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ADC-Focused OnCusp Therapeutics emerges with a significant $100M Series A raise

ADC-Focused OnCusp Therapeutics emerges with a significant $100M Series A raise

OnCusp Therapeutics Secures Oversubscribed USD100 Million Series A Financing to Advance Robust Portfolio of Assets for Cancer Patients.

NEW YORK: OnCusp Therapeutics, Inc., a pioneering biopharmaceutical company, is dedicated to transforming cutting-edge preclinical innovation into clinically validated treatments for cancer patients worldwide. Today, the company proudly announced the successful completion of an oversubscribed USD100 million Series A financing round, signaling strong investor confidence in its mission.

The round was co-led by Novo Holdings, OrbiMed, and F-Prime Capital, prominent names in the investment landscape. They were joined by other esteemed investors such as Sofinnova Investments, Catalio Capital Management, Marshall Wace, Forge Life Science Partners, Blackbird BioVentures, CJNV BioVenture, and more. Notably, BioTrack Capital served as a co-lead for the Seed Round, further underscoring the excitement surrounding OnCusp Therapeutics.

Since its establishment in April 2021, OnCusp Therapeutics has raised an impressive USD139 million, a testament to the compelling potential of its innovative approach. With this new injection of capital, the company aims to advance its lead candidate, CUSP06, an antibody-drug conjugate (ADC) targeting CDH6, towards clinical proof-of-concept. The funds will also support the expansion of the OnCusp portfolio and team, fostering further advancements in the field of cancer therapeutics.

CUSP06 has demonstrated strong preclinical data, showcasing its potential for best-in-class activity. Engineered with a focus on potency, "bystander effect," linker stability, and overcoming drug resistance, CUSP06 possesses differentiating attributes that could translate into higher clinical response rates and durability, all while maintaining an improved safety profile. With FDA Investigational New Drug (IND) clearance obtained in the third quarter of 2023, CUSP06 is set to embark on a first-in-human Phase I study in the United States, marking an important milestone in the journey towards potential clinical breakthroughs.

According to the Co-Founder and CEO of OnCusp Therapeutics, “We are grateful to have the trust and support from some of the most prominent global biotech investors. I am also thankful to the OnCusp team for their commitment and excellent work. We hold a strong conviction to develop innovative oncology therapies for patients. This significant Series A financing enables OnCusp to accelerate the development of CUSP06 and other game-changing therapeutics in our fight against cancer."

According to TechSci Research, Accessing cancer treatments can often be influenced by a range of financial considerations. From the cost of medications and therapies to the expenses associated with hospital stays and follow-up care, the financial burden can be significant. Adequate financial resources not only help cover these costs but also play a critical role in providing comprehensive patient support services.

Moreover, finances are indispensable in supporting research and innovation in cancer therapy. Increased funding allows researchers to explore new avenues and develop novel approaches to cancer treatment. It empowers scientists to conduct clinical trials, invest in advanced technologies, and collaborate with other experts in the field. This ongoing research and innovation not only drive the development of new treatments but also enable the improvement of existing ones. By continuously refining and optimizing cancer therapies, patients can benefit from more effective and targeted interventions, ultimately leading to better outcomes and higher chances of remission.

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