopsia, a common phenomenon associated with premium IOLs that tend to compromise the vision of the patients. With the introduction of LuxSmart and LuxGood in the premium cataract options portfolio, Bausch+Lomb now offers a comprehensive range of innovation IOLs in European nations to meet the growing demand. 

 

The LuxSmart preloaded IOL and its monofocal version LuxGood is available both with and without a proprietary acrylic hydrophobic cross-linked copolymer material along with a UV absorber to protect eyes against the UV light. The new technology IOL has been designed to provide consistent visual outcomes. The four-point fixation design and 360°posterior square-edges of IOL help to achieve lens centration, resist posterior capsular opacification, ensure rotation stability, and improve refractive predictability. 

 

Key features of LuxGood and LuxSmart IOL

·         Monofocal periphery

Monofocal intraocular lenses correct spherical ablation and provide better overall vision than conventionally used IOLs. With improved contrast sensitivity, enhanced functional vision, and superior night driving ability, the monofocal IOLs become the preferred choice for dramatically enhancing distance vision along with spectacular clarity.

·         Acrylic Hydrophobic IOL

Acrylic hydrophilic IOLs are widely used in small-incision cataract surgery because of their high stability rate and better capsular compatibility. Since the hydrophilic acrylic material has water content and a low refractive index, it reduces the risk of dysphotopsia and other unwanted visual phenomena. Also, the IOLs are resistant to damage, possess good optical clarity, and protect from biocontamination. Due to their good uveal biocompatibility and a lower rate of Opacification, hydrophilic acrylic IOLs are highly preferred by ophthalmologists.

·         Pre-loaded Single Injector

The pre-loaded single injection IOL offers the advantage of consistent IOL folding and implantation with sterility along with reducing the possibility of lens damage. The single-use disposable devices pose less risk of postoperative endophthalmitis and improve post-surgical outcomes. The preloaded delivery systems are easy to use, reduce complications, and aid in improving the efficiency of eye surgeries. The single-step fully loaded injection prevents cross-contamination and mishandling and produces more predictable IOL delivery with less wound stretching.

·         UV light protection

Special transmission curves of LuxSmart crystal (393.5 nm) and LuxSmart (397 nm) protects against the damaging UV light. UV light has high energy and a short wavelength, and it is emitted by electronic screens of laptop or phone and some indoor light, which tend to have a negative impact on visual functioning. Just like human eyes can filter out this part of the visible spectrum, the IOLs designed with short-wave light filtering reduce transmission of UV radiation, which could potentially lead to retinal damage post-cataract surgery.

·         EDOF Center

The 2-mm EDOF center integrating 4th and 5th orders of spherical aberration of opposite signs increase the subjective depth of field. Extended range of vision IOL is a new technology for the treatment of presbyopia-correcting lenses, which enhances the depth of focus and eliminates overlapping of near and far images caused by traditional monofocal IOLs. The EDOF IOLs provide better optical quality and provide excellent intermediate vision but provide poor quality of vision for near distances.

·         Square edge on posterior chamber IOL

The 360-degree continuous square edge on the posterior surface delivers optimized effectiveness against posterior capsule opacification and prevents epithelial lens cell migration. 

·         4-point fixation haptic design

The four-point haptic design of LuxGood and LuxSmart enables good centration, rotational stability and is suitable for the correction of corneal astigmatism. The four-point haptic design is preferred over the two-point haptic design to avoid IOL decentration and capsular contraction.

·         Aberration free aspheric optic

The aberration-free aspheric IOL offers a better quality of vision to all the patients as it prevents additional spherical aberration into the eye and provides better contrast in low-light conditions. The aberration-free design is suitable for all patients irrespective of corneal shape and its performance is unaffected by optical misalignment, IOL, or pupil decentration.

Other Newcomers in Intraocular Lens Market

Three unique and non-diffractive, non-multifocal lenses have been recently introduced in the market for the correction of presbyopia. Let us look at the unique design and features of the three newcomers in the Intraocular lens market. 

 

·         Acrysof IQ Vivity (Alcon)

The novel, non-diffractive extended depth-of-focus intraocular Vivity lens uses Alcon’s proprietary X-Wave technology. The 6-mm biconvex, wavefront-shaping and aspheric optic lens is made of hydrophobic copolymer with UV and blue light filtration. The lens looks like a monofocal cousin until the light hits the central optic element. The elevation and curvature change in the central optic element of the Vivity lens affect the wavefront differently and helps to achieve an extended range of vision. The lens is suitable for anyone with healthy or imperfect eyes, seeking an extended range of vision, or is intolerant to the potential for dysphotopsias.  

 

·         Tecnis Eyhance (Johnson & Johnson Vision)

Eyhance is a 6-mm biconvex monofocal lens with an aspheric anterior surface made of UV-blocking hydrophobic acrylic. Johnson & Johnson Eyhance has a frosted, continuous 360-degree posterior square edge and provides 30% enhancement in contrast in low-light conditions. The lens offers an increased depth of focus when compared to a standard monofocal and has a low dysphotopsia profile. Eyhance delivers true intermediate vision for patients looking for a broader range of vision but is not able to afford that with an EDOF lens. Eyhance is designed for a smooth and continuous shift in power from the periphery to the center of the lens, which is not visible to the naked eye. The Eyhance lens is refractive and reduces spherical aberration to zero to improve intermediate vision. 

 

·         The RayOne EMV (Rayner Global)

The RayOne EMV has been designed for patients who desire spectacle independence but are not ideal candidates for diffractive trifocals. The lens with a preloaded intraocular lens injection system is a cost-effective solution. The FDA-approved IOL is the future standard of IOL technology as it provides the greatest range for vision with fewer visual side-effects. The RayOne EMV is specially created for the monovision treatment and provides an extra depth of focus offering a smoother transaction between the dominant and non-dominant eye. 

 

Conclusion 

With the rapid innovation in the sophisticated intraocular lens, modern cataract surgery would continue to advance. Bausch+Lomb LuxGood and LuxSmart consist of the most advanced technologies and are suitable for a wide range of patients seeking vision correction. Both the lenses deliver excellent patient outcomes and patient satisfaction due to their unique design, optical quality, refractive ability, and absence of dysphotopsic phenomenon. In the coming years, change of refractive power as per individual needs would help to enhance the outcomes. The rising prevalence of eye disorders and growing demand for eye surgeries are expected to further boost the global eye care market. 

 

According to TechSci research report on Global Eye Care Market By Product Type (Eyeglasses, Contact Lens, Intraocular Lens, Eye Drops, Others), By Coating (Anti-Glare, UV coating, Others), By Lens Material (Normal Glass, Polycarbonate, Trivex, Others), By Distribution channel (Retail stores, E-commerce, Clinics, Hospitals), By Region, Forecast & Opportunities, 2026”, the global eye care market is expected to grow at a formidable CAGR of 6.31% owing to the increasing awareness towards eye health and rising incidences of eye disorders globally. Besides, increasing adaptability of electronic devices and advent of innovative technologies in the eye treatment are fuelling the growth of global eye care market.

 

According to another TechSci research report on “Global Contact Lenses Market By Modality (Reusable, v/s Disposable), By Design (Spherical, Toric, Multifocal & Others), By Material Type (Silicon hydrogel, Hydrogel, Gas Permeable & others), By Application (Corrective, Therapeutic, Cosmetic & others), By Distribution (Retail Stores, Hospitals & Clinics, Online,) By Region, Competition, Forecast & Opportunities, 2026”, the global lens market was valued at USD13.73 billion and is expected to grow at a formidable rate due to the growing geriatric population and increasing incidences of eye related disorders. Besides, the increasing personal disposable income and changing consumer preferences are propelling the demand for global contact lens market in the coming years.