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AtomVie Opens North America''s Largest Radiopharmaceutical CDMO Facility

AtomVie Opens North America''s Largest Radiopharmaceutical CDMO Facility

USD160M+ greenfield plant in Hamilton, Ontario delivers a tenfold capacity expansion, scaling the company from clinical trials to commercial-scale radiopharmaceutical manufacturing.

September 6, 2026 | Hamilton, Ontario, Canada: AtomVie Global Radiopharma, a Canadian contract development and manufacturing organization (CDMO) specializing in radiopharmaceuticals, celebrated the grand opening of its new purpose-built manufacturing facility at 10 Aeropark Boulevard in Hamilton, Ontario. Representing an investment of more than US$160 million, the 72,300-square-foot plant is now the largest single-site CDMO facility for radiopharmaceutical development in North America and delivers more than a tenfold increase in AtomVie's manufacturing capacity. Purpose-built to support lifecycle growth, the facility enables seamless progression from early-stage development to commercial manufacturing, with customizable space reserved for clients' future requirements. AtomVie, a spinout of McMaster University's Centre for Probe Development and Commercialization, expects to grow its workforce beyond 200 employees by the end of 2026 as the site scales toward full operations, building on a track record of more than 70 clinical development and technology transfer programs, over 1,000 cGMP batches manufactured, and more than 4,400 cGMP doses delivered to patients across 28 countries with a delivery success rate above 99%.

According to Bruno Paquin, Chief Executive Officer, AtomVie Global Radiopharma, “This Grand Opening represents the next chapter of AtomVie's journey and a proud milestone for Canadian innovation in nuclear medicine. Our new purpose-built facility amplifies a proven track record of reliable global delivery and deep scientific expertise, enabling us to support the development and commercialization of our partners' pipelines. Above all, it advances our purpose of transforming patients' lives by delivering high-quality radiopharmaceuticals to those who need them, all around the world."

According to TechSci Research, AtomVie's Hamilton facility signals a structural shift in the radiopharmaceutical value chain: manufacturing capacity, rather than clinical innovation alone, is fast becoming the binding constraint on commercial growth in nuclear medicine. TechSci Research estimates that the global radiotheranostics market will expand from approximately US$11.15 billion in 2025 to US$33.98 billion by 2031, registering a CAGR of 20.41%, while the broader radiopharmaceuticals market is projected to grow from US$6.12 billion in 2025 to US$8.32 billion by 2031 at a CAGR of 5.25%. This demand surge, led by targeted radioligand therapies for oncology and a broader theranostics convergence of imaging and therapy, is colliding with a tightly constrained supply of GMP-grade manufacturing capacity.

Radiopharmaceutical production is among the most capital-intensive and technically demanding segments of pharma contract manufacturing infrastructure must accommodate specialized hot cells, radiation shielding, short-lived radioisotope logistics and stringent regulatory oversight which limits the pool of credible CDMOs able to serve late-stage and commercial pipelines. The response is a visible wave of capacity investment in North America, Europe and Asia, with AtomVie's more than US$160 million greenfield commitment illustrating the scale of capital required to compete. For biopharmaceutical partners, the strategic benefit is de-risked, scale-ready supply: the ability to transition a molecule from Phase I through commercialization on a validated platform shortens timelines that would otherwise be consumed by facility qualification at multiple sites.

For governments, the investment reinforces domestic life-sciences manufacturing resilience and high-skilled employment, a policy priority reflected in Ontario's life-sciences funding commitments. For competitors, the entry of a ten-fold capacity expansion raises the bar scale, isotope supply security (lutetium-177, actinium-225 and other emerging isotopes) and regulatory track record will increasingly differentiate the winners. Risks merit attention: capacity utilization depends on clinical pipeline progression across the industry, isotope supply remains concentrated among a handful of producers, and regulatory complexity elevates execution risk.

TechSci Research anticipates accelerating consolidation and strategic isotope-supply partnerships across the CDMO landscape, and views capacity-led investments aligned with theranostic growth such as AtomVie's as forward-looking bets on a market where scarcity of manufacturing capability, not demand, will define the next phase of competition.

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